343 related articles for article (PubMed ID: 16505056)
1. RPE65 gene delivery restores isomerohydrolase activity and prevents early cone loss in Rpe65-/- mice.
Chen Y; Moiseyev G; Takahashi Y; Ma JX
Invest Ophthalmol Vis Sci; 2006 Mar; 47(3):1177-84. PubMed ID: 16505056
[TBL] [Abstract][Full Text] [Related]
2. Downregulation of cone-specific gene expression and degeneration of cone photoreceptors in the Rpe65-/- mouse at early ages.
Znoiko SL; Rohrer B; Lu K; Lohr HR; Crouch RK; Ma JX
Invest Ophthalmol Vis Sci; 2005 Apr; 46(4):1473-9. PubMed ID: 15790918
[TBL] [Abstract][Full Text] [Related]
3. Comparison of ocular pathologies in vitamin A-deficient mice and RPE65 gene knockout mice.
Hu Y; Chen Y; Moiseyev G; Takahashi Y; Mott R; Ma JX
Invest Ophthalmol Vis Sci; 2011 Jul; 52(8):5507-14. PubMed ID: 21551411
[TBL] [Abstract][Full Text] [Related]
4. Nrl-knockout mice deficient in Rpe65 fail to synthesize 11-cis retinal and cone outer segments.
Feathers KL; Lyubarsky AL; Khan NW; Teofilo K; Swaroop A; Williams DS; Pugh EN; Thompson DA
Invest Ophthalmol Vis Sci; 2008 Mar; 49(3):1126-35. PubMed ID: 18326740
[TBL] [Abstract][Full Text] [Related]
5. Lentiviral gene transfer of RPE65 rescues survival and function of cones in a mouse model of Leber congenital amaurosis.
Bemelmans AP; Kostic C; Crippa SV; Hauswirth WW; Lem J; Munier FL; Seeliger MW; Wenzel A; Arsenijevic Y
PLoS Med; 2006 Oct; 3(10):e347. PubMed ID: 17032058
[TBL] [Abstract][Full Text] [Related]
6. Loss of cone photoreceptors caused by chromophore depletion is partially prevented by the artificial chromophore pro-drug, 9-cis-retinyl acetate.
Maeda T; Cideciyan AV; Maeda A; Golczak M; Aleman TS; Jacobson SG; Palczewski K
Hum Mol Genet; 2009 Jun; 18(12):2277-87. PubMed ID: 19339306
[TBL] [Abstract][Full Text] [Related]
7. Protection of cone photoreceptor M-opsin degradation with 9-cis-β-carotene-rich alga Dunaliella bardawil in Rpe65(-/-) mouse retinal explant culture.
Ozaki T; Nakazawa M; Kudo T; Hirano S; Suzuki K; Ishiguro S
Curr Eye Res; 2014 Dec; 39(12):1221-31. PubMed ID: 25006880
[TBL] [Abstract][Full Text] [Related]
8. Cone opsin mislocalization in Rpe65-/- mice: a defect that can be corrected by 11-cis retinal.
Rohrer B; Lohr HR; Humphries P; Redmond TM; Seeliger MW; Crouch RK
Invest Ophthalmol Vis Sci; 2005 Oct; 46(10):3876-82. PubMed ID: 16186377
[TBL] [Abstract][Full Text] [Related]
9. RPE65 is essential for the function of cone photoreceptors in NRL-deficient mice.
Wenzel A; von Lintig J; Oberhauser V; Tanimoto N; Grimm C; Seeliger MW
Invest Ophthalmol Vis Sci; 2007 Feb; 48(2):534-42. PubMed ID: 17251447
[TBL] [Abstract][Full Text] [Related]
10. Cone outer segment morphology and cone function in the Rpe65-/- Nrl-/- mouse retina are amenable to retinoid replacement.
