311 related articles for article (PubMed ID: 16509569)
1. Novel 1alpha,25-dihydroxyvitamin D3 analogues with the side chain at C12.
González-Avión XC; Mouriño A; Rochel N; Moras D
J Med Chem; 2006 Mar; 49(5):1509-16. PubMed ID: 16509569
[TBL] [Abstract][Full Text] [Related]
2. Crystal structures of the vitamin D nuclear receptor liganded with the vitamin D side chain analogues calcipotriol and seocalcitol, receptor agonists of clinical importance. Insights into a structural basis for the switching of calcipotriol to a receptor antagonist by further side chain modification.
Tocchini-Valentini G; Rochel N; Wurtz JM; Moras D
J Med Chem; 2004 Apr; 47(8):1956-61. PubMed ID: 15055995
[TBL] [Abstract][Full Text] [Related]
3. 22-Alkyl-20-epi-1alpha,25-dihydroxyvitamin D3 compounds of superagonistic activity: syntheses, biological activities and interaction with the receptor.
Yamamoto K; Inaba Y; Yoshimoto N; Choi M; DeLuca HF; Yamada S
J Med Chem; 2007 Mar; 50(5):932-9. PubMed ID: 17298045
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and biological activities of new 1alpha,25-dihydroxy-19-norvitamin D3 analogs with modifications in both the A-ring and the side chain.
Shimizu M; Miyamoto Y; Kobayashi E; Shimazaki M; Yamamoto K; Reischl W; Yamada S
Bioorg Med Chem; 2006 Jun; 14(12):4277-94. PubMed ID: 16503143
[TBL] [Abstract][Full Text] [Related]
5. Biological activity of CD-ring modified 1alpha,25-dihydroxyvitamin D analogues: C-ring and five-membered D-ring analogues.
Verstuyf A; Verlinden L; van Etten E; Shi L; Wu Y; D'Halleweyn C; Van Haver D; Zhu GD; Chen YJ; Zhou X; Haussler MR; De Clercq P; Vandewalle M; Van Baelen H; Mathieu C; Bouillon R
J Bone Miner Res; 2000 Feb; 15(2):237-52. PubMed ID: 10703925
[TBL] [Abstract][Full Text] [Related]
6. The first locked side-chain analogues of calcitriol (1alpha,25-dihydroxyvitamin D3) induce vitamin D receptor transcriptional activity.
Pérez-García X; Rumbo A; Larriba MJ; Ordóñez P; Muñoz A; Mouriño A
Org Lett; 2003 Oct; 5(22):4033-6. PubMed ID: 14572242
[TBL] [Abstract][Full Text] [Related]
7. Structural evaluation of the agonistic action of a vitamin D analog with two side chains binding to the nuclear vitamin D receptor.
Väisänen S; Peräkylä M; Kärkkäinen JI; Uskokovic MR; Carlberg C
Mol Pharmacol; 2003 Jun; 63(6):1230-7. PubMed ID: 12761332
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and structure-activity relationships of 16-ene-22-thia-1alpha,25-dihydroxy-26,27-dimethyl-19-norvitamin D3 analogs having side chains of different sizes.
Takaku H; Miyamoto Y; Asami S; Shimazaki M; Yamada S; Yamamoto K; Udagawa N; DeLuca HF; Shimizu M
Bioorg Med Chem; 2008 Feb; 16(4):1796-815. PubMed ID: 18032055
[TBL] [Abstract][Full Text] [Related]
9. Characterization of five 19-nor-analogs of 1alpha,25(OH)2-Vitamin D3 with 20-cyclopropyl-modified side-chains: implications for ligand binding and calcemic properties.
Olivera CJ; Bula CM; Bishop JE; Adorini L; Manchand P; Uskokovic MR; Norman AW
J Steroid Biochem Mol Biol; 2004 May; 89-90(1-5):99-106. PubMed ID: 15225754
[TBL] [Abstract][Full Text] [Related]
10. 25-Dehydro-1alpha-hydroxyvitamin D3-26,23S-lactone antagonizes the nuclear vitamin D receptor by mediating a unique noncovalent conformational change.
