151 related articles for article (PubMed ID: 16510597)
1. The small organic compound HA14-1 prevents Bcl-2 interaction with Bax to sensitize malignant glioma cells to induction of cell death.
Manero F; Gautier F; Gallenne T; Cauquil N; Grée D; Cartron PF; Geneste O; Grée R; Vallette FM; Juin P
Cancer Res; 2006 Mar; 66(5):2757-64. PubMed ID: 16510597
[TBL] [Abstract][Full Text] [Related]
2. Small inhibitor of Bcl-2, HA14-1, selectively enhanced the apoptotic effect of cisplatin by modulating Bcl-2 family members in MDA-MB-231 breast cancer cells.
Arisan ED; Kutuk O; Tezil T; Bodur C; Telci D; Basaga H
Breast Cancer Res Treat; 2010 Jan; 119(2):271-81. PubMed ID: 19238538
[TBL] [Abstract][Full Text] [Related]
3. Structure-activity relationship studies of ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (HA 14-1), an antagonist for antiapoptotic Bcl-2 proteins to overcome drug resistance in cancer.
Doshi JM; Tian D; Xing C
J Med Chem; 2006 Dec; 49(26):7731-9. PubMed ID: 17181155
[TBL] [Abstract][Full Text] [Related]
4. Bcl-2 inhibitors induce apoptosis in chronic lymphocytic leukemia cells.
Campàs C; Cosialls AM; Barragán M; Iglesias-Serret D; Santidrián AF; Coll-Mulet L; de Frias M; Domingo A; Pons G; Gil J
Exp Hematol; 2006 Dec; 34(12):1663-9. PubMed ID: 17157163
[TBL] [Abstract][Full Text] [Related]
5. Overcoming the radioresistance of prostate cancer cells with a novel Bcl-2 inhibitor.
An J; Chervin AS; Nie A; Ducoff HS; Huang Z
Oncogene; 2007 Feb; 26(5):652-61. PubMed ID: 16909121
[TBL] [Abstract][Full Text] [Related]
6. Apoptosis-based treatment of glioblastomas with ABT-737, a novel small molecule inhibitor of Bcl-2 family proteins.
Tagscherer KE; Fassl A; Campos B; Farhadi M; Kraemer A; Böck BC; Macher-Goeppinger S; Radlwimmer B; Wiestler OD; Herold-Mende C; Roth W
Oncogene; 2008 Nov; 27(52):6646-56. PubMed ID: 18663354
[TBL] [Abstract][Full Text] [Related]
7. Ethyl-2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H- chromene-3-carboxylate (HA 14-1), a prototype small-molecule antagonist against antiapoptotic Bcl-2 proteins, decomposes to generate reactive oxygen species that induce apoptosis.
Doshi JM; Tian D; Xing C
Mol Pharm; 2007; 4(6):919-28. PubMed ID: 17874842
[TBL] [Abstract][Full Text] [Related]
8. Effects of selective Bcl-2 inhibitor HA14-1 treatments on functional activity of magnocellular vasopressinergic neurons of rat hypothalamus.
Chernigovskaya EV; Nikitina LS; Dorofeeva NA; Glazova MV
Neurosci Lett; 2008 May; 437(1):59-64. PubMed ID: 18434013
[TBL] [Abstract][Full Text] [Related]
9. Multiparametric analysis of HA14-1-induced apoptosis in follicular lymphoma cells.
Wlodkowic D; Skommer J; Pelkonen J
Leuk Res; 2006 Sep; 30(9):1187-92. PubMed ID: 16414117
[TBL] [Abstract][Full Text] [Related]
10. The Bcl-2/Bcl-XL family inhibitor ABT-737 sensitizes ovarian cancer cells to carboplatin.
Witham J; Valenti MR; De-Haven-Brandon AK; Vidot S; Eccles SA; Kaye SB; Richardson A
Clin Cancer Res; 2007 Dec; 13(23):7191-8. PubMed ID: 18056200
[TBL] [Abstract][Full Text] [Related]
11. Naringenin-induced apoptosis is attenuated by Bcl-2 but restored by the small molecule Bcl-2 inhibitor, HA 14-1, in human leukemia U937 cells.
