148 related articles for article (PubMed ID: 1649498)
1. Imidazoquinoline derivatives: potent inhibitors of platelet cAMP phosphodiesterase which elevate cAMP levels and activate protein kinase in platelets.
Seiler S; Gillespie E; Arnold AJ; Brassard CL; Meanwell NA; Fleming JS
Thromb Res; 1991 Apr; 62(1-2):31-42. PubMed ID: 1649498
[TBL] [Abstract][Full Text] [Related]
2. Inhibitors of blood platelet cAMP phosphodiesterase. 2. Structure-activity relationships associated with 1,3-dihydro-2H-imidazo[4,5-b]quinolin-2-ones substituted with functionalized side chains.
Meanwell NA; Pearce BC; Roth HR; Smith EC; Wedding DL; Wright JJ; Buchanan JO; Baryla UM; Gamberdella M; Gillespie E
J Med Chem; 1992 Jul; 35(14):2672-87. PubMed ID: 1321910
[TBL] [Abstract][Full Text] [Related]
3. Activation of cyclic GMP-binding and cyclic AMP-specific phosphodiesterases of rat platelets by a mechanism involving cyclic AMP-dependent phosphorylation.
Tremblay J; Lachance B; Hamet P
J Cyclic Nucleotide Protein Phosphor Res; 1985; 10(4):397-411. PubMed ID: 2411769
[TBL] [Abstract][Full Text] [Related]
4. Y-590 (a new pyridazinone derivative), a potent anti-thrombotic agent--II. Inhibition of platelet phosphodiesterase.
Mikashima H; Nakao T; Goto K; Ochi H; Yasuda H; Tsumagari T
Thromb Res; 1984 Sep; 35(5):589-94. PubMed ID: 6091293
[TBL] [Abstract][Full Text] [Related]
5. Intact cell and cell-free phosphorylation and concomitant activation of a low Km, cAMP phosphodiesterase found in human platelets.
Macphee CH; Reifsnyder DH; Moore TA; Beavo JA
J Cyclic Nucleotide Protein Phosphor Res; 1986-1987; 11(7):487-96. PubMed ID: 2831258
[TBL] [Abstract][Full Text] [Related]
6. Inhibition of human platelet cyclic AMP phosphodiesterase and of platelet aggregation by a hemisynthetic flavonoid, amentoflavone hexaacetate.
Beretz A; Briançon-Scheid F; Stierlé A; Corre G; Anton R; Cazenave JP
Biochem Pharmacol; 1986 Jan; 35(2):257-62. PubMed ID: 3002388
[TBL] [Abstract][Full Text] [Related]
7. Selective inhibitor of platelet cyclic adenosine monophosphate phosphodiesterase, cilostamide, inhibits platelet aggregation.
Hidaka H; Hayashi H; Kohri H; Kimura Y; Hosokawa T; Igawa T; Saitoh Y
J Pharmacol Exp Ther; 1979 Oct; 211(1):26-30. PubMed ID: 226672
[No Abstract] [Full Text] [Related]
8. Antithrombotic activity of BMY-43351, a new imidazoquinoline with enhanced aqueous solubility.
Fleming JS; Buchanan JO; Seiler SM; Meanwell NA
Thromb Res; 1991 Jul; 63(1):145-55. PubMed ID: 1948816
[TBL] [Abstract][Full Text] [Related]
9. 7-Bromo-1,5-dihydro-3,6-dimethylimidazo[2,1-b]quinazolin-2(3H)- one (Ro 15-2041), a potent antithrombotic agent that selectively inhibits platelet cyclic AMP-phosphodiesterase.
Muggli R; Tschopp TB; Mittelholzer E; Baumgartner HR
J Pharmacol Exp Ther; 1985 Oct; 235(1):212-9. PubMed ID: 2995647
[TBL] [Abstract][Full Text] [Related]
10. Inhibition of platelet aggregation by the cAMP-phosphodiesterase inhibitor, cilostamide, may not be associated with activation of cAMP-dependent protein kinase.
Nishikawa M; Komada F; Morita K; Deguchi K; Shirakawa S
Cell Signal; 1992 Jul; 4(4):453-63. PubMed ID: 1329900
[TBL] [Abstract][Full Text] [Related]
11. 2-Aminochromones block human platelet aggregation by inhibiting cyclic AMP-dependent phosphodiesterase leading to reduced platelet phospholipase C activity.