Bula CM; Bishop JE; Ishizuka S; Norman AW
Mol Endocrinol; 2000 Nov; 14(11):1788-96. PubMed ID: 11075812
[TBL] [Abstract][Full Text] [Related]
11. Vitamin D receptor ligands for osteoporosis.
Cheskis BJ; Freedman LP; Nagpal S
Curr Opin Investig Drugs; 2006 Oct; 7(10):906-11. PubMed ID: 17086935
[TBL] [Abstract][Full Text] [Related]
12. Asymmetric catalytic ene-cyclization approach to 2-fluoro-19-nor-1,25-dihydroxyvitamin D(3) A-ring analog with significant transactivation activity.
Mikami K; Ohba S; Ohmura H; Kubodera N; Nakagawa K; Okano T
Chirality; 2001 Jul; 13(7):366-71. PubMed ID: 11400190
[TBL] [Abstract][Full Text] [Related]
13. Potent antagonist for the vitamin D receptor: vitamin D analogues with simple side chain structure.
Sakamaki Y; Inaba Y; Yoshimoto N; Yamamoto K
J Med Chem; 2010 Aug; 53(15):5813-26. PubMed ID: 20608741
[TBL] [Abstract][Full Text] [Related]
14. New 2-alkylidene 1alpha,25-dihydroxy-19-norvitamin D3 analogues of high intestinal activity: synthesis and biological evaluation of 2-(3'-alkoxypropylidene) and 2-(3'-hydroxypropylidene) derivatives.
Glebocka A; Sicinski RR; Plum LA; Clagett-Dame M; DeLuca HF
J Med Chem; 2006 May; 49(10):2909-20. PubMed ID: 16686534
[TBL] [Abstract][Full Text] [Related]
15. The biological activity of nonsteroidal vitamin D hormone analogs lacking both the C- and D-rings.
Verstuyf A; Verlinden L; Van Baelen H; Sabbe K; D'Hallewyn C; De Clercq P; Vandewalle M; Bouillon R
J Bone Miner Res; 1998 Apr; 13(4):549-58. PubMed ID: 9556055
[TBL] [Abstract][Full Text] [Related]
16. Structure-activity relationships of 19-norvitamin D analogs having a fluoroethylidene group at the C-2 position.
Kobayashi E; Shimazaki M; Miyamoto Y; Masuno H; Yamamoto K; DeLuca HF; Yamada S; Shimizu M
Bioorg Med Chem; 2007 Feb; 15(3):1475-82. PubMed ID: 17110116
[TBL] [Abstract][Full Text] [Related]
17. Vitamin D receptor ligands: the impact of crystal structures.
Carlberg C; Molnár F; Mouriño A
Expert Opin Ther Pat; 2012 Apr; 22(4):417-35. PubMed ID: 22449247
[TBL] [Abstract][Full Text] [Related]
18. Functionalization at C-12 of 1alpha,25-dihydroxyvitamin D(3) strongly modulates the affinity for the vitamin D receptor (VDR).
González-Avión XC; Mouriño A
Org Lett; 2003 Jun; 5(13):2291-3. PubMed ID: 12816431
[TBL] [Abstract][Full Text] [Related]
19. Superagonistic action of 14-epi-analogs of 1,25-dihydroxyvitamin D explained by vitamin D receptor-coactivator interaction.
Eelen G; Verlinden L; Rochel N; Claessens F; De Clercq P; Vandewalle M; Tocchini-Valentini G; Moras D; Bouillon R; Verstuyf A
Mol Pharmacol; 2005 May; 67(5):1566-73. PubMed ID: 15728261
[TBL] [Abstract][Full Text] [Related]
20. Structural variants of the vitamin D analogue EB1089 reduce its ligand sensitivity and promoter selectivity.
Quack M; Clarin A; Binderup E; Björkling F; Hansen CM; Carlberg C
J Cell Biochem; 1998 Dec; 71(3):340-50. PubMed ID: 9831071
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
