BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

855 related articles for article (PubMed ID: 16543246)

  • 21. R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling.
    Carmon KS; Gong X; Lin Q; Thomas A; Liu Q
    Proc Natl Acad Sci U S A; 2011 Jul; 108(28):11452-7. PubMed ID: 21693646
    [TBL] [Abstract][Full Text] [Related]  

  • 22. ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner.
    Hao HX; Xie Y; Zhang Y; Charlat O; Oster E; Avello M; Lei H; Mickanin C; Liu D; Ruffner H; Mao X; Ma Q; Zamponi R; Bouwmeester T; Finan PM; Kirschner MW; Porter JA; Serluca FC; Cong F
    Nature; 2012 Apr; 485(7397):195-200. PubMed ID: 22575959
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The low-density lipoprotein receptor-related protein 10 is a negative regulator of the canonical Wnt/beta-catenin signaling pathway.
    Jeong YH; Sekiya M; Hirata M; Ye M; Yamagishi A; Lee SM; Kang MJ; Hosoda A; Fukumura T; Kim DH; Saeki S
    Biochem Biophys Res Commun; 2010 Feb; 392(4):495-9. PubMed ID: 20093106
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Analysis of endogenous LRP6 function reveals a novel feedback mechanism by which Wnt negatively regulates its receptor.
    Khan Z; Vijayakumar S; de la Torre TV; Rotolo S; Bafico A
    Mol Cell Biol; 2007 Oct; 27(20):7291-301. PubMed ID: 17698587
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Cripto-1 enhances the canonical Wnt/β-catenin signaling pathway by binding to LRP5 and LRP6 co-receptors.
    Nagaoka T; Karasawa H; Turbyville T; Rangel MC; Castro NP; Gonzales M; Baker A; Seno M; Lockett S; Greer YE; Rubin JS; Salomon DS; Bianco C
    Cell Signal; 2013 Jan; 25(1):178-89. PubMed ID: 23022962
    [TBL] [Abstract][Full Text] [Related]  

  • 26. LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-catenin.
    Cselenyi CS; Jernigan KK; Tahinci E; Thorne CA; Lee LA; Lee E
    Proc Natl Acad Sci U S A; 2008 Jun; 105(23):8032-7. PubMed ID: 18509060
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context.
    Mikels AJ; Nusse R
    PLoS Biol; 2006 Apr; 4(4):e115. PubMed ID: 16602827
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Low-density lipoprotein receptor-related protein 6 is a novel coreceptor of protease-activated receptor-2 in the dynamics of cancer-associated β-catenin stabilization.
    Nag JK; Kancharla A; Maoz M; Turm H; Agranovich D; Gupta CL; Uziely B; Bar-Shavit R
    Oncotarget; 2017 Jun; 8(24):38650-38667. PubMed ID: 28418856
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling.
    Janda CY; Dang LT; You C; Chang J; de Lau W; Zhong ZA; Yan KS; Marecic O; Siepe D; Li X; Moody JD; Williams BO; Clevers H; Piehler J; Baker D; Kuo CJ; Garcia KC
    Nature; 2017 May; 545(7653):234-237. PubMed ID: 28467818
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Differential activities and mechanisms of the four R-spondins in potentiating Wnt/β-catenin signaling.
    Park S; Cui J; Yu W; Wu L; Carmon KS; Liu QJ
    J Biol Chem; 2018 Jun; 293(25):9759-9769. PubMed ID: 29752411
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Truncated mutants of the putative Wnt receptor LRP6/Arrow can stabilize beta-catenin independently of Frizzled proteins.
    Brennan K; Gonzalez-Sancho JM; Castelo-Soccio LA; Howe LR; Brown AM
    Oncogene; 2004 Jun; 23(28):4873-84. PubMed ID: 15064719
    [TBL] [Abstract][Full Text] [Related]  

  • 32. A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation.
    Zeng X; Tamai K; Doble B; Li S; Huang H; Habas R; Okamura H; Woodgett J; He X
    Nature; 2005 Dec; 438(7069):873-7. PubMed ID: 16341017
    [TBL] [Abstract][Full Text] [Related]  

  • 33. A novel set of Wnt-Frizzled fusion proteins identifies receptor components that activate beta -catenin-dependent signaling.
    Holmen SL; Salic A; Zylstra CR; Kirschner MW; Williams BO
    J Biol Chem; 2002 Sep; 277(38):34727-35. PubMed ID: 12121999
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Wnt/beta-catenin signaling: components, mechanisms, and diseases.
    MacDonald BT; Tamai K; He X
    Dev Cell; 2009 Jul; 17(1):9-26. PubMed ID: 19619488
    [TBL] [Abstract][Full Text] [Related]  

  • 35. LRP6 dimerization through its LDLR domain is required for robust canonical Wnt pathway activation.
    Chen J; Yan H; Ren DN; Yin Y; Li Z; He Q; Wo D; Ho MS; Chen Y; Liu Z; Yang J; Liu S; Zhu W
    Cell Signal; 2014 May; 26(5):1068-74. PubMed ID: 24412751
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Context-dependent activation or inhibition of Wnt-beta-catenin signaling by Kremen.
    Cselenyi CS; Lee E
    Sci Signal; 2008 Feb; 1(8):pe10. PubMed ID: 18314504
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Stably overexpressed human Frizzled-2 signals through the beta-catenin pathway and does not activate Ca2+-mobilization in Human Embryonic Kidney 293 cells.
    Verkaar F; van Rosmalen JW; Smits JF; Blankesteijn WM; Zaman GJ
    Cell Signal; 2009 Jan; 21(1):22-33. PubMed ID: 18929644
    [TBL] [Abstract][Full Text] [Related]  

  • 38. LDL-receptor-related protein 6 is a receptor for Dickkopf proteins.
    Mao B; Wu W; Li Y; Hoppe D; Stannek P; Glinka A; Niehrs C
    Nature; 2001 May; 411(6835):321-5. PubMed ID: 11357136
    [TBL] [Abstract][Full Text] [Related]  

  • 39. WNT-3A-induced β-catenin signaling does not require signaling through heterotrimeric G proteins.
    Bowin CF; Inoue A; Schulte G
    J Biol Chem; 2019 Aug; 294(31):11677-11684. PubMed ID: 31235524
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Regulated proteolytic processing of LRP6 results in release of its intracellular domain.
    Mi K; Johnson GV
    J Neurochem; 2007 Apr; 101(2):517-29. PubMed ID: 17326769
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 43.