These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

160 related articles for article (PubMed ID: 16551273)

  • 21. Mg2+ -dependent ATP occlusion at the first nucleotide-binding domain (NBD1) of CFTR does not require the second (NBD2).
    Aleksandrov L; Aleksandrov A; Riordan JR
    Biochem J; 2008 Nov; 416(1):129-36. PubMed ID: 18605986
    [TBL] [Abstract][Full Text] [Related]  

  • 22. ATP binding, not hydrolysis, at the first nucleotide-binding domain of multidrug resistance-associated protein MRP1 enhances ADP.Vi trapping at the second domain.
    Hou YX; Riordan JR; Chang XB
    J Biol Chem; 2003 Feb; 278(6):3599-605. PubMed ID: 12458196
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The two ATP binding sites of cystic fibrosis transmembrane conductance regulator (CFTR) play distinct roles in gating kinetics and energetics.
    Zhou Z; Wang X; Liu HY; Zou X; Li M; Hwang TC
    J Gen Physiol; 2006 Oct; 128(4):413-22. PubMed ID: 16966475
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Nucleotide triphosphatase activity of the N-terminal nucleotide-binding domains of the multidrug resistance proteins P-glycoprotein and MRP1.
    Wilkes DM; Wang C; Aristimuño PC; Castro AF; Altenberg GA
    Biochem Biophys Res Commun; 2002 Aug; 296(2):388-94. PubMed ID: 12163030
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Mutations of the Walker B motif in the first nucleotide binding domain of multidrug resistance protein MRP1 prevent conformational maturation.
    Cui L; Hou YX; Riordan JR; Chang XB
    Arch Biochem Biophys; 2001 Aug; 392(1):153-61. PubMed ID: 11469806
    [TBL] [Abstract][Full Text] [Related]  

  • 26. The hydroxyl group of S685 in Walker A motif and the carboxyl group of D792 in Walker B motif of NBD1 play a crucial role for multidrug resistance protein folding and function.
    Yang R; Scavetta R; Chang XB
    Biochim Biophys Acta; 2008 Feb; 1778(2):454-65. PubMed ID: 18088596
    [TBL] [Abstract][Full Text] [Related]  

  • 27. S-decyl-glutathione nonspecifically stimulates the ATPase activity of the nucleotide-binding domains of the human multidrug resistance-associated protein, MRP1 (ABCC1).
    Cool RH; Veenstra MK; van Klompenburg W; Heyne RