131 related articles for article (PubMed ID: 16517756)
1. IkappaB kinase-2-independent and -dependent inflammation in airway disease models: relevance of IKK-2 inhibition to the clinic.
Birrell MA; Wong S; Hardaker EL; Catley MC; McCluskie K; Collins M; Haj-Yahia S; Belvisi MG
Mol Pharmacol; 2006 Jun; 69(6):1791-800. PubMed ID: 16517756
[TBL] [Abstract][Full Text] [Related]
2. Inhibition by a selective IkappaB kinase-2 inhibitor of interleukin-1-induced collagen degradation by corneal fibroblasts in three-dimensional culture.
Kondo Y; Fukuda K; Adachi T; Nishida T
Invest Ophthalmol Vis Sci; 2008 Nov; 49(11):4850-7. PubMed ID: 18676628
[TBL] [Abstract][Full Text] [Related]
3. Magnolol suppresses NF-kappaB activation and NF-kappaB regulated gene expression through inhibition of IkappaB kinase activation.
Tse AK; Wan CK; Zhu GY; Shen XL; Cheung HY; Yang M; Fong WF
Mol Immunol; 2007 Apr; 44(10):2647-58. PubMed ID: 17240450
[TBL] [Abstract][Full Text] [Related]
4. Validation of the anti-inflammatory properties of small-molecule IkappaB Kinase (IKK)-2 inhibitors by comparison with adenoviral-mediated delivery of dominant-negative IKK1 and IKK2 in human airways smooth muscle.
Catley MC; Sukkar MB; Chung KF; Jaffee B; Liao SM; Coyle AJ; Haddad el-B; Barnes PJ; Newton R
Mol Pharmacol; 2006 Aug; 70(2):697-705. PubMed ID: 16687566
[TBL] [Abstract][Full Text] [Related]
5. A selective small molecule IkappaB Kinase beta inhibitor blocks nuclear factor kappaB-mediated inflammatory responses in human fibroblast-like synoviocytes, chondrocytes, and mast cells.
Wen D; Nong Y; Morgan JG; Gangurde P; Bielecki A; Dasilva J; Keaveney M; Cheng H; Fraser C; Schopf L; Hepperle M; Harriman G; Jaffee BD; Ocain TD; Xu Y
J Pharmacol Exp Ther; 2006 Jun; 317(3):989-1001. PubMed ID: 16525037
[TBL] [Abstract][Full Text] [Related]
6. Repression of inflammatory gene expression in human pulmonary epithelial cells by small-molecule IkappaB kinase inhibitors.
Newton R; Holden NS; Catley MC; Oyelusi W; Leigh R; Proud D; Barnes PJ
J Pharmacol Exp Ther; 2007 May; 321(2):734-42. PubMed ID: 17322026
[TBL] [Abstract][Full Text] [Related]
7. A novel, highly selective, tight binding IkappaB kinase-2 (IKK-2) inhibitor: a tool to correlate IKK-2 activity to the fate and functions of the components of the nuclear factor-kappaB pathway in arthritis-relevant cells and animal models.
Mbalaviele G; Sommers CD; Bonar SL; Mathialagan S; Schindler JF; Guzova JA; Shaffer AF; Melton MA; Christine LJ; Tripp CS; Chiang PC; Thompson DC; Hu Y; Kishore N
J Pharmacol Exp Ther; 2009 Apr; 329(1):14-25. PubMed ID: 19168710
[TBL] [Abstract][Full Text] [Related]
8. Inflammatory NF-kappaB activation promotes hepatic apolipoprotein B100 secretion: evidence for a link between hepatic inflammation and lipoprotein production.
Tsai J; Zhang R; Qiu W; Su Q; Naples M; Adeli K
Am J Physiol Gastrointest Liver Physiol; 2009 Jun; 296(6):G1287-98. PubMed ID: 19342510
[TBL] [Abstract][Full Text] [Related]
9. Ikappa-B kinase-2 inhibitor blocks inflammation in human airway smooth muscle and a rat model of asthma.
Birrell MA; Hardaker E; Wong S; McCluskie K; Catley M; De Alba J; Newton R; Haj-Yahia S; Pun KT; Watts CJ; Shaw RJ; Savage TJ; Belvisi MG
Am J Respir Crit Care Med; 2005 Oct; 172(8):962-71. PubMed ID: 16002568
[TBL] [Abstract][Full Text] [Related]
10. Lipopolysaccharide and TNF-alpha activate the nuclear factor kappa B pathway in the human placental JEG-3 cells.
Lappas M; Yee K; Permezel M; Rice GE
Placenta; 2006; 27(6-7):568-75. PubMed ID: 16122789
[TBL] [Abstract][Full Text] [Related]
11. Role of matrix metalloproteinases in the inflammatory response in human airway cell-based assays and in rodent models of airway disease.
