233 related articles for article (PubMed ID: 16546987)
1. Semisynthetic homoharringtonine induces apoptosis via inhibition of protein synthesis and triggers rapid myeloid cell leukemia-1 down-regulation in myeloid leukemia cells.
Tang R; Faussat AM; Majdak P; Marzac C; Dubrulle S; Marjanovic Z; Legrand O; Marie JP
Mol Cancer Ther; 2006 Mar; 5(3):723-31. PubMed ID: 16546987
[TBL] [Abstract][Full Text] [Related]
2. Apoptosis of human leukemia HL-60 cells and murine leukemia WEHI-3 cells induced by berberine through the activation of caspase-3.
Lin CC; Kao ST; Chen GW; Ho HC; Chung JG
Anticancer Res; 2006; 26(1A):227-42. PubMed ID: 16475703
[TBL] [Abstract][Full Text] [Related]
3. Specific cleavage of Mcl-1 by caspase-3 in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in Jurkat leukemia T cells.
Weng C; Li Y; Xu D; Shi Y; Tang H
J Biol Chem; 2005 Mar; 280(11):10491-500. PubMed ID: 15637055
[TBL] [Abstract][Full Text] [Related]
4. Homoharringtonine reduced Mcl-1 expression and induced apoptosis in chronic lymphocytic leukemia.
Chen R; Guo L; Chen Y; Jiang Y; Wierda WG; Plunkett W
Blood; 2011 Jan; 117(1):156-64. PubMed ID: 20971952
[TBL] [Abstract][Full Text] [Related]
5. Apoptotic response to homoharringtonine in human wt p53 leukemic cells is independent of reactive oxygen species generation and implicates Bax translocation, mitochondrial cytochrome c release and caspase activation.
Cai Z; Lin M; Wuchter C; Ruppert V; Dörken B; Ludwig WD; Karawajew L
Leukemia; 2001 Apr; 15(4):567-74. PubMed ID: 11368358
[TBL] [Abstract][Full Text] [Related]
6. Downregulation of the antiapoptotic MCL-1 protein and apoptosis in MA-11 breast cancer cells induced by an anti-epidermal growth factor receptor-Pseudomonas exotoxin a immunotoxin.
Andersson Y; Juell S; Fodstad Ø
Int J Cancer; 2004 Nov; 112(3):475-83. PubMed ID: 15382075
[TBL] [Abstract][Full Text] [Related]
7. MPT0B169, a novel tubulin inhibitor, induces apoptosis in taxol-resistant acute myeloid leukemia cells through mitochondrial dysfunction and Mcl-1 downregulation.
Wang CC; Liu HE; Lee YL; Huang YW; Chen YJ; Liou JP; Huang HM
Tumour Biol; 2016 May; 37(5):6065-72. PubMed ID: 26608370
[TBL] [Abstract][Full Text] [Related]
8. Apoptosis induced by the kinase inhibitor BAY 43-9006 in human leukemia cells involves down-regulation of Mcl-1 through inhibition of translation.
Rahmani M; Davis EM; Bauer C; Dent P; Grant S
J Biol Chem; 2005 Oct; 280(42):35217-27. PubMed ID: 16109713
[TBL] [Abstract][Full Text] [Related]
9. Mcl-1 depletion in apoptosis elicited by ionizing radiation in peritoneal resident macrophages of C3H mice.
Kubota Y; Kinoshita K; Suetomi K; Fujimori A; Takahashi S
J Immunol; 2007 Mar; 178(5):2923-31. PubMed ID: 17312137
[TBL] [Abstract][Full Text] [Related]
10. Potentiation of the lethality of the histone deacetylase inhibitor LAQ824 by the cyclin-dependent kinase inhibitor roscovitine in human leukemia cells.
Rosato RR; Almenara JA; Maggio SC; Atadja P; Craig R; Vrana J; Dent P; Grant S
Mol Cancer Ther; 2005 Nov; 4(11):1772-85. PubMed ID: 16275999
[TBL] [Abstract][Full Text] [Related]
11. The histone deacetylase inhibitor suberic bishydroxamate regulates the expression of multiple apoptotic mediators and induces mitochondria-dependent apoptosis of melanoma cells.
