356 related articles for article (PubMed ID: 16500715)
1. Constitutive receptor activity series: endogenous inverse agonists and constitutive receptor activity in the melanocortin system.
Adan RA
Trends Pharmacol Sci; 2006 Apr; 27(4):183-6. PubMed ID: 16500715
[TBL] [Abstract][Full Text] [Related]
2. Constitutive activity of neural melanocortin receptors.
Tao YX; Huang H; Wang ZQ; Yang F; Williams JN; Nikiforovich GV
Methods Enzymol; 2010; 484():267-79. PubMed ID: 21036237
[TBL] [Abstract][Full Text] [Related]
3. Overview of endogenous and synthetic melanocortin peptides.
Wilson KR; Todorovic A; Proneth B; Haskell-Luevano C
Cell Mol Biol (Noisy-le-grand); 2006 May; 52(2):3-20. PubMed ID: 16914082
[TBL] [Abstract][Full Text] [Related]
4. Pharmacological characterization of 40 human melanocortin-4 receptor polymorphisms with the endogenous proopiomelanocortin-derived agonists and the agouti-related protein (AGRP) antagonist.
Xiang Z; Litherland SA; Sorensen NB; Proneth B; Wood MS; Shaw AM; Millard WJ; Haskell-Luevano C
Biochemistry; 2006 Jun; 45(23):7277-88. PubMed ID: 16752916
[TBL] [Abstract][Full Text] [Related]
5. Identification of putative agouti-related protein(87-132)-melanocortin-4 receptor interactions by homology molecular modeling and validation using chimeric peptide ligands.
Wilczynski A; Wang XS; Joseph CG; Xiang Z; Bauzo RM; Scott JW; Sorensen NB; Shaw AM; Millard WJ; Richards NG; Haskell-Luevano C
J Med Chem; 2004 Apr; 47(9):2194-207. PubMed ID: 15084118
[TBL] [Abstract][Full Text] [Related]
6. Molecular mechanism of the constitutive activation of the L250Q human melanocortin-4 receptor polymorphism.
Proneth B; Xiang Z; Pogozheva ID; Litherland SA; Gorbatyuk OS; Shaw AM; Millard WJ; Mosberg HI; Haskell-Luevano C
Chem Biol Drug Des; 2006 Mar; 67(3):215-29. PubMed ID: 16611215
[TBL] [Abstract][Full Text] [Related]
7. New ligands for melanocortin receptors.
Kaelin CB; Candille SI; Yu B; Jackson P; Thompson DA; Nix MA; Binkley J; Millhauser GL; Barsh GS
Int J Obes (Lond); 2008 Dec; 32 Suppl 7():S19-27. PubMed ID: 19136986
[TBL] [Abstract][Full Text] [Related]
8. Stereochemical studies of the monocyclic agouti-related protein (103-122) Arg-Phe-Phe residues: conversion of a melanocortin-4 receptor antagonist into an agonist and results in the discovery of a potent and selective melanocortin-1 agonist.
Joseph CG; Wang XS; Scott JW; Bauzo RM; Xiang Z; Richards NG; Haskell-Luevano C
J Med Chem; 2004 Dec; 47(27):6702-10. PubMed ID: 15615519
[TBL] [Abstract][Full Text] [Related]
9. N-terminal fatty acylated His-dPhe-Arg-Trp-NH(2) tetrapeptides: influence of fatty acid chain length on potency and selectivity at the mouse melanocortin receptors and human melanocytes.
Todorovic A; Holder JR; Bauzo RM; Scott JW; Kavanagh R; Abdel-Malek Z; Haskell-Luevano C
J Med Chem; 2005 May; 48(9):3328-36. PubMed ID: 15857138
[TBL] [Abstract][Full Text] [Related]
10. Inverse agonism gains weight.
Adan RA; Kas MJ
Trends Pharmacol Sci; 2003 Jun; 24(6):315-21. PubMed ID: 12823958
[TBL] [Abstract][Full Text] [Related]
11. Molecular basis of melanocortin-4 receptor for AGRP inverse agonism.
Chen M; Celik A; Georgeson KE; Harmon CM; Yang Y
Regul Pept; 2006 Sep; 136(1-3):40-9. PubMed ID: 16820227
[TBL] [Abstract][Full Text] [Related]
12. Receptor-antagonist interactions in the complexes of agouti and agouti-related protein with human melanocortin 1 and 4 receptors.
Chai BX; Pogozheva ID; Lai YM; Li JY; Neubig RR; Mosberg HI; Gantz I
Biochemistry; 2005 Mar; 44(9):3418-31. PubMed ID: 15736952
[TBL] [Abstract][Full Text] [Related]
13. Constitutive activity of the melanocortin-4 receptor is maintained by its N-terminal domain and plays a role in energy homeostasis in humans.
Srinivasan S; Lubrano-Berthelier C; Govaerts C; Picard F; Santiago P; Conklin BR; Vaisse C
J Clin Invest; 2004 Oct; 114(8):1158-64. PubMed ID: 15489963
[TBL] [Abstract][Full Text] [Related]
14. Role of third intracellular loop of the melanocortin 4 receptor in the regulation of constitutive activity.
Kim DH; Shin SW; Baik JH
Biochem Biophys Res Commun; 2008 Jan; 365(3):439-45. PubMed ID: 17986382
[TBL] [Abstract][Full Text] [Related]
15. Neural melanocortin receptors are differentially expressed and regulated by stress in rat hypothalamic-pituitary-adrenal axis.
Wachira SJ; Hughes-Darden CA; Nicholas HB; Taylor CV; Robinson TJ
Cell Mol Biol (Noisy-le-grand); 2004 Sep; 50(6):703-13. PubMed ID: 15641161
[TBL] [Abstract][Full Text] [Related]
16. Novel pharmacological MC4R agonists can efficiently activate mutated MC4R from obese patient with impaired endogenous agonist response.
Roubert P; Dubern B; Plas P; Lubrano-Berthelier C; Alihi R; Auger F; Deoliveira DB; Dong JZ; Basdevant A; Thurieau C; Clément K
J Endocrinol; 2010 Nov; 207(2):177-83. PubMed ID: 20696697
[TBL] [Abstract][Full Text] [Related]
17. Aza-scanning of the potent melanocortin receptor agonist Ac-His-D-Phe-Arg-Trp-NH.
Boeglin D; Xiang Z; Sorenson NB; Wood MS; Haskell-Luevano C; Lubell WD
Chem Biol Drug Des; 2006 Apr; 67(4):275-83. PubMed ID: 16629825
[TBL] [Abstract][Full Text] [Related]
18. Constitutive activity in melanocortin-4 receptor: biased signaling of inverse agonists.
Tao YX
Adv Pharmacol; 2014; 70():135-54. PubMed ID: 24931195
[TBL] [Abstract][Full Text] [Related]
19. Regulation of melanocortin 1 receptor expression at the mRNA and protein levels by its natural agonist and antagonist.
Rouzaud F; Annereau JP; Valencia JC; Costin GE; Hearing VJ
FASEB J; 2003 Nov; 17(14):2154-6. PubMed ID: 14500544
[TBL] [Abstract][Full Text] [Related]
20. Peptide and small molecules rescue the functional activity and agonist potency of dysfunctional human melanocortin-4 receptor polymorphisms.
Xiang Z; Pogozheva ID; Sorenson NB; Wilczynski AM; Holder JR; Litherland SA; Millard WJ; Mosberg HI; Haskell-Luevano C
Biochemistry; 2007 Jul; 46(28):8273-87. PubMed ID: 17590021
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]