BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

122 related articles for article (PubMed ID: 16530458)

  • 1. A single point mutation in the low-density lipoprotein receptor switches the degradation of its mature protein from the proteasome to the lysosome.
    Martín de Llano JJ; Fuertes G; Andreu EJ; Puig O; Chaves FJ; Soutar AK; Armengod ME; Knecht E
    Int J Biochem Cell Biol; 2006; 38(8):1340-51. PubMed ID: 16530458
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Degradation of the LDL receptor class 2 mutants is mediated by a proteasome-dependent pathway.
    Li Y; Lu W; Schwartz AL; Bu G
    J Lipid Res; 2004 Jun; 45(6):1084-91. PubMed ID: 14993243
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effects of pH and low density lipoprotein (LDL) on PCSK9-dependent LDL receptor regulation.
    Fisher TS; Lo Surdo P; Pandit S; Mattu M; Santoro JC; Wisniewski D; Cummings RT; Calzetta A; Cubbon RM; Fischer PA; Tarachandani A; De Francesco R; Wright SD; Sparrow CP; Carfi A; Sitlani A
    J Biol Chem; 2007 Jul; 282(28):20502-12. PubMed ID: 17493938
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Toxoplasma gondii exploits host low-density lipoprotein receptor-mediated endocytosis for cholesterol acquisition.
    Coppens I; Sinai AP; Joiner KA
    J Cell Biol; 2000 Apr; 149(1):167-80. PubMed ID: 10747095
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and properties of the very-low-density-lipoprotein receptor and a comparison with the low-density-lipoprotein receptor.
    Patel DD; Forder RA; Soutar AK; Knight BL
    Biochem J; 1997 Jun; 324 ( Pt 2)(Pt 2):371-7. PubMed ID: 9182693
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Proteasome regulates the delivery of LDL receptor-related protein into the degradation pathway.
    Melman L; Geuze HJ; Li Y; McCormick LM; Van Kerkhof P; Strous GJ; Schwartz AL; Bu G
    Mol Biol Cell; 2002 Sep; 13(9):3325-35. PubMed ID: 12221136
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Overexpression of PCSK9 accelerates the degradation of the LDLR in a post-endoplasmic reticulum compartment.
    Maxwell KN; Fisher EA; Breslow JL
    Proc Natl Acad Sci U S A; 2005 Feb; 102(6):2069-74. PubMed ID: 15677715
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A chimeric LDL receptor containing the cytoplasmic domain of the transferrin receptor is degraded by PCSK9.
    Holla ØL; Strøm TB; Cameron J; Berge KE; Leren TP
    Mol Genet Metab; 2010 Feb; 99(2):149-56. PubMed ID: 19828345
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The cytoplasmic domain is not involved in directing Class 5 mutant LDL receptors to lysosomal degradation.
    Strøm TB; Tveten K; Holla ØL; Cameron J; Berge KE; Leren TP
    Biochem Biophys Res Commun; 2011 May; 408(4):642-6. PubMed ID: 21531209
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-function relationship of lipoprotein lipase-mediated enhancement of very low density lipoprotein binding and catabolism by the low density lipoprotein receptor. Functional importance of a properly folded surface loop covering the catalytic center.
    Salinelli S; Lo JY; Mims MP; Zsigmond E; Smith LC; Chan L
    J Biol Chem; 1996 Sep; 271(36):21906-13. PubMed ID: 8702993
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inducible nitric-oxide synthase is regulated by the proteasome degradation pathway.
    Musial A; Eissa NT
    J Biol Chem; 2001 Jun; 276(26):24268-73. PubMed ID: 11312270
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Proprotein Convertase Subtilisin/Kexin Type 9-resistant R410S Low Density Lipoprotein Receptor Mutation: A NOVEL MECHANISM CAUSING FAMILIAL HYPERCHOLESTEROLEMIA.
    Susan-Resiga D; Girard E; Kiss RS; Essalmani R; Hamelin J; Asselin MC; Awan Z; Butkinaree C; Fleury A; Soldera A; Dory YL; Baass A; Seidah NG
    J Biol Chem; 2017 Feb; 292(5):1573-1590. PubMed ID: 27998977
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Isolation of three classes of conditional lethal Chinese hamster ovary cell mutants with temperature-dependent defects in low density lipoprotein receptor stability and intracellular membrane transport.
    Hobbie L; Fisher AS; Lee S; Flint A; Krieger M
    J Biol Chem; 1994 Aug; 269(33):20958-70. PubMed ID: 8063714
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Stabilization of mutant 46-kDa mannose 6-phosphate receptors by proteasomal inhibitor lactacystin.
    Breuer P; Braulke T
    J Biol Chem; 1998 Dec; 273(50):33254-8. PubMed ID: 9837896
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Real-time imaging of sodium glucose transporter (SGLT1) trafficking and activity in single cells.
    Ghezzi C; Calmettes G; Morand P; Ribalet B; John S
    Physiol Rep; 2017 Feb; 5(3):. PubMed ID: 28193781
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Insect lipoprotein follows a transferrin-like recycling pathway that is mediated by the insect LDL receptor homologue.
    Van Hoof D; Rodenburg KW; Van der Horst DJ
    J Cell Sci; 2002 Nov; 115(Pt 21):4001-12. PubMed ID: 12356906
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The proprotein convertase PCSK9 induces the degradation of low density lipoprotein receptor (LDLR) and its closest family members VLDLR and ApoER2.
    Poirier S; Mayer G; Benjannet S; Bergeron E; Marcinkiewicz J; Nassoury N; Mayer H; Nimpf J; Prat A; Seidah NG
    J Biol Chem; 2008 Jan; 283(4):2363-72. PubMed ID: 18039658
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Low-density lipoprotein receptor point mutation results in expression of both active and inactive surface forms of the same mutant receptor.
    Fourie AM; Coetzee GA; Gevers W; van der Westhuyzen DR
    Biochemistry; 1992 Dec; 31(51):12754-9. PubMed ID: 1463746
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Replacement of cysteine at position 46 in the first cysteine-rich repeat of the LDL receptor impairs apolipoprotein recognition.
    Benito-Vicente A; Uribe KB; Siddiqi H; Jebari S; Galicia-Garcia U; Larrea-Sebal A; Cenarro A; Stef M; Ostolaza H; Civeira F; Palacios L; Martin C
    PLoS One; 2018; 13(10):e0204771. PubMed ID: 30332439
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Annexin VI stimulates endocytosis and is involved in the trafficking of low density lipoprotein to the prelysosomal compartment.
    Grewal T; Heeren J; Mewawala D; Schnitgerhans T; Wendt D; Salomon G; Enrich C; Beisiegel U; Jäckle S
    J Biol Chem; 2000 Oct; 275(43):33806-13. PubMed ID: 10940299
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.