These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

105 related articles for article (PubMed ID: 1651809)

  • 21. Differential activation of cyclophosphamide and ifosphamide by cytochromes P-450 2B and 3A in human liver microsomes.
    Chang TK; Weber GF; Crespi CL; Waxman DJ
    Cancer Res; 1993 Dec; 53(23):5629-37. PubMed ID: 8242617
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Rabbit cytochrome P450 4B1: A novel prodrug activating gene for pharmacogene therapy of hepatocellular carcinoma.
    Mohr L; Rainov NG; Mohr UG; Wands JR
    Cancer Gene Ther; 2000 Jul; 7(7):1008-14. PubMed ID: 10917203
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Estradiol metabolism by complementary deoxyribonucleic acid-expressed human cytochrome P450s.
    Aoyama T; Korzekwa K; Nagata K; Gillette J; Gelboin HV; Gonzalez FJ
    Endocrinology; 1990 Jun; 126(6):3101-6. PubMed ID: 2161748
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Identification of amino acid determinants in CYP4B1 for optimal catalytic processing of 4-ipomeanol.
    Wiek C; Schmidt EM; Roellecke K; Freund M; Nakano M; Kelly EJ; Kaisers W; Yarov-Yarovoy V; Kramm CM; Rettie AE; Hanenberg H
    Biochem J; 2015 Jan; 465(1):103-14. PubMed ID: 25247810
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Mutagenic activation of 2-amino-3-methylimidazo[4,5-f]quinoline by complementary DNA-expressed human liver P-450.
    Aoyama T; Gelboin HV; Gonzalez FJ
    Cancer Res; 1990 Apr; 50(7):2060-3. PubMed ID: 2180561
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Metabolism of (R)-(+)-pulegone and (R)-(+)-menthofuran by human liver cytochrome P-450s: evidence for formation of a furan epoxide.
    Khojasteh-Bakht SC; Chen W; Koenigs LL; Peter RM; Nelson SD
    Drug Metab Dispos; 1999 May; 27(5):574-80. PubMed ID: 10220485
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Biotransformation of coumarin by rodent and human cytochromes P-450: metabolic basis of tissue-selective toxicity in olfactory mucosa of rats and mice.
    Zhuo X; Gu J; Zhang QY; Spink DC; Kaminsky LS; Ding X
    J Pharmacol Exp Ther; 1999 Feb; 288(2):463-71. PubMed ID: 9918546
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Specificity of cDNA-expressed human and rodent cytochrome P450s in the oxidative metabolism of the potent carcinogen 7,12-dimethylbenz[a]anthracene.
    Shou M; Korzekwa KR; Krausz KW; Buters JT; Grogan J; Goldfarb I; Hardwick JP; Gonzalez FJ; Gelboin HV
    Mol Carcinog; 1996 Dec; 17(4):241-9. PubMed ID: 8989918
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The in vitro formation of glutathione conjugates with the microsomally activated pulmonary bronchiolar aklylating agent and cytotoxin, 4-ipomeanol.
    Buckpitt AR; Boyd MR
    J Pharmacol Exp Ther; 1980 Oct; 215(1):97-103. PubMed ID: 7452496
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Protective role of endogenous pulmonary glutathione and other sulfhydryl compounds against lung damage by alkylating agents. Investigations with 4-ipomeanol in the rat.
    Boyd MR; Stiko A; Statham CN; Jones RB
    Biochem Pharmacol; 1982 Apr; 31(8):1579-83. PubMed ID: 7092947
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Metabolism of 3-methylindole by vaccinia-expressed P450 enzymes: correlation of 3-methyleneindolenine formation and protein-binding.
    Thornton-Manning J; Appleton ML; Gonzalez FJ; Yost GS
    J Pharmacol Exp Ther; 1996 Jan; 276(1):21-9. PubMed ID: 8558432
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Biotransformation of parathion in human liver: participation of CYP3A4 and its inactivation during microsomal parathion oxidation.
    Butler AM; Murray M
    J Pharmacol Exp Ther; 1997 Feb; 280(2):966-73. PubMed ID: 9023313
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Mapping of cytochrome P-450 distribution and function with monoclonal antibodies and cDNA expression.
    Gelboin HV; Park SS; Aoyama T; Fujino T; Crespi CL; Gonzalez FJ
    Princess Takamatsu Symp; 1990; 21():3-16. PubMed ID: 2134683
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Cytochrome P-450 3A and 2D6 catalyze ortho hydroxylation of 4-hydroxytamoxifen and 3-hydroxytamoxifen (droloxifene) yielding tamoxifen catechol: involvement of catechols in covalent binding to hepatic proteins.
    Dehal SS; Kupfer D
    Drug Metab Dispos; 1999 Jun; 27(6):681-8. PubMed ID: 10348797
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Mechanism-based inactivation of cytochrome P450 3A4 by 4-ipomeanol.
    Alvarez-Diez TM; Zheng J
    Chem Res Toxicol; 2004 Feb; 17(2):150-7. PubMed ID: 14967002
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Development of a substrate-activity based approach to identify the major human liver P-450 catalysts of cyclophosphamide and ifosfamide activation based on cDNA-expressed activities and liver microsomal P-450 profiles.
    Roy P; Yu LJ; Crespi CL; Waxman DJ
    Drug Metab Dispos; 1999 Jun; 27(6):655-66. PubMed ID: 10348794
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Detection of glutathione conjugates derived from 4-ipomeanol metabolism in bile of rats by liquid chromatography-tandem mass spectrometry.
    Alvarez-Diez TM; Zheng J
    Drug Metab Dispos; 2004 Dec; 32(12):1345-50. PubMed ID: 15328249
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Renal toxicity due to reactive metabolites formed in situ in the kidney: investigations with 4-ipomeanol in the mouse.
    Boyd MR; Dutcher JS
    J Pharmacol Exp Ther; 1981 Mar; 216(3):640-6. PubMed ID: 7205642
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Role of human cytochrome P-450s in risk assessment and susceptibility to environmentally based disease.
    Gonzalez FJ; Gelboin HV
    J Toxicol Environ Health; 1993; 40(2-3):289-308. PubMed ID: 8230303
    [TBL] [Abstract][Full Text] [Related]  

  • 40. The kinetics of aflatoxin B1 oxidation by human cDNA-expressed and human liver microsomal cytochromes P450 1A2 and 3A4.
    Gallagher EP; Kunze KL; Stapleton PL; Eaton DL
    Toxicol Appl Pharmacol; 1996 Dec; 141(2):595-606. PubMed ID: 8975785
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.