120 related articles for article (PubMed ID: 16517984)
1. Ligand-induced effects on pyruvate dehydrogenase kinase isoform 2.
Hiromasa Y; Hu L; Roche TE
J Biol Chem; 2006 May; 281(18):12568-79. PubMed ID: 16517984
[TBL] [Abstract][Full Text] [Related]
2. Specific ion influences on self-association of pyruvate dehydrogenase kinase isoform 2 (PDHK2), binding of PDHK2 to the L2 lipoyl domain, and effects of the lipoyl group-binding site inhibitor, Nov3r.
Hiromasa Y; Yan X; Roche TE
Biochemistry; 2008 Feb; 47(8):2312-24. PubMed ID: 18220415
[TBL] [Abstract][Full Text] [Related]
3. Critical role of specific ions for ligand-induced changes regulating pyruvate dehydrogenase kinase isoform 2.
Hiromasa Y; Roche TE
Biochemistry; 2008 Feb; 47(8):2298-311. PubMed ID: 18220414
[TBL] [Abstract][Full Text] [Related]
4. Facilitated interaction between the pyruvate dehydrogenase kinase isoform 2 and the dihydrolipoyl acetyltransferase.
Hiromasa Y; Roche TE
J Biol Chem; 2003 Sep; 278(36):33681-93. PubMed ID: 12816949
[TBL] [Abstract][Full Text] [Related]
5. Structural determinants for cross-talk between pyruvate dehydrogenase kinase 3 and lipoyl domain 2 of the human pyruvate dehydrogenase complex.
Tso SC; Kato M; Chuang JL; Chuang DT
J Biol Chem; 2006 Sep; 281(37):27197-204. PubMed ID: 16849321
[TBL] [Abstract][Full Text] [Related]
6. Structural and functional insights into the molecular mechanisms responsible for the regulation of pyruvate dehydrogenase kinase 2.
Green T; Grigorian A; Klyuyeva A; Tuganova A; Luo M; Popov KM
J Biol Chem; 2008 Jun; 283(23):15789-98. PubMed ID: 18387944
[TBL] [Abstract][Full Text] [Related]
7. Pyruvate dehydrogenase kinase isoform 2 activity limited and further inhibited by slowing down the rate of dissociation of ADP.
Bao H; Kasten SA; Yan X; Roche TE
Biochemistry; 2004 Oct; 43(42):13432-41. PubMed ID: 15491150
[TBL] [Abstract][Full Text] [Related]
8. Recognition of the inner lipoyl-bearing domain of dihydrolipoyl transacetylase and of the blood glucose-lowering compound AZD7545 by pyruvate dehydrogenase kinase 2.
Tuganova A; Klyuyeva A; Popov KM
Biochemistry; 2007 Jul; 46(29):8592-602. PubMed ID: 17602666
[TBL] [Abstract][Full Text] [Related]
9. Marked differences between two isoforms of human pyruvate dehydrogenase kinase.
Baker JC; Yan X; Peng T; Kasten S; Roche TE
J Biol Chem; 2000 May; 275(21):15773-81. PubMed ID: 10748134
[TBL] [Abstract][Full Text] [Related]
10. Pyruvate dehydrogenase kinase isoform 2 activity stimulated by speeding up the rate of dissociation of ADP.
Bao H; Kasten SA; Yan X; Hiromasa Y; Roche TE
Biochemistry; 2004 Oct; 43(42):13442-51. PubMed ID: 15491151
[TBL] [Abstract][Full Text] [Related]
11. Binding of the pyruvate dehydrogenase kinase to recombinant constructs containing the inner lipoyl domain of the dihydrolipoyl acetyltransferase component.
Liu S; Baker JC; Roche TE
J Biol Chem; 1995 Jan; 270(2):793-800. PubMed ID: 7822313
[TBL] [Abstract][Full Text] [Related]
12. Lipoyl domain-based mechanism for the integrated feedback control of the pyruvate dehydrogenase complex by enhancement of pyruvate dehydrogenase kinase activity.
Ravindran S; Radke GA; Guest JR; Roche TE
J Biol Chem; 1996 Jan; 271(2):653-62. PubMed ID: 8557670
[TBL] [Abstract][Full Text] [Related]
13. Allosteric coupling in pyruvate dehydrogenase kinase 2.
Klyuyeva A; Tuganova A; Popov KM
Biochemistry; 2008 Aug; 47(32):8358-66. PubMed ID: 18627174
[TBL] [Abstract][Full Text] [Related]
14. Regulatory roles of the N-terminal domain based on crystal structures of human pyruvate dehydrogenase kinase 2 containing physiological and synthetic ligands.
Knoechel TR; Tucker AD; Robinson CM; Phillips C; Taylor W; Bungay PJ; Kasten SA; Roche TE; Brown DG
Biochemistry; 2006 Jan; 45(2):402-15. PubMed ID: 16401071
[TBL] [Abstract][Full Text] [Related]
15. The catalytic requirements for reduction and acetylation of protein X and the related regulation of various forms of resolved pyruvate dehydrogenase kinase.
Rahmatullah M; Roche TE
J Biol Chem; 1987 Jul; 262(21):10265-71. PubMed ID: 3611060
[TBL] [Abstract][Full Text] [Related]
16. Requirements for the adaptor protein role of dihydrolipoyl acetyltransferase in the up-regulated function of the pyruvate dehydrogenase kinase and pyruvate dehydrogenase phosphatase.
Yang D; Gong X; Yakhnin A; Roche TE
J Biol Chem; 1998 Jun; 273(23):14130-7. PubMed ID: 9603912
[TBL] [Abstract][Full Text] [Related]
17. Crystal structure of pyruvate dehydrogenase kinase 3 bound to lipoyl domain 2 of human pyruvate dehydrogenase complex.
Kato M; Chuang JL; Tso SC; Wynn RM; Chuang DT
EMBO J; 2005 May; 24(10):1763-74. PubMed ID: 15861126
[TBL] [Abstract][Full Text] [Related]
18. Activated function of the pyruvate dehydrogenase phosphatase through Ca2+-facilitated binding to the inner lipoyl domain of the dihydrolipoyl acetyltransferase.
Chen G; Wang L; Liu S; Chuang C; Roche TE
J Biol Chem; 1996 Nov; 271(45):28064-70. PubMed ID: 8910418
[TBL] [Abstract][Full Text] [Related]
19. Interaction between the individual isoenzymes of pyruvate dehydrogenase kinase and the inner lipoyl-bearing domain of transacetylase component of pyruvate dehydrogenase complex.
Tuganova A; Boulatnikov I; Popov KM
Biochem J; 2002 Aug; 366(Pt 1):129-36. PubMed ID: 11978179
[TBL] [Abstract][Full Text] [Related]
20. Pyruvate dehydrogenase kinase regulatory mechanisms and inhibition in treating diabetes, heart ischemia, and cancer.
Roche TE; Hiromasa Y
Cell Mol Life Sci; 2007 Apr; 64(7-8):830-49. PubMed ID: 17310282
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
