163 related articles for article (PubMed ID: 16507509)
1. Role of P-glycoprotein in the hepatic metabolism of tacrolimus.
Jeong H; Chiou WL
Xenobiotica; 2006 Jan; 36(1):1-13. PubMed ID: 16507509
[TBL] [Abstract][Full Text] [Related]
2. Disposition of tacrolimus in isolated perfused rat liver: influence of troleandomycin, cyclosporine, and gg918.
Wu CY; Benet LZ
Drug Metab Dispos; 2003 Nov; 31(11):1292-5. PubMed ID: 14570757
[TBL] [Abstract][Full Text] [Related]
3. In vitro and in vivo correlation of hepatic transporter effects on erythromycin metabolism: characterizing the importance of transporter-enzyme interplay.
Lam JL; Okochi H; Huang Y; Benet LZ
Drug Metab Dispos; 2006 Aug; 34(8):1336-44. PubMed ID: 16698890
[TBL] [Abstract][Full Text] [Related]
4. Impact of MDR1 and CYP3A5 on the oral clearance of tacrolimus and tacrolimus-related renal dysfunction in adult living-donor liver transplant patients.
Fukudo M; Yano I; Yoshimura A; Masuda S; Uesugi M; Hosohata K; Katsura T; Ogura Y; Oike F; Takada Y; Uemoto S; Inui K
Pharmacogenet Genomics; 2008 May; 18(5):413-23. PubMed ID: 18408564
[TBL] [Abstract][Full Text] [Related]
5. Elevated blood concentrations of calcineurin inhibitors during diarrheal episode in pediatric liver transplant recipients: involvement of the suppression of intestinal cytochrome P450 3A and P-glycoprotein.
Maezono S; Sugimoto K; Sakamoto K; Ohmori M; Hishikawa S; Mizuta K; Kawarasaki H; Watanabe Y; Fujimura A
Pediatr Transplant; 2005 Jun; 9(3):315-23. PubMed ID: 15910387
[TBL] [Abstract][Full Text] [Related]
6. Effects of a potent and specific P-glycoprotein inhibitor on the blood-brain barrier distribution and antinociceptive effect of morphine in the rat.
Letrent SP; Pollack GM; Brouwer KR; Brouwer KL
Drug Metab Dispos; 1999 Jul; 27(7):827-34. PubMed ID: 10383928
[TBL] [Abstract][Full Text] [Related]
7. Preclinical pharmacokinetic properties of the P-glycoprotein inhibitor GF120918A (HCl salt of GF120918, 9,10-dihydro-5-methoxy-9-oxo-N-[4-[2-(1,2,3,4-tetrahydro-6,7-dimethoxy-2-isoquinolinyl)ethyl]phenyl]-4-acridine-carboxamide) in the mouse, rat, dog, and monkey.
Ward KW; Azzarano LM
J Pharmacol Exp Ther; 2004 Aug; 310(2):703-9. PubMed ID: 15056727
[TBL] [Abstract][Full Text] [Related]
8. Effect of multidrug resistance modulators on the hepatobiliary disposition of doxorubicin in the isolated perfused rat liver.
Booth CL; Brouwer KR; Brouwer KL
Cancer Res; 1998 Aug; 58(16):3641-8. PubMed ID: 9721873
[TBL] [Abstract][Full Text] [Related]
9. Effect of hematocrit and albumin concentration on hepatic clearance of tacrolimus (FK506) during rabbit liver perfusion.
Chow FS; Piekoszewski W; Jusko WJ
Drug Metab Dispos; 1997 May; 25(5):610-6. PubMed ID: 9152601
[TBL] [Abstract][Full Text] [Related]
10. Evaluation of the modulation of P-glycoprotein (P-gp) on the intraocular disposition of its substrate in rabbits.
Senthilkumari S; Velpandian T; Biswas NR; Saxena R; Ghose S
Curr Eye Res; 2008 Apr; 33(4):333-43. PubMed ID: 18398708
[TBL] [Abstract][Full Text] [Related]
11. Mechanistic understanding of the different effects of Wuzhi Tablet (Schisandra sphenanthera extract) on the absorption and first-pass intestinal and hepatic metabolism of Tacrolimus (FK506).
Qin XL; Bi HC; Wang XD; Li JL; Wang Y; Xue XP; Chen X; Wang CX; Xu le J; Wang YT; Huang M
Int J Pharm; 2010 Apr; 389(1-2):114-21. PubMed ID: 20097278
[TBL] [Abstract][Full Text] [Related]
12. Limited interaction between tacrolimus and P-glycoprotein in the rat small intestine.
Saitoh H; Saikachi Y; Kobayashi M; Yamaguchi M; Oda M; Yuhki Y; Achiwa K; Tadano K; Takahashi Y; Aungst BJ
Eur J Pharm Sci; 2006 May; 28(1-2):34-42. PubMed ID: 16457995
[TBL] [Abstract][Full Text] [Related]
13. P-glycoprotein-mediated in vitro biliary excretion in sandwich-cultured rat hepatocytes.
Annaert PP; Turncliff RZ; Booth CL; Thakker DR; Brouwer KL
Drug Metab Dispos; 2001 Oct; 29(10):1277-83. PubMed ID: 11560870
[TBL] [Abstract][Full Text] [Related]
14. Hepatic microsome studies are insufficient to characterize in vivo hepatic metabolic clearance and metabolic drug-drug interactions: studies of digoxin metabolism in primary rat hepatocytes versus microsomes.
Lam JL; Benet LZ
Drug Metab Dispos; 2004 Nov; 32(11):1311-6. PubMed ID: 15483198
[TBL] [Abstract][Full Text] [Related]
15. Impact of curcumin-induced changes in P-glycoprotein and CYP3A expression on the pharmacokinetics of peroral celiprolol and midazolam in rats.
Zhang W; Tan TM; Lim LY
Drug Metab Dispos; 2007 Jan; 35(1):110-5. PubMed ID: 17050652
[TBL] [Abstract][Full Text] [Related]
16. The site-specific transport and metabolism of tacrolimus in rat small intestine.
Tamura S; Tokunaga Y; Ibuki R; Amidon GL; Sezaki H; Yamashita S
J Pharmacol Exp Ther; 2003 Jul; 306(1):310-6. PubMed ID: 12676880
[TBL] [Abstract][Full Text] [Related]
17. Alteration of fexofenadine disposition in the rat isolated perfused liver following injection of bacterial lipopolysaccharide.
Tong Y; Zhang R; Ngo SN; Davey AK
Clin Exp Pharmacol Physiol; 2006 Aug; 33(8):685-9. PubMed ID: 16895540
[TBL] [Abstract][Full Text] [Related]
18. Cerebral uptake of mefloquine enantiomers with and without the P-gp inhibitor elacridar (GF1210918) in mice.
Barraud de Lagerie S; Comets E; Gautrand C; Fernandez C; Auchere D; Singlas E; Mentre F; Gimenez F
Br J Pharmacol; 2004 Apr; 141(7):1214-22. PubMed ID: 15023856
[TBL] [Abstract][Full Text] [Related]
19. Novel double coated nanocapsules for intestinal delivery and enhanced oral bioavailability of tacrolimus, a P-gp substrate drug.
Nassar T; Rom A; Nyska A; Benita S
J Control Release; 2009 Jan; 133(1):77-84. PubMed ID: 18822327
[TBL] [Abstract][Full Text] [Related]
20. Effect of telaprevir on the metabolism and hepatic uptake of tacrolimus (FK506).
Oda K; Yamano K
Biopharm Drug Dispos; 2014 Dec; 35(9):501-12. PubMed ID: 25059890
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