Kunchithapautham K; Coughlin B; Crouch RK; Rohrer B
Invest Ophthalmol Vis Sci; 2009 Oct; 50(10):4858-64. PubMed ID: 19407011
[TBL] [Abstract][Full Text] [Related]
11. RPE65 from cone-dominant chicken is a more efficient isomerohydrolase compared with that from rod-dominant species.
Moiseyev G; Takahashi Y; Chen Y; Kim S; Ma JX
J Biol Chem; 2008 Mar; 283(13):8110-7. PubMed ID: 18216020
[TBL] [Abstract][Full Text] [Related]
12. Effective and sustained delivery of hydrophobic retinoids to photoreceptors.
Tang PH; Fan J; Goletz PW; Wheless L; Crouch RK
Invest Ophthalmol Vis Sci; 2010 Nov; 51(11):5958-64. PubMed ID: 20574023
[TBL] [Abstract][Full Text] [Related]
13. Long-term restoration of rod and cone vision by single dose rAAV-mediated gene transfer to the retina in a canine model of childhood blindness.
Acland GM; Aguirre GD; Bennett J; Aleman TS; Cideciyan AV; Bennicelli J; Dejneka NS; Pearce-Kelling SE; Maguire AM; Palczewski K; Hauswirth WW; Jacobson SG
Mol Ther; 2005 Dec; 12(6):1072-82. PubMed ID: 16226919
[TBL] [Abstract][Full Text] [Related]
14. Two point mutations of RPE65 from patients with retinal dystrophies decrease the stability of RPE65 protein and abolish its isomerohydrolase activity.
Takahashi Y; Chen Y; Moiseyev G; Ma JX
J Biol Chem; 2006 Aug; 281(31):21820-21826. PubMed ID: 16754667
[TBL] [Abstract][Full Text] [Related]
15. Light prevents exogenous 11-cis retinal from maintaining cone photoreceptors in chromophore-deficient mice.
Fan J; Crouch RK; Kono M
Invest Ophthalmol Vis Sci; 2011 Apr; 52(5):2412-6. PubMed ID: 21228385
[TBL] [Abstract][Full Text] [Related]
16. Fatty acid transport protein 4 (FATP4) prevents light-induced degeneration of cone and rod photoreceptors by inhibiting RPE65 isomerase.
Li S; Lee J; Zhou Y; Gordon WC; Hill JM; Bazan NG; Miner JH; Jin M
J Neurosci; 2013 Feb; 33(7):3178-89. PubMed ID: 23407971
[TBL] [Abstract][Full Text] [Related]
17. Trafficking of membrane-associated proteins to cone photoreceptor outer segments requires the chromophore 11-cis-retinal.
Zhang H; Fan J; Li S; Karan S; Rohrer B; Palczewski K; Frederick JM; Crouch RK; Baehr W
J Neurosci; 2008 Apr; 28(15):4008-14. PubMed ID: 18400900
[TBL] [Abstract][Full Text] [Related]
18. Gene therapy rescues cone structure and function in the 3-month-old rd12 mouse: a model for midcourse RPE65 leber congenital amaurosis.
Li X; Li W; Dai X; Kong F; Zheng Q; Zhou X; Lü F; Chang B; Rohrer B; Hauswirth WW; Qu J; Pang JJ
Invest Ophthalmol Vis Sci; 2011 Jan; 52(1):7-15. PubMed ID: 21169527
[TBL] [Abstract][Full Text] [Related]
19. Mole quantity of RPE65 and its productivity in the generation of 11-cis-retinal from retinyl esters in the living mouse eye.
Lyubarsky AL; Savchenko AB; Morocco SB; Daniele LL; Redmond TM; Pugh EN
Biochemistry; 2005 Jul; 44(29):9880-8. PubMed ID: 16026160
[TBL] [Abstract][Full Text] [Related]
20. Acute radiolabeling of retinoids in eye tissues of normal and rpe65-deficient mice.
Qtaishat NM; Redmond TM; Pepperberg DR
Invest Ophthalmol Vis Sci; 2003 Apr; 44(4):1435-46. PubMed ID: 12657577
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
