These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
210 related articles for article (PubMed ID: 16493467)
1. A divergent synthesis of 2-acyl derivatives of PUGNAc yields selective inhibitors of O-GlcNAcase. Stubbs KA; Zhang N; Vocadlo DJ Org Biomol Chem; 2006 Mar; 4(5):839-45. PubMed ID: 16493467 [TBL] [Abstract][Full Text] [Related]
2. Insight into a strategy for attenuating AmpC-mediated beta-lactam resistance: structural basis for selective inhibition of the glycoside hydrolase NagZ. Balcewich MD; Stubbs KA; He Y; James TW; Davies GJ; Vocadlo DJ; Mark BL Protein Sci; 2009 Jul; 18(7):1541-51. PubMed ID: 19499593 [TBL] [Abstract][Full Text] [Related]
3. Inhibition of O-GlcNAcase by a gluco-configured nagstatin and a PUGNAc-imidazole hybrid inhibitor. Shanmugasundaram B; Debowski AW; Dennis RJ; Davies GJ; Vocadlo DJ; Vasella A Chem Commun (Camb); 2006 Nov; (42):4372-4. PubMed ID: 17057847 [TBL] [Abstract][Full Text] [Related]
4. The synthesis and biological evaluation of some carbocyclic analogues of PUGNAc. Scaffidi A; Stubbs KA; Vocadlo DJ; Stick RV Carbohydr Res; 2008 Nov; 343(16):2744-53. PubMed ID: 18804755 [TBL] [Abstract][Full Text] [Related]
5. Identification of a specific inhibitor of nOGA - a caspase-3 cleaved O-GlcNAcase variant during apoptosis. Li J; Li Z; Li T; Lin L; Zhang Y; Guo L; Xu Y; Zhao W; Wang P Biochemistry (Mosc); 2012 Feb; 77(2):194-200. PubMed ID: 22348480 [TBL] [Abstract][Full Text] [Related]
6. Analysis of PUGNAc and NAG-thiazoline as transition state analogues for human O-GlcNAcase: mechanistic and structural insights into inhibitor selectivity and transition state poise. Whitworth GE; Macauley MS; Stubbs KA; Dennis RJ; Taylor EJ; Davies GJ; Greig IR; Vocadlo DJ J Am Chem Soc; 2007 Jan; 129(3):635-44. PubMed ID: 17227027 [TBL] [Abstract][Full Text] [Related]
7. Computational analysis of human OGA structure in complex with PUGNAc and NAG-thiazoline derivatives. de Alencar NA; Sousa PR; Silva JR; Lameira J; Alves CN; Martí S; Moliner V J Chem Inf Model; 2012 Oct; 52(10):2775-83. PubMed ID: 22937904 [TBL] [Abstract][Full Text] [Related]
8. An O-GlcNAcase-specific inhibitor and substrate engineered by the extension of the N-acetyl moiety. Kim EJ; Perreira M; Thomas CJ; Hanover JA J Am Chem Soc; 2006 Apr; 128(13):4234-5. PubMed ID: 16568991 [TBL] [Abstract][Full Text] [Related]
9. Streptozotocin-induced beta-cell death is independent of its inhibition of O-GlcNAcase in pancreatic Min6 cells. Gao Y; Parker GJ; Hart GW Arch Biochem Biophys; 2000 Nov; 383(2):296-302. PubMed ID: 11185566 [TBL] [Abstract][Full Text] [Related]
10. Relationship between protein O-linked glycosylation and insulin-stimulated glucose transport in rat skeletal muscle following calorie restriction or exposure to O-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino-N-phenylcarbamate. Arias EB; Cartee GD Acta Physiol Scand; 2005 Mar; 183(3):281-9. PubMed ID: 15743388 [TBL] [Abstract][Full Text] [Related]
11. A quantum mechanics/molecular mechanics study of the protein-ligand interaction of two potent inhibitors of human O-GlcNAcase: PUGNAc and NAG-thiazoline. Lameira J; Alves CN; Moliner V; Martí S; Kanaan N; Tuñón I J Phys Chem B; 2008 Nov; 112(45):14260-6. PubMed ID: 18939790 [TBL] [Abstract][Full Text] [Related]
12. Active-pocket size differentiating insectile from bacterial chitinolytic β-N-acetyl-D-hexosaminidases. Liu T; Zhang H; Liu F; Chen L; Shen X; Yang Q Biochem J; 2011 Sep; 438(3):467-74. PubMed ID: 21692744 [TBL] [Abstract][Full Text] [Related]
13. Inhibition of O-GlcNAcase by PUGNAc is dependent upon the oxime stereochemistry. Perreira M; Kim EJ; Thomas CJ; Hanover JA Bioorg Med Chem; 2006 Feb; 14(3):837-46. PubMed ID: 16214344 [TBL] [Abstract][Full Text] [Related]
14. Development of GlcNAc-inspired iminocyclitiols as potent and selective N-acetyl-beta-hexosaminidase inhibitors. Ho CW; Popat SD; Liu TW; Tsai KC; Ho MJ; Chen WH; Yang AS; Lin CH ACS Chem Biol; 2010 May; 5(5):489-97. PubMed ID: 20187655 [TBL] [Abstract][Full Text] [Related]
15. Proteomics and PUGNAcity will overcome questioning of insulin resistance induction by nonselective inhibition of O-GlcNAcase. Dehennaut V; Lefebvre T Proteomics; 2013 Oct; 13(20):2944-6. PubMed ID: 23983178 [TBL] [Abstract][Full Text] [Related]
16. Quantum mechanical/molecular mechanical molecular dynamics simulation of wild-type and seven mutants of CpNagJ in complex with PUGNAc. Lameira J; Alves CN; Moliner V; Martí S; Castillo R; Tuñón I J Phys Chem B; 2010 May; 114(20):7029-36. PubMed ID: 20429600 [TBL] [Abstract][Full Text] [Related]
17. Modulation of O-linked N-acetylglucosamine levels on nuclear and cytoplasmic proteins in vivo using the peptide O-GlcNAc-beta-N-acetylglucosaminidase inhibitor O-(2-acetamido-2-deoxy-D-glucopyranosylidene)amino-N-phenylcarbamate. Haltiwanger RS; Grove K; Philipsberg GA J Biol Chem; 1998 Feb; 273(6):3611-7. PubMed ID: 9452489 [TBL] [Abstract][Full Text] [Related]
18. Conformational flexibility of the glycosidase NagZ allows it to bind structurally diverse inhibitors to suppress β-lactam antibiotic resistance. Vadlamani G; Stubbs KA; Désiré J; Blériot Y; Vocadlo DJ; Mark BL Protein Sci; 2017 Jun; 26(6):1161-1170. PubMed ID: 28370529 [TBL] [Abstract][Full Text] [Related]
19. Enzymatic characterization and inhibition of the nuclear variant of human O-GlcNAcase. Macauley MS; Vocadlo DJ Carbohydr Res; 2009 Jun; 344(9):1079-84. PubMed ID: 19423084 [TBL] [Abstract][Full Text] [Related]
20. Modifying the phenyl group of PUGNAc: reactivity tuning to deliver selective inhibitors for N-acetyl-D-glucosaminidases. Hattie M; Cekic N; Debowski AW; Vocadlo DJ; Stubbs KA Org Biomol Chem; 2016 Mar; 14(12):3193-7. PubMed ID: 26924385 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]