293 related articles for article (PubMed ID: 1654286)
1. The reductive metabolism of diaziquone (AZQ) in the S9 fraction of MCF-7 cells: free radical formation and NAD(P)H: quinone-acceptor oxidoreductase (DT-diaphorase) activity.
Fisher GR; Gutierrez PL
Free Radic Biol Med; 1991; 10(6):359-70. PubMed ID: 1654286
[TBL] [Abstract][Full Text] [Related]
2. Metabolism of diaziquone by NAD(P)H:(quinone acceptor) oxidoreductase (DT-diaphorase): role in diaziquone-induced DNA damage and cytotoxicity in human colon carcinoma cells.
Siegel D; Gibson NW; Preusch PC; Ross D
Cancer Res; 1990 Nov; 50(22):7293-300. PubMed ID: 2121335
[TBL] [Abstract][Full Text] [Related]
3. Reductive metabolism of diaziquone (AZQ) in the S9 fraction of MCF-7 cells. II. Enhancement of the alkylating activity of AZQ by NAD(P)H: quinone-acceptor oxidoreductase (DT-diaphorase).
Fisher GR; Donis J; Gutierrez PL
Biochem Pharmacol; 1992 Oct; 44(8):1625-35. PubMed ID: 1301071
[TBL] [Abstract][Full Text] [Related]
4. Free radical formation and DNA strand breakage during metabolism of diaziquone by NAD(P)H quinone-acceptor oxidoreductase (DT-diaphorase) and NADPH cytochrome c reductase.
Fisher GR; Gutierrez PL
Free Radic Biol Med; 1991; 11(6):597-607. PubMed ID: 1663902
[TBL] [Abstract][Full Text] [Related]
5. Thiol oxidation coupled to DT-diaphorase-catalysed reduction of diaziquone. Reductive and oxidative pathways of diaziquone semiquinone modulated by glutathione and superoxide dismutase.
Ordoñez ID; Cadenas E
Biochem J; 1992 Sep; 286 ( Pt 2)(Pt 2):481-90. PubMed ID: 1530580
[TBL] [Abstract][Full Text] [Related]
6. The role of NAD(P)H:quinone oxidoreductase in quinone-mediated p21 induction in human colon carcinoma cells.
Qiu XB; Cadenas E
Arch Biochem Biophys; 1997 Oct; 346(2):241-51. PubMed ID: 9343371
[TBL] [Abstract][Full Text] [Related]
7. A comparison of free radical formation by quinone antitumour agents in MCF-7 cells and the role of NAD(P)H (quinone-acceptor) oxidoreductase (DT-diaphorase).
Fisher GR; Patterson LH; Gutierrez PL
Chem Biol Interact; 1993 Sep; 88(2-3):137-53. PubMed ID: 8403076
[TBL] [Abstract][Full Text] [Related]
8. The influence of diaziquone free radicals on the in vitro activity of diaziquone.
Nguyen B; Biswal S; Gutierrez PL
Xenobiotica; 1988 May; 18(5):593-602. PubMed ID: 2840783
[TBL] [Abstract][Full Text] [Related]
9. Activation and deactivation of quinones catalyzed by DT-diaphorase. Evidence for bioreductive activation of diaziquone (AZQ) in human tumor cells and detoxification of benzene metabolites in bone marrow stroma.
Ross D; Siegel D; Gibson NW; Pacheco D; Thomas DJ; Reasor M; Wierda D
Free Radic Res Commun; 1990; 8(4-6):373-81. PubMed ID: 2113030
[TBL] [Abstract][Full Text] [Related]
10. Induction of p21 mediated by reactive oxygen species formed during the metabolism of aziridinylbenzoquinones by HCT116 cells.
Qiu X; Forman HJ; Schönthal AH; Cadenas E
J Biol Chem; 1996 Dec; 271(50):31915-21. PubMed ID: 8943236
[TBL] [Abstract][Full Text] [Related]
11. The role of NAD(P)H: quinone reductase (EC 1.6.99.2, DT-diaphorase) in the reductive bioactivation of the novel indoloquinone antitumor agent EO9.
Walton MI; Smith PJ; Workman P
Cancer Commun; 1991 Jul; 3(7):199-206. PubMed ID: 1714284
[TBL] [Abstract][Full Text] [Related]
12. Relationship between DT-diaphorase-mediated metabolism of a series of aziridinylbenzoquinones and DNA damage and cytotoxicity.
Gibson NW; Hartley JA; Butler J; Siegel D; Ross D
Mol Pharmacol; 1992 Sep; 42(3):531-6. PubMed ID: 1406604
[TBL] [Abstract][Full Text] [Related]
13. The effect of functional groups on reduction and activation of quinone bioreductive agents by DT-diaphorase.
Fourie J; Oleschuk CJ; Guziec F; Guziec L; Fiterman DJ; Monterrosa C; Begleiter A
Cancer Chemother Pharmacol; 2002 Feb; 49(2):101-10. PubMed ID: 11862423
[TBL] [Abstract][Full Text] [Related]
14. Structure-activity relationships for DT-diaphorase reduction of hypoxic cell directed agents: indoloquinones and diaziridinyl benzoquinones.
Bailey SM; Suggett N; Walton MI; Workman P
Int J Radiat Oncol Biol Phys; 1992; 22(4):649-53. PubMed ID: 1544832
[TBL] [Abstract][Full Text] [Related]
15. Reductive activation of diaziquone and possible involvement of free radicals and the hydroquinone dianion.
Gutierrez PL; Biswal S; Nardino R; Biswal N
Cancer Res; 1986 Nov; 46(11):5779-85. PubMed ID: 3019536
[TBL] [Abstract][Full Text] [Related]
16. Trace detection of hydroxyl radicals during the redox cycling of low concentrations of diaziquone: a new approach.
Li B; Blough NV; Gutierrez PL
Free Radic Biol Med; 2000 Sep; 29(6):548-56. PubMed ID: 11025198
[TBL] [Abstract][Full Text] [Related]
17. Diaziquone-glutathione conjugates: characterization and mechanisms of formation.
Gutierrez PL; Siva S
Chem Res Toxicol; 1995; 8(3):455-64. PubMed ID: 7578933
[TBL] [Abstract][Full Text] [Related]
18. Catalytic properties of NAD(P)H:quinone oxidoreductase-2 (NQO2), a dihydronicotinamide riboside dependent oxidoreductase.
Wu K; Knox R; Sun XZ; Joseph P; Jaiswal AK; Zhang D; Deng PS; Chen S
Arch Biochem Biophys; 1997 Nov; 347(2):221-8. PubMed ID: 9367528
[TBL] [Abstract][Full Text] [Related]
19. DT-diaphorase. Redox potential, steady-state, and rapid reaction studies.
Tedeschi G; Chen S; Massey V
J Biol Chem; 1995 Jan; 270(3):1198-204. PubMed ID: 7836380
[TBL] [Abstract][Full Text] [Related]
20. A note on the inhibition of DT-diaphorase by dicoumarol.
Preusch PC; Siegel D; Gibson NW; Ross D
Free Radic Biol Med; 1991; 11(1):77-80. PubMed ID: 1718826
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
