BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

204 related articles for article (PubMed ID: 16546970)

  • 1. Radiosensitization by the poly(ADP-ribose) polymerase inhibitor 4-amino-1,8-naphthalimide is specific of the S phase of the cell cycle and involves arrest of DNA synthesis.
    Noël G; Godon C; Fernet M; Giocanti N; Mégnin-Chanet F; Favaudon V
    Mol Cancer Ther; 2006 Mar; 5(3):564-74. PubMed ID: 16546970
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 4-Amino-1,8-naphthalimide: a novel inhibitor of poly(ADP-ribose) polymerase and radiation sensitizer.
    Schlicker A; Peschke P; Bürkle A; Hahn EW; Kim JH
    Int J Radiat Biol; 1999 Jan; 75(1):91-100. PubMed ID: 9972795
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of poly (ADP-ribose) polymerase activates ATM which is required for subsequent homologous recombination repair.
    Bryant HE; Helleday T
    Nucleic Acids Res; 2006; 34(6):1685-91. PubMed ID: 16556909
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PARP inhibition versus PARP-1 silencing: different outcomes in terms of single-strand break repair and radiation susceptibility.
    Godon C; Cordelières FP; Biard D; Giocanti N; Mégnin-Chanet F; Hall J; Favaudon V
    Nucleic Acids Res; 2008 Aug; 36(13):4454-64. PubMed ID: 18603595
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sensitization to radiation and alkylating agents by inhibitors of poly(ADP-ribose) polymerase is enhanced in cells deficient in DNA double-strand break repair.
    Löser DA; Shibata A; Shibata AK; Woodbine LJ; Jeggo PA; Chalmers AJ
    Mol Cancer Ther; 2010 Jun; 9(6):1775-87. PubMed ID: 20530711
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Alkylation DNA damage in combination with PARP inhibition results in formation of S-phase-dependent double-strand breaks.
    Heacock ML; Stefanick DF; Horton JK; Wilson SH
    DNA Repair (Amst); 2010 Aug; 9(8):929-36. PubMed ID: 20573551
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PARP inhibition sensitizes p53-deficient breast cancer cells to doxorubicin-induced apoptosis.
    Muñoz-Gámez JA; Martín-Oliva D; Aguilar-Quesada R; Cañuelo A; Nuñez MI; Valenzuela MT; Ruiz de Almodóvar JM; De Murcia G; Oliver FJ
    Biochem J; 2005 Feb; 386(Pt 1):119-25. PubMed ID: 15456408
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Poly(ADP-ribose) polymerase activity prevents signaling pathways for cell cycle arrest after DNA methylating agent exposure.
    Horton JK; Stefanick DF; Naron JM; Kedar PS; Wilson SH
    J Biol Chem; 2005 Apr; 280(16):15773-85. PubMed ID: 15701627
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Requirement for NBS1 in the S phase checkpoint response to DNA methylation combined with PARP inhibition.
    Horton JK; Stefanick DF; Zeng JY; Carrozza MJ; Wilson SH
    DNA Repair (Amst); 2011 Feb; 10(2):225-34. PubMed ID: 21130714
    [TBL] [Abstract][Full Text] [Related]  

  • 10. PARP-1, PARP-2, and the cellular response to low doses of ionizing radiation.
    Chalmers A; Johnston P; Woodcock M; Joiner M; Marples B
    Int J Radiat Oncol Biol Phys; 2004 Feb; 58(2):410-9. PubMed ID: 14751510
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Induction of apoptosis by the inhibitors of poly(ADP-ribose)polymerase in HeLa cells.
    Ghosh U; Bhattacharyya NP
    Mol Cell Biochem; 2009 Jan; 320(1-2):15-23. PubMed ID: 18695944
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Poly(ADP-ribose) polymerase (PARP-1) is not involved in DNA double-strand break recovery.
    Noël G; Giocanti N; Fernet M; Mégnin-Chanet F; Favaudon V
    BMC Cell Biol; 2003 Jul; 4():7. PubMed ID: 12866953
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Radiosensitization and DNA repair inhibition by the combined use of novel inhibitors of DNA-dependent protein kinase and poly(ADP-ribose) polymerase-1.
    Veuger SJ; Curtin NJ; Richardson CJ; Smith GC; Durkacz BW
    Cancer Res; 2003 Sep; 63(18):6008-15. PubMed ID: 14522929
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Preventing oxidation of cellular XRCC1 affects PARP-mediated DNA damage responses.
    Horton JK; Stefanick DF; Gassman NR; Williams JG; Gabel SA; Cuneo MJ; Prasad R; Kedar PS; Derose EF; Hou EW; London RE; Wilson SH
    DNA Repair (Amst); 2013 Sep; 12(9):774-85. PubMed ID: 23871146
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Radiosensitization effect of poly(ADP-ribose) polymerase inhibition in cells exposed to low and high liner energy transfer radiation.
    Hirai T; Shirai H; Fujimori H; Okayasu R; Sasai K; Masutani M
    Cancer Sci; 2012 Jun; 103(6):1045-50. PubMed ID: 22404155
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A stronger DNA damage-induced G2 checkpoint due to over-activated CHK1 in the absence of PARP-1.
    Lu HR; Wang X; Wang Y
    Cell Cycle; 2006 Oct; 5(20):2364-70. PubMed ID: 17102615
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Replication-dependent radiosensitization of human glioma cells by inhibition of poly(ADP-Ribose) polymerase: mechanisms and therapeutic potential.
    Dungey FA; Löser DA; Chalmers AJ
    Int J Radiat Oncol Biol Phys; 2008 Nov; 72(4):1188-97. PubMed ID: 18954712
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Poly(ADP-ribose) polymerase inhibition reduces tumor necrosis factor-induced inflammatory response in rheumatoid synovial fibroblasts.
    García S; Bodaño A; Pablos JL; Gómez-Reino JJ; Conde C
    Ann Rheum Dis; 2008 May; 67(5):631-7. PubMed ID: 17890271
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ATR signaling mediates an S-phase checkpoint after inhibition of poly(ADP-ribose) polymerase activity.
    Horton JK; Stefanick DF; Kedar PS; Wilson SH
    DNA Repair (Amst); 2007 Jun; 6(6):742-50. PubMed ID: 17292679
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Predicting enhanced cell killing through PARP inhibition.
    Horton JK; Wilson SH
    Mol Cancer Res; 2013 Jan; 11(1):13-8. PubMed ID: 23193155
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.