Zhang XD; Gillespie SK; Borrow JM; Hersey P
Mol Cancer Ther; 2004 Apr; 3(4):425-35. PubMed ID: 15078986
[TBL] [Abstract][Full Text] [Related]
12. Mechanism and functional role of XIAP and Mcl-1 down-regulation in flavopiridol/vorinostat antileukemic interactions.
Rosato RR; Almenara JA; Kolla SS; Maggio SC; Coe S; Giménez MS; Dent P; Grant S
Mol Cancer Ther; 2007 Feb; 6(2):692-702. PubMed ID: 17308065
[TBL] [Abstract][Full Text] [Related]
13. The multikinase inhibitor sorafenib potentiates TRAIL lethality in human leukemia cells in association with Mcl-1 and cFLIPL down-regulation.
Rosato RR; Almenara JA; Coe S; Grant S
Cancer Res; 2007 Oct; 67(19):9490-500. PubMed ID: 17909059
[TBL] [Abstract][Full Text] [Related]
14. The pyridone-annelated isoindigo (5'-Cl) induces apoptosis, dysregulation of mitochondria and formation of ROS in leukemic HL-60 cells.
Saleh AM; Aljada A; El-Abadelah MM; Sabri SS; Zahra JA; Nasr A; Aziz MA
Cell Physiol Biochem; 2015; 35(5):1958-74. PubMed ID: 25871324
[TBL] [Abstract][Full Text] [Related]
15. Homoharringtonine mediates myeloid cell apoptosis via upregulation of pro-apoptotic bax and inducing caspase-3-mediated cleavage of poly(ADP-ribose) polymerase (PARP).
Yinjun L; Jie J; Weilai X; Xiangming T
Am J Hematol; 2004 Jul; 76(3):199-204. PubMed ID: 15224352
[TBL] [Abstract][Full Text] [Related]
16. Caspase-9-induced mitochondrial disruption through cleavage of anti-apoptotic BCL-2 family members.
Chen M; Guerrero AD; Huang L; Shabier Z; Pan M; Tan TH; Wang J
J Biol Chem; 2007 Nov; 282(46):33888-33895. PubMed ID: 17893147
[TBL] [Abstract][Full Text] [Related]
17. Farnesyltransferase inhibitor BMS-214662 induces apoptosis in myeloma cells through PUMA up-regulation, Bax and Bak activation, and Mcl-1 elimination.
Gómez-Benito M; Marzo I; Anel A; Naval J
Mol Pharmacol; 2005 Jun; 67(6):1991-8. PubMed ID: 15738311
[TBL] [Abstract][Full Text] [Related]
18. Leptomycin B-induced apoptosis is mediated through caspase activation and down-regulation of Mcl-1 and XIAP expression, but not through the generation of ROS in U937 leukemia cells.
Jang BC; Paik JH; Jeong HY; Oh HJ; Park JW; Kwon TK; Song DK; Park JG; Kim SP; Bae JH; Mun KC; Suh MH; Yoshida M; Suh SI
Biochem Pharmacol; 2004 Jul; 68(2):263-74. PubMed ID: 15193998
[TBL] [Abstract][Full Text] [Related]
19. Curcumin induces mitochondria pathway mediated cell apoptosis in A549 lung adenocarcinoma cells.
Chen QY; Lu GH; Wu YQ; Zheng Y; Xu K; Wu LJ; Jiang ZY; Feng R; Zhou JY
Oncol Rep; 2010 May; 23(5):1285-92. PubMed ID: 20372842
[TBL] [Abstract][Full Text] [Related]
20. Induction of apoptosis by apicidin, a histone deacetylase inhibitor, via the activation of mitochondria-dependent caspase cascades in human Bcr-Abl-positive leukemia cells.
Cheong JW; Chong SY; Kim JY; Eom JI; Jeung HK; Maeng HY; Lee ST; Min YH
Clin Cancer Res; 2003 Oct; 9(13):5018-27. PubMed ID: 14581377
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
