BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

861 related articles for article (PubMed ID: 16489022)

  • 1. The tumor suppressor Smad4 is required for transforming growth factor beta-induced epithelial to mesenchymal transition and bone metastasis of breast cancer cells.
    Deckers M; van Dinther M; Buijs J; Que I; Löwik C; van der Pluijm G; ten Dijke P
    Cancer Res; 2006 Feb; 66(4):2202-9. PubMed ID: 16489022
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer.
    Buijs JT; Henriquez NV; van Overveld PG; van der Horst G; Que I; Schwaninger R; Rentsch C; Ten Dijke P; Cleton-Jansen AM; Driouch K; Lidereau R; Bachelier R; Vukicevic S; Clézardin P; Papapoulos SE; Cecchini MG; Löwik CW; van der Pluijm G
    Cancer Res; 2007 Sep; 67(18):8742-51. PubMed ID: 17875715
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Transcriptome profiling of a TGF-beta-induced epithelial-to-mesenchymal transition reveals extracellular clusterin as a target for therapeutic antibodies.
    Lenferink AE; Cantin C; Nantel A; Wang E; Durocher Y; Banville M; Paul-Roc B; Marcil A; Wilson MR; O'Connor-McCourt MD
    Oncogene; 2010 Feb; 29(6):831-44. PubMed ID: 19935703
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of RNAi-mediated Smad4 silencing on growth and apoptosis of human rhabdomyosarcoma cells.
    Ye L; Zhang H; Zhang L; Yang G; Ke Q; Guo H; Bu H
    Int J Oncol; 2006 Nov; 29(5):1149-57. PubMed ID: 17016646
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Smad4 dependency defines two classes of transforming growth factor {beta} (TGF-{beta}) target genes and distinguishes TGF-{beta}-induced epithelial-mesenchymal transition from its antiproliferative and migratory responses.
    Levy L; Hill CS
    Mol Cell Biol; 2005 Sep; 25(18):8108-25. PubMed ID: 16135802
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Silencing of transforming growth factor-beta1 in situ by RNA interference for breast cancer: implications for proliferation and migration in vitro and metastasis in vivo.
    Moore LD; Isayeva T; Siegal GP; Ponnazhagan S
    Clin Cancer Res; 2008 Aug; 14(15):4961-70. PubMed ID: 18676771
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Smad4 silencing in pancreatic cancer cell lines using stable RNA interference and gene expression profiles induced by transforming growth factor-beta.
    Jazag A; Ijichi H; Kanai F; Imamura T; Guleng B; Ohta M; Imamura J; Tanaka Y; Tateishi K; Ikenoue T; Kawakami T; Arakawa Y; Miyagishi M; Taira K; Kawabe T; Omata M
    Oncogene; 2005 Jan; 24(4):662-71. PubMed ID: 15592526
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Smad4-independent TGF-beta signaling in tumor cell migration.
    Giehl K; Imamichi Y; Menke A
    Cells Tissues Organs; 2007; 185(1-3):123-30. PubMed ID: 17587818
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Epithin, a target of transforming growth factor-beta signaling, mediates epithelial-mesenchymal transition.
    Lee HS; Kim C; Kim SB; Kim MG; Park D
    Biochem Biophys Res Commun; 2010 May; 395(4):553-9. PubMed ID: 20398629
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lentiviral-mediated Smad4 RNAi induced anti-proliferation by p16 up-regulation and apoptosis by caspase 3 down-regulation in hepatoma SMMC-7721 cells.
    Huang S; Zhang F; Miao L; Zhang H; Fan Z; Wang X; Ji G
    Oncol Rep; 2008 Nov; 20(5):1053-9. PubMed ID: 18949401
    [TBL] [Abstract][Full Text] [Related]  

  • 11. SMAD4 mediates mesenchymal-epithelial reversion in SW480 colon carcinoma cells.
    Pohl M; Radacz Y; Pawlik N; Schoeneck A; Baldus SE; Munding J; Schmiegel W; Schwarte-Waldhoff I; Reinacher-Schick A
    Anticancer Res; 2010 Jul; 30(7):2603-13. PubMed ID: 20682989
    [TBL] [Abstract][Full Text] [Related]  

  • 12. TGF beta-induced focal complex formation in epithelial cells is mediated by activated ERK and JNK MAP kinases and is independent of Smad4.
    Imamichi Y; Waidmann O; Hein R; Eleftheriou P; Giehl K; Menke A
    Biol Chem; 2005 Mar; 386(3):225-36. PubMed ID: 15843168
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Stimulation of cyclooxygenase-2 expression by bone-derived transforming growth factor-beta enhances bone metastases in breast cancer.
    Hiraga T; Myoui A; Choi ME; Yoshikawa H; Yoneda T
    Cancer Res; 2006 Feb; 66(4):2067-73. PubMed ID: 16489006
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sp1 is required for transforming growth factor-beta-induced mesenchymal transition and migration in pancreatic cancer cells.
    Jungert K; Buck A; von Wichert G; Adler G; König A; Buchholz M; Gress TM; Ellenrieder V
    Cancer Res; 2007 Feb; 67(4):1563-70. PubMed ID: 17308095
    [TBL] [Abstract][Full Text] [Related]  

  • 15. EW-7203, a novel small molecule inhibitor of transforming growth factor-β (TGF-β) type I receptor/activin receptor-like kinase-5, blocks TGF-β1-mediated epithelial-to-mesenchymal transition in mammary epithelial cells.
    Park CY; Kim DK; Sheen YY
    Cancer Sci; 2011 Oct; 102(10):1889-96. PubMed ID: 21707864
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A tumor-protective role for human kallikrein-related peptidase 6 in breast cancer mediated by inhibition of epithelial-to-mesenchymal transition.
    Pampalakis G; Prosnikli E; Agalioti T; Vlahou A; Zoumpourlis V; Sotiropoulou G
    Cancer Res; 2009 May; 69(9):3779-87. PubMed ID: 19383923
    [TBL] [Abstract][Full Text] [Related]  

  • 17. NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression.
    Huber MA; Azoitei N; Baumann B; Grünert S; Sommer A; Pehamberger H; Kraut N; Beug H; Wirth T
    J Clin Invest; 2004 Aug; 114(4):569-81. PubMed ID: 15314694
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Bone morphogenetic protein signaling enhances invasion and bone metastasis of breast cancer cells through Smad pathway.
    Katsuno Y; Hanyu A; Kanda H; Ishikawa Y; Akiyama F; Iwase T; Ogata E; Ehata S; Miyazono K; Imamura T
    Oncogene; 2008 Oct; 27(49):6322-33. PubMed ID: 18663362
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sustained TGF beta exposure suppresses Smad and non-Smad signalling in mammary epithelial cells, leading to EMT and inhibition of growth arrest and apoptosis.
    Gal A; Sjöblom T; Fedorova L; Imreh S; Beug H; Moustakas A
    Oncogene; 2008 Feb; 27(9):1218-30. PubMed ID: 17724470
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activation of extracellular signal-regulated kinase by TGF-beta1 via TbetaRII and Smad7 dependent mechanisms in human bronchial epithelial BEP2D cells.
    Huo YY; Hu YC; He XR; Wang Y; Song BQ; Zhou PK; Zhu MX; Li G; Wu DC
    Cell Biol Toxicol; 2007 Mar; 23(2):113-28. PubMed ID: 17096210
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 44.