These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

100 related articles for article (PubMed ID: 16519515)

  • 1. Molecular dynamics simulations of arachidonic acid-derived pentadienyl radical intermediate complexes with COX-1 and COX-2: insights into oxygenation regio- and stereoselectivity.
    Furse KE; Pratt DA; Schneider C; Brash AR; Porter NA; Lybrand TP
    Biochemistry; 2006 Mar; 45(10):3206-18. PubMed ID: 16519515
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular dynamics simulations of arachidonic acid complexes with COX-1 and COX-2: insights into equilibrium behavior.
    Furse KE; Pratt DA; Porter NA; Lybrand TP
    Biochemistry; 2006 Mar; 45(10):3189-205. PubMed ID: 16519514
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regio- and stereospecificity in the oxygenation of arachidonic acid catalyzed by Leu597 mutants of rabbit 15-lipoxygenase: a QM/MM study.
    Suardíaz R; Masgrau L; Lluch JM; González-Lafont A
    Chemphyschem; 2014 Aug; 15(11):2303-10. PubMed ID: 24753045
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural comparisons of arachidonic acid-induced radicals formed by prostaglandin H synthase-1 and -2.
    Tsai AL; Wu G; Rogge CE; Lü JM; Peng S; van der Donk WA; Palmer G; Gerfen GJ; Kulmacz RJ
    J Inorg Biochem; 2011 Mar; 105(3):366-74. PubMed ID: 21421123
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A mechanistic hypothesis for the aspirin-induced switch in lipid mediator production by cyclooxygenase-2.
    Tosco P
    J Am Chem Soc; 2013 Jul; 135(28):10404-10. PubMed ID: 23786234
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Arg-513 and Leu-531 Are Key Residues Governing Time-Dependent Inhibition of Cyclooxygenase-2 by Aspirin and Celebrex.
    Dong L; Anderson AJ; Malkowski MG
    Biochemistry; 2019 Sep; 58(38):3990-4002. PubMed ID: 31469551
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Partnering between monomers of cyclooxygenase-2 homodimers.
    Yuan C; Rieke CJ; Rimon G; Wingerd BA; Smith WL
    Proc Natl Acad Sci U S A; 2006 Apr; 103(16):6142-7. PubMed ID: 16606823
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The structure of mammalian cyclooxygenases.
    Garavito RM; Mulichak AM
    Annu Rev Biophys Biomol Struct; 2003; 32():183-206. PubMed ID: 12574066
    [TBL] [Abstract][Full Text] [Related]  

  • 9. On the regio- and stereospecificity of arachidonic acid peroxidation catalyzed by mammalian 15-lypoxygenases: a combined molecular dynamics and QM/MM study.
    Suardíaz R; Masgrau L; Lluch JM; González-Lafont A
    Chemphyschem; 2013 Nov; 14(16):3777-87. PubMed ID: 24115233
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural insights into the stereochemistry of the cyclooxygenase reaction.
    Kiefer JR; Pawlitz JL; Moreland KT; Stegeman RA; Hood WF; Gierse JK; Stevens AM; Goodwin DC; Rowlinson SW; Marnett LJ; Stallings WC; Kurumbail RG
    Nature; 2000 May; 405(6782):97-101. PubMed ID: 10811226
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular oxygen dependent steps in fatty acid oxidation by cyclooxygenase-1.
    Mukherjee A; Brinkley DW; Chang KM; Roth JP
    Biochemistry; 2007 Apr; 46(13):3975-89. PubMed ID: 17355126
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural basis of fatty acid substrate binding to cyclooxygenase-2.
    Vecchio AJ; Simmons DM; Malkowski MG
    J Biol Chem; 2010 Jul; 285(29):22152-63. PubMed ID: 20463020
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A comparative study of the COX-1 and COX-2 isozymes bound to lipid membranes.
    Wan S; Coveney PV
    J Comput Chem; 2009 May; 30(7):1038-50. PubMed ID: 18942723
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Investigating substrate promiscuity in cyclooxygenase-2: the role of Arg-120 and residues lining the hydrophobic groove.
    Vecchio AJ; Orlando BJ; Nandagiri R; Malkowski MG
    J Biol Chem; 2012 Jul; 287(29):24619-30. PubMed ID: 22637474
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural modeling and simulation studies of human cyclooxygenase (COX) isozymes with selected terpenes: implications in drug designing and development.
    Singh S; Pandey VP; Naaz H; Singh P; Dwivedi UN
    Comput Biol Med; 2013 Jul; 43(6):744-50. PubMed ID: 23668350
    [TBL] [Abstract][Full Text] [Related]  

  • 16. New evidence of H1-receptor independent COX-2 inhibition by fexofenadine HCl in vitro.
    Juergens UR; Gillissen A; Uen S; Racké K; Stöber M; Darlath W; Vetter H
    Pharmacology; 2006; 78(3):129-35. PubMed ID: 17016062
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Conformational effects on the pro-S hydrogen abstraction reaction in cyclooxygenase-1: an integrated QM/MM and MD study.
    Christov CZ; Lodola A; Karabencheva-Christova TG; Wan S; Coveney PV; Mulholland AJ
    Biophys J; 2013 Mar; 104(5):L5-7. PubMed ID: 23473504
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dynamics of Radical Intermediates in Prostaglandin H Synthase-1 Cyclooxygenase Reactions is Modulated by Multiple Factors.
    Wu G; Tsai AL
    Protein Pept Lett; 2016; 23(11):1013-1023. PubMed ID: 27748183
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of Tyr348 in Tyr385 radical dynamics and cyclooxygenase inhibitor interactions in prostaglandin H synthase-2.
    Rogge CE; Ho B; Liu W; Kulmacz RJ; Tsai AL
    Biochemistry; 2006 Jan; 45(2):523-32. PubMed ID: 16401081
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Analysis of hydroperoxide-induced tyrosyl radicals and lipoxygenase activity in aspirin-treated human prostaglandin H synthase-2.
    Xiao G; Tsai AL; Palmer G; Boyar WC; Marshall PJ; Kulmacz RJ
    Biochemistry; 1997 Feb; 36(7):1836-45. PubMed ID: 9048568
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.