Jin CY; Park C; Lee JH; Chung KT; Kwon TK; Kim GY; Choi BT; Choi YH
Toxicol In Vitro; 2009 Mar; 23(2):259-65. PubMed ID: 19124070
[TBL] [Abstract][Full Text] [Related]
12. Effect of HA14-1 on apoptosis-regulating proteins in HeLa cells.
Rehman K; Tariq M; Akash MS; Gillani Z; Qazi MH
Chem Biol Drug Des; 2014 Mar; 83(3):317-23. PubMed ID: 24118733
[TBL] [Abstract][Full Text] [Related]
13. HA14-1, a small molecule inhibitor of Bcl-2, bypasses chemoresistance in leukaemia cells.
Oliver L; Mahé B; Gréé R; Vallette FM; Juin P
Leuk Res; 2007 Jun; 31(6):859-63. PubMed ID: 17224180
[TBL] [Abstract][Full Text] [Related]
14. Preclinical studies of TW-37, a new nonpeptidic small-molecule inhibitor of Bcl-2, in diffuse large cell lymphoma xenograft model reveal drug action on both Bcl-2 and Mcl-1.
Mohammad RM; Goustin AS; Aboukameel A; Chen B; Banerjee S; Wang G; Nikolovska-Coleska Z; Wang S; Al-Katib A
Clin Cancer Res; 2007 Apr; 13(7):2226-35. PubMed ID: 17404107
[TBL] [Abstract][Full Text] [Related]
15. Combined proteasome and Bcl-2 inhibition stimulates apoptosis and inhibits growth in EBV-transformed lymphocytes: a potential therapeutic approach to EBV-associated lymphoproliferative diseases.
Srimatkandada P; Loomis R; Carbone R; Srimatkandada S; Lacy J
Eur J Haematol; 2008 May; 80(5):407-18. PubMed ID: 18221384
[TBL] [Abstract][Full Text] [Related]
16. HA14-1 selectively induces apoptosis in Bcl-2-overexpressing leukemia/lymphoma cells, and enhances cytarabine-induced cell death.
Lickliter JD; Wood NJ; Johnson L; McHugh G; Tan J; Wood F; Cox J; Wickham NW
Leukemia; 2003 Nov; 17(11):2074-80. PubMed ID: 12931228
[TBL] [Abstract][Full Text] [Related]
17. A novel BH3 mimetic reveals a mitogen-activated protein kinase-dependent mechanism of melanoma cell death controlled by p53 and reactive oxygen species.
Verhaegen M; Bauer JA; Martín de la Vega C; Wang G; Wolter KG; Brenner JC; Nikolovska-Coleska Z; Bengtson A; Nair R; Elder JT; Van Brocklin M; Carey TE; Bradford CR; Wang S; Soengas MS
Cancer Res; 2006 Dec; 66(23):11348-59. PubMed ID: 17145881
[TBL] [Abstract][Full Text] [Related]
18. Synergistic inhibition of breast cancer cell lines with a dual inhibitor of EGFR-HER-2/neu and a Bcl-2 inhibitor.
Witters LM; Witkoski A; Planas-Silva MD; Berger M; Viallet J; Lipton A
Oncol Rep; 2007 Feb; 17(2):465-9. PubMed ID: 17203189
[TBL] [Abstract][Full Text] [Related]
19. Critical upstream signals of cytochrome C release induced by a novel Bcl-2 inhibitor.
An J; Chen Y; Huang Z
J Biol Chem; 2004 Apr; 279(18):19133-40. PubMed ID: 14966123
[TBL] [Abstract][Full Text] [Related]
20. Apoptotic response to photodynamic therapy versus the Bcl-2 antagonist HA14-1.
Kessel D; Castelli M; Reiners JJ
Photochem Photobiol; 2002 Sep; 76(3):314-9. PubMed ID: 12403453
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]