183 related articles for article (PubMed ID: 16530014)
1. LKB1: a sweet side to Peutz-Jeghers syndrome?
Carling D
Trends Mol Med; 2006 Apr; 12(4):144-7. PubMed ID: 16530014
[TBL] [Abstract][Full Text] [Related]
2. Metformin inhibits hepatic gluconeogenesis through AMP-activated protein kinase-dependent regulation of the orphan nuclear receptor SHP.
Kim YD; Park KG; Lee YS; Park YY; Kim DK; Nedumaran B; Jang WG; Cho WJ; Ha J; Lee IK; Lee CH; Choi HS
Diabetes; 2008 Feb; 57(2):306-14. PubMed ID: 17909097
[TBL] [Abstract][Full Text] [Related]
3. [From cancer to diabetes treatment : the tumor suppressor LKB1 as a new pharmacological target].
Foretz M; Guigas B; Viollet B
Med Sci (Paris); 2006 Apr; 22(4):348-50. PubMed ID: 16597397
[No Abstract] [Full Text] [Related]
4. Functional analysis of Peutz-Jeghers mutations reveals that the LKB1 C-terminal region exerts a crucial role in regulating both the AMPK pathway and the cell polarity.
Forcet C; Etienne-Manneville S; Gaude H; Fournier L; Debilly S; Salmi M; Baas A; Olschwang S; Clevers H; Billaud M
Hum Mol Genet; 2005 May; 14(10):1283-92. PubMed ID: 15800014
[TBL] [Abstract][Full Text] [Related]
5. LKB1 and AMPK family signaling: the intimate link between cell polarity and energy metabolism.
Jansen M; Ten Klooster JP; Offerhaus GJ; Clevers H
Physiol Rev; 2009 Jul; 89(3):777-98. PubMed ID: 19584313
[TBL] [Abstract][Full Text] [Related]
6. Dysfunctional AMPK activity, signalling through mTOR and survival in response to energetic stress in LKB1-deficient lung cancer.
Carretero J; Medina PP; Blanco R; Smit L; Tang M; Roncador G; Maestre L; Conde E; Lopez-Rios F; Clevers HC; Sanchez-Cespedes M
Oncogene; 2007 Mar; 26(11):1616-25. PubMed ID: 16953221
[TBL] [Abstract][Full Text] [Related]
7. Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells.
Dowling RJ; Zakikhani M; Fantus IG; Pollak M; Sonenberg N
Cancer Res; 2007 Nov; 67(22):10804-12. PubMed ID: 18006825
[TBL] [Abstract][Full Text] [Related]
8. The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin.
Shaw RJ; Lamia KA; Vasquez D; Koo SH; Bardeesy N; Depinho RA; Montminy M; Cantley LC
Science; 2005 Dec; 310(5754):1642-6. PubMed ID: 16308421
[TBL] [Abstract][Full Text] [Related]
9. Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state.
Foretz M; Hébrard S; Leclerc J; Zarrinpashneh E; Soty M; Mithieux G; Sakamoto K; Andreelli F; Viollet B
J Clin Invest; 2010 Jul; 120(7):2355-69. PubMed ID: 20577053
[TBL] [Abstract][Full Text] [Related]
10. Sodium arsenite induces orphan nuclear receptor SHP gene expression via AMP-activated protein kinase to inhibit gluconeogenic enzyme gene expression.
Chanda D; Kim SJ; Lee IK; Shong M; Choi HS
Am J Physiol Endocrinol Metab; 2008 Aug; 295(2):E368-79. PubMed ID: 18505831
[TBL] [Abstract][Full Text] [Related]
11. Loss of cytoplasmic retention ability of mutant LKB1 found in Peutz-Jeghers syndrome patients.
Nezu J; Oku A; Shimane M
Biochem Biophys Res Commun; 1999 Aug; 261(3):750-5. PubMed ID: 10441497
[TBL] [Abstract][Full Text] [Related]
12. Stability of the Peutz-Jeghers syndrome kinase LKB1 requires its binding to the molecular chaperones Hsp90/Cdc37.
Nony P; Gaude H; Rossel M; Fournier L; Rouault JP; Billaud M
Oncogene; 2003 Dec; 22(57):9165-75. PubMed ID: 14668798
[TBL] [Abstract][Full Text] [Related]
13. LKB1 mutation in large cell carcinoma of the lung.
Zhong D; Guo L; de Aguirre I; Liu X; Lamb N; Sun SY; Gal AA; Vertino PM; Zhou W
Lung Cancer; 2006 Sep; 53(3):285-94. PubMed ID: 16822578
[TBL] [Abstract][Full Text] [Related]
14. The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level.
Ben Sahra I; Laurent K; Loubat A; Giorgetti-Peraldi S; Colosetti P; Auberger P; Tanti JF; Le Marchand-Brustel Y; Bost F
Oncogene; 2008 Jun; 27(25):3576-86. PubMed ID: 18212742
[TBL] [Abstract][Full Text] [Related]
15. Functional analysis of LKB1/STK11 mutants and two aberrant isoforms found in Peutz-Jeghers Syndrome patients.
Boudeau J; Kieloch A; Alessi DR; Stella A; Guanti G; Resta N
Hum Mutat; 2003 Feb; 21(2):172. PubMed ID: 12552571
[TBL] [Abstract][Full Text] [Related]
16. LKB1; linking cell structure and tumor suppression.
Hezel AF; Bardeesy N
Oncogene; 2008 Nov; 27(55):6908-19. PubMed ID: 19029933
[TBL] [Abstract][Full Text] [Related]
17. Chutes and Ladders: the search for protein kinases that act on AMPK.
Witters LA; Kemp BE; Means AR
Trends Biochem Sci; 2006 Jan; 31(1):13-6. PubMed ID: 16356723
[TBL] [Abstract][Full Text] [Related]
18. No evidence of Peutz-Jeghers syndrome gene LKB1 involvement in left-sided colorectal carcinomas.
Launonen V; Avizienyte E; Loukola A; Laiho P; Salovaara R; Järvinen H; Mecklin JP; Oku A; Shimane M; Kim HC; Kim JC; Nezu J; Aaltonen LA
Cancer Res; 2000 Feb; 60(3):546-8. PubMed ID: 10676634
[TBL] [Abstract][Full Text] [Related]
19. Medicine. Cancer-suppressing enzyme adds a link to type 2 diabetes.
Marx J
Science; 2005 Nov; 310(5752):1259. PubMed ID: 16311305
[No Abstract] [Full Text] [Related]
20. Isodihydrocapsiate stimulates plasma glucose uptake by activation of AMP-activated protein kinase.
Hwang SL; Yang BK; Lee JY; Kim JH; Kim BD; Suh KH; Kim DY; Kim MS; Song H; Park BS; Huh TL
Biochem Biophys Res Commun; 2008 Jun; 371(2):289-93. PubMed ID: 18435912
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