Benjamin CW; Lin AH; Morris J; Wishka DG; Gorman RR
J Pharmacol Exp Ther; 1993 Apr; 265(1):457-62. PubMed ID: 7682615
[TBL] [Abstract][Full Text] [Related]
12. Effect of cAMP phosphodiesterase inhibitors on ADP-induced shape change, cAMP and nucleoside diphosphokinase activity of rabbit platelets.
Lam SC; Guccione MA; Packham MA; Mustard JF
Thromb Haemost; 1982 Apr; 47(2):90-5. PubMed ID: 6285543
[TBL] [Abstract][Full Text] [Related]
13. 1,3-Dihydro-2H-imidazo[4,5-b]quinolin-2-ones--inhibitors of blood platelet cAMP phosphodiesterase and induced aggregation.
Meanwell NA; Roth HR; Smith EC; Wedding DL; Wright JJ; Fleming JS; Gillespie E
J Med Chem; 1991 Sep; 34(9):2906-16. PubMed ID: 1654430
[TBL] [Abstract][Full Text] [Related]
14. Phosphorylation results in activation of a cAMP phosphodiesterase in human platelets.
Macphee CH; Reifsnyder DH; Moore TA; Lerea KM; Beavo JA
J Biol Chem; 1988 Jul; 263(21):10353-8. PubMed ID: 2839485
[TBL] [Abstract][Full Text] [Related]
15. Inhibitors of blood platelet cAMP phosphodiesterase. 3. 1,3-Dihydro-2H-imidazo[4,5-b]quinolin-2-one derivatives with enhanced aqueous solubility.
Meanwell NA; Dennis RD; Roth HR; Rosenfeld MJ; Smith EC; Wright JJ; Buchanan JO; Brassard CL; Gamberdella M; Gillespie E
J Med Chem; 1992 Jul; 35(14):2688-96. PubMed ID: 1321911
[TBL] [Abstract][Full Text] [Related]
16. Subcellular distribution of high-affinity type IV cyclic AMP phosphodiesterase activity in rabbit ventricular myocardium: relations to the effects of cardiotonic drugs.
Kithas PA; Artman M; Thompson WJ; Strada SJ
Circ Res; 1988 Apr; 62(4):782-9. PubMed ID: 2832097
[TBL] [Abstract][Full Text] [Related]
17. Pharmacology of a potent, new antithrombotic agent, 1,3-dihydro-7,8-dimethyl-2H-imidazo[4,5-b]quinolin-2-one (BMY-20844).
Buchanan JO; Fleming JS; Cornish BT; Baryla UM; Gillespie E; Stanton HC; Seiler SM; Keely SL
Thromb Res; 1989 Nov; 56(3):333-46. PubMed ID: 2559492
[TBL] [Abstract][Full Text] [Related]
18. Subcellular distribution of high-affinity type IV cyclic AMP phosphodiesterase activities in rabbit ventricular myocardium: relations to post-natal maturation.
Kithas PA; Artman M; Thompson WJ; Strada SJ
J Mol Cell Cardiol; 1989 May; 21(5):507-17. PubMed ID: 2550653
[TBL] [Abstract][Full Text] [Related]
19. Octimibate, a potent non-prostanoid inhibitor of platelet aggregation, acts via the prostacyclin receptor.
Merritt JE; Hallam TJ; Brown AM; Boyfield I; Cooper DG; Hickey DM; Jaxa-Chamiec AA; Kaumann AJ; Keen M; Kelly E
Br J Pharmacol; 1991 Jan; 102(1):251-9. PubMed ID: 1710526
[TBL] [Abstract][Full Text] [Related]
20. Inhibition of human cardiac cyclic AMP-phosphodiesterases by R 80122, a new selective cyclic AMP-phosphodiesterase III inhibitor: a comparison with other cardiotonic compounds.
de Cheffoy de Courcelles D; de Loore K; Freyne E; Janssen PA
J Pharmacol Exp Ther; 1992 Oct; 263(1):6-14. PubMed ID: 1328613
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]