Birrell MA; Wong S; Dekkak A; De Alba J; Haj-Yahia S; Belvisi MG
J Pharmacol Exp Ther; 2006 Aug; 318(2):741-50. PubMed ID: 16690722
[TBL] [Abstract][Full Text] [Related]
12. Tumor necrosis factor-alpha regulates inflammatory and mesenchymal responses via mitogen-activated protein kinase kinase, p38, and nuclear factor kappaB in human endometriotic epithelial cells.
Grund EM; Kagan D; Tran CA; Zeitvogel A; Starzinski-Powitz A; Nataraja S; Palmer SS
Mol Pharmacol; 2008 May; 73(5):1394-404. PubMed ID: 18252806
[TBL] [Abstract][Full Text] [Related]
13. Regulation and function of IKK and IKK-related kinases.
Häcker H; Karin M
Sci STKE; 2006 Oct; 2006(357):re13. PubMed ID: 17047224
[TBL] [Abstract][Full Text] [Related]
14. Artemisolide is a typical inhibitor of IkappaB kinase beta targeting cysteine-179 residue and down-regulates NF-kappaB-dependent TNF-alpha expression in LPS-activated macrophages.
Kim BH; Lee JY; Seo JH; Lee HY; Ryu SY; Ahn BW; Lee CK; Hwang BY; Han SB; Kim Y
Biochem Biophys Res Commun; 2007 Sep; 361(3):593-8. PubMed ID: 17669364
[TBL] [Abstract][Full Text] [Related]
15. Role of IKK and ERK pathways in intrinsic inflammation of cystic fibrosis airways.
Verhaeghe C; Remouchamps C; Hennuy B; Vanderplasschen A; Chariot A; Tabruyn SP; Oury C; Bours V
Biochem Pharmacol; 2007 Jun; 73(12):1982-94. PubMed ID: 17466952
[TBL] [Abstract][Full Text] [Related]
16. Licochalcone A potently inhibits tumor necrosis factor alpha-induced nuclear factor-kappaB activation through the direct inhibition of IkappaB kinase complex activation.
Funakoshi-Tago M; Tanabe S; Tago K; Itoh H; Mashino T; Sonoda Y; Kasahara T
Mol Pharmacol; 2009 Oct; 76(4):745-53. PubMed ID: 19592502
[TBL] [Abstract][Full Text] [Related]
17. Histone deacetylase inhibitors suppress the inducibility of nuclear factor-kappaB by tumor necrosis factor-alpha receptor-1 down-regulation.
Imre G; Gekeler V; Leja A; Beckers T; Boehm M
Cancer Res; 2006 May; 66(10):5409-18. PubMed ID: 16707469
[TBL] [Abstract][Full Text] [Related]
18. Attenuation of murine collagen-induced arthritis by a novel, potent, selective small molecule inhibitor of IkappaB Kinase 2, TPCA-1 (2-[(aminocarbonyl)amino]-5-(4-fluorophenyl)-3-thiophenecarboxamide), occurs via reduction of proinflammatory cytokines and antigen-induced T cell Proliferation.
Podolin PL; Callahan JF; Bolognese BJ; Li YH; Carlson K; Davis TG; Mellor GW; Evans C; Roshak AK
J Pharmacol Exp Ther; 2005 Jan; 312(1):373-81. PubMed ID: 15316093
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of aldose reductase prevents lipopolysaccharide-induced inflammatory response in human lens epithelial cells.
Pladzyk A; Reddy AB; Yadav UC; Tammali R; Ramana KV; Srivastava SK
Invest Ophthalmol Vis Sci; 2006 Dec; 47(12):5395-403. PubMed ID: 17122129
[TBL] [Abstract][Full Text] [Related]
20. Use of molecular imaging to quantify response to IKK-2 inhibitor treatment in murine arthritis.
Izmailova ES; Paz N; Alencar H; Chun M; Schopf L; Hepperle M; Lane JH; Harriman G; Xu Y; Ocain T; Weissleder R; Mahmood U; Healy AM; Jaffee B
Arthritis Rheum; 2007 Jan; 56(1):117-28. PubMed ID: 17195214
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
