These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

193 related articles for article (PubMed ID: 16492761)

  • 1. An efficient rapid system for profiling the cellular activities of molecular libraries.
    Melnick JS; Janes J; Kim S; Chang JY; Sipes DG; Gunderson D; Jarnes L; Matzen JT; Garcia ME; Hood TL; Beigi R; Xia G; Harig RA; Asatryan H; Yan SF; Zhou Y; Gu XJ; Saadat A; Zhou V; King FJ; Shaw CM; Su AI; Downs R; Gray NS; Schultz PG; Warmuth M; Caldwell JS
    Proc Natl Acad Sci U S A; 2006 Feb; 103(9):3153-8. PubMed ID: 16492761
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Small-molecule kinase-inhibitor target assessment.
    Kung C; Shokat KM
    Chembiochem; 2005 Mar; 6(3):523-6. PubMed ID: 15696508
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of compound 584, an Abl kinase inhibitor with lasting effects.
    Puttini M; Redaelli S; Moretti L; Brussolo S; Gunby RH; Mologni L; Marchesi E; Cleris L; Donella-Deana A; Drueckes P; Sala E; Lucchini V; Kubbutat M; Formelli F; Zambon A; Scapozza L; Gambacorti-Passerini C
    Haematologica; 2008 May; 93(5):653-61. PubMed ID: 18367480
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Imatinib mesylate (STI571)-induced cell edge translocation of kinase-active and kinase-defective Abelson kinase: requirements of myristoylation and src homology 3 domain.
    Fujita A; Shishido T; Yuan Y; Inamoto E; Narumiya S; Watanabe N
    Mol Pharmacol; 2009 Jan; 75(1):75-84. PubMed ID: 18835981
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Abl protein-tyrosine kinase inhibitor STI571 inhibits in vitro signal transduction mediated by c-kit and platelet-derived growth factor receptors.
    Buchdunger E; Cioffi CL; Law N; Stover D; Ohno-Jones S; Druker BJ; Lydon NB
    J Pharmacol Exp Ther; 2000 Oct; 295(1):139-45. PubMed ID: 10991971
    [TBL] [Abstract][Full Text] [Related]  

  • 6. High-throughput biochemical kinase selectivity assays: panel development and screening applications.
    Card A; Caldwell C; Min H; Lokchander B; Hualin Xi ; Sciabola S; Kamath AV; Clugston SL; Tschantz WR; Leyu Wang ; Moshinsky DJ
    J Biomol Screen; 2009 Jan; 14(1):31-42. PubMed ID: 19073965
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Development and applications of a broad-coverage, TR-FRET-based kinase binding assay platform.
    Lebakken CS; Riddle SM; Singh U; Frazee WJ; Eliason HC; Gao Y; Reichling LJ; Marks BD; Vogel KW
    J Biomol Screen; 2009 Sep; 14(8):924-35. PubMed ID: 19564447
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Kinase inhibitor data modeling and de novo inhibitor design with fragment approaches.
    Vieth M; Erickson J; Wang J; Webster Y; Mader M; Higgs R; Watson I
    J Med Chem; 2009 Oct; 52(20):6456-66. PubMed ID: 19791746
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Global target profile of the kinase inhibitor bosutinib in primary chronic myeloid leukemia cells.
    Remsing Rix LL; Rix U; Colinge J; Hantschel O; Bennett KL; Stranzl T; Müller A; Baumgartner C; Valent P; Augustin M; Till JH; Superti-Furga G
    Leukemia; 2009 Mar; 23(3):477-85. PubMed ID: 19039322
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Preclinical characterization of ABT-348, a kinase inhibitor targeting the aurora, vascular endothelial growth factor receptor/platelet-derived growth factor receptor, and Src kinase families.
    Glaser KB; Li J; Marcotte PA; Magoc TJ; Guo J; Reuter DR; Tapang P; Wei RQ; Pease LJ; Bui MH; Chen Z; Frey RR; Johnson EF; Osterling DJ; Olson AM; Bouska JJ; Luo Y; Curtin ML; Donawho CK; Michaelides MR; Tse C; Davidsen SK; Albert DH
    J Pharmacol Exp Ther; 2012 Dec; 343(3):617-27. PubMed ID: 22935731
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Profile-QSAR: a novel meta-QSAR method that combines activities across the kinase family to accurately predict affinity, selectivity, and cellular activity.
    Martin E; Mukherjee P; Sullivan D; Jansen J
    J Chem Inf Model; 2011 Aug; 51(8):1942-56. PubMed ID: 21667971
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Virtual screening of Abl inhibitors from large compound libraries by support vector machines.
    Liu XH; Ma XH; Tan CY; Jiang YY; Go ML; Low BC; Chen YZ
    J Chem Inf Model; 2009 Sep; 49(9):2101-10. PubMed ID: 19689138
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A high-throughput, nonisotopic, competitive binding assay for kinases using nonselective inhibitor probes (ED-NSIP).
    Vainshtein I; Silveria S; Kaul P; Rouhani R; Eglen RM; Wang J
    J Biomol Screen; 2002 Dec; 7(6):507-14. PubMed ID: 14599348
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expression and activity of SRC regulate interleukin-8 expression in pancreatic adenocarcinoma cells: implications for angiogenesis.
    Trevino JG; Summy JM; Gray MJ; Nilsson MB; Lesslie DP; Baker CH; Gallick GE
    Cancer Res; 2005 Aug; 65(16):7214-22. PubMed ID: 16103072
    [TBL] [Abstract][Full Text] [Related]  

  • 15. [Screening marine resources to find novel chemical inhibitors of disease-relevant protein kinases].
    Baratte B; Serive B; Bach S
    Med Sci (Paris); 2015 May; 31(5):538-45. PubMed ID: 26059305
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interaction profiles of protein kinase-inhibitor complexes and their application to virtual screening.
    Chuaqui C; Deng Z; Singh J
    J Med Chem; 2005 Jan; 48(1):121-33. PubMed ID: 15634006
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The selective tyrosine kinase inhibitor STI571 inhibits small cell lung cancer growth.
    Krystal GW; Honsawek S; Litz J; Buchdunger E
    Clin Cancer Res; 2000 Aug; 6(8):3319-26. PubMed ID: 10955819
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Potent inhibition of platelet-derived growth factor-induced responses in vascular smooth muscle cells by BMS-354825 (dasatinib).
    Chen Z; Lee FY; Bhalla KN; Wu J
    Mol Pharmacol; 2006 May; 69(5):1527-33. PubMed ID: 16436588
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Virtual screening of selective multitarget kinase inhibitors by combinatorial support vector machines.
    Ma XH; Wang R; Tan CY; Jiang YY; Lu T; Rao HB; Li XY; Go ML; Low BC; Chen YZ
    Mol Pharm; 2010 Oct; 7(5):1545-60. PubMed ID: 20712327
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Kinase-kernel models: accurate in silico screening of 4 million compounds across the entire human kinome.
    Martin E; Mukherjee P
    J Chem Inf Model; 2012 Jan; 52(1):156-70. PubMed ID: 22133092
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.