These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

424 related articles for article (PubMed ID: 16507982)

  • 1. Histone deacetylase inhibitors induce VHL and ubiquitin-independent proteasomal degradation of hypoxia-inducible factor 1alpha.
    Kong X; Lin Z; Liang D; Fath D; Sang N; Caro J
    Mol Cell Biol; 2006 Mar; 26(6):2019-28. PubMed ID: 16507982
    [TBL] [Abstract][Full Text] [Related]  

  • 2. JNK1 mediates degradation HIF-1alpha by a VHL-independent mechanism that involves the chaperones Hsp90/Hsp70.
    Zhang D; Li J; Costa M; Gao J; Huang C
    Cancer Res; 2010 Jan; 70(2):813-23. PubMed ID: 20068160
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1alpha from pVHL-independent degradation.
    Zhou J; Schmid T; Frank R; Brüne B
    J Biol Chem; 2004 Apr; 279(14):13506-13. PubMed ID: 14726529
    [TBL] [Abstract][Full Text] [Related]  

  • 4. AK-1, a SIRT2 inhibitor, destabilizes HIF-1α and diminishes its transcriptional activity during hypoxia.
    Lee SD; Kim W; Jeong JW; Park JW; Kim JE
    Cancer Lett; 2016 Apr; 373(1):138-145. PubMed ID: 26808575
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Histone deacetylase inhibitor induced pVHL-independent degradation of HIF-1α and hierarchical quality control of pVHL via chaperone system.
    Ni J; Ni A
    PLoS One; 2021; 16(7):e0248019. PubMed ID: 34329303
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Calcineurin promotes hypoxia-inducible factor 1alpha expression by dephosphorylating RACK1 and blocking RACK1 dimerization.
    Liu YV; Hubbi ME; Pan F; McDonald KR; Mansharamani M; Cole RN; Liu JO; Semenza GL
    J Biol Chem; 2007 Dec; 282(51):37064-73. PubMed ID: 17965024
    [TBL] [Abstract][Full Text] [Related]  

  • 7. p300 relieves p53-evoked transcriptional repression of hypoxia-inducible factor-1 (HIF-1).
    Schmid T; Zhou J; Köhl R; Brüne B
    Biochem J; 2004 May; 380(Pt 1):289-95. PubMed ID: 14992692
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Regulation of the HIF-1alpha stability by histone deacetylases.
    Kim SH; Jeong JW; Park JA; Lee JW; Seo JH; Jung BK; Bae MK; Kim KW
    Oncol Rep; 2007 Mar; 17(3):647-51. PubMed ID: 17273746
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phosphorylation of the von Hippel-Lindau protein (VHL) by protein kinase CK2 reduces its protein stability and affects p53 and HIF-1alpha mediated transcription.
    Ampofo E; Kietzmann T; Zimmer A; Jakupovic M; Montenarh M; Götz C
    Int J Biochem Cell Biol; 2010 Oct; 42(10):1729-35. PubMed ID: 20637892
    [TBL] [Abstract][Full Text] [Related]  

  • 10. COMMD1 Promotes pVHL and O2-Independent Proteolysis of HIF-1alpha via HSP90/70.
    van de Sluis B; Groot AJ; Vermeulen J; van der Wall E; van Diest PJ; Wijmenga C; Klomp LW; Vooijs M
    PLoS One; 2009 Oct; 4(10):e7332. PubMed ID: 19802386
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Flavonoids-induced accumulation of hypoxia-inducible factor (HIF)-1alpha/2alpha is mediated through chelation of iron.
    Park SS; Bae I; Lee YJ
    J Cell Biochem; 2008 Apr; 103(6):1989-98. PubMed ID: 17973296
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The histone deacetylase inhibitor, Vorinostat, represses hypoxia inducible factor 1 alpha expression through translational inhibition.
    Hutt DM; Roth DM; Vignaud H; Cullin C; Bouchecareilh M
    PLoS One; 2014; 9(8):e106224. PubMed ID: 25166596
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Glycogen synthase kinase 3 phosphorylates hypoxia-inducible factor 1alpha and mediates its destabilization in a VHL-independent manner.
    Flügel D; Görlach A; Michiels C; Kietzmann T
    Mol Cell Biol; 2007 May; 27(9):3253-65. PubMed ID: 17325032
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Newcastle disease virus degrades HIF-1α through proteasomal pathways independent of VHL and p53.
    Abd-Aziz N; Stanbridge EJ; Shafee N
    J Gen Virol; 2016 Dec; 97(12):3174-3182. PubMed ID: 27902314
    [TBL] [Abstract][Full Text] [Related]  

  • 15. HIF-1alpha and EPAS ubiquitination mediated by the VHL tumour suppressor involves flexibility in the ubiquitination mechanism, similar to other RING E3 ligases.
    Paltoglou S; Roberts BJ
    Oncogene; 2007 Jan; 26(4):604-9. PubMed ID: 16862177
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Down-regulation of HIF-1alpha by oncolytic reovirus infection independently of VHL and p53.
    Cho IR; Koh SS; Min HJ; Park EH; Ratakorn S; Jhun BH; Jeong SH; Yoo YH; Youn HD; Johnston RN; Chung YH
    Cancer Gene Ther; 2010 May; 17(5):365-72. PubMed ID: 20075985
    [TBL] [Abstract][Full Text] [Related]  

  • 17. RACK1 competes with HSP90 for binding to HIF-1alpha and is required for O(2)-independent and HSP90 inhibitor-induced degradation of HIF-1alpha.
    Liu YV; Baek JH; Zhang H; Diez R; Cole RN; Semenza GL
    Mol Cell; 2007 Jan; 25(2):207-17. PubMed ID: 17244529
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Estrogen receptor α is a novel target of the Von Hippel-Lindau protein and is responsible for the proliferation of VHL-deficient cells under hypoxic conditions.
    Jung YS; Lee SJ; Yoon MH; Ha NC; Park BJ
    Cell Cycle; 2012 Dec; 11(23):4462-73. PubMed ID: 23159849
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Class II histone deacetylases are associated with VHL-independent regulation of hypoxia-inducible factor 1 alpha.
    Qian DZ; Kachhap SK; Collis SJ; Verheul HM; Carducci MA; Atadja P; Pili R
    Cancer Res; 2006 Sep; 66(17):8814-21. PubMed ID: 16951198
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3'-kinase/Akt signaling pathway.
    Blancher C; Moore JW; Robertson N; Harris AL
    Cancer Res; 2001 Oct; 61(19):7349-55. PubMed ID: 11585776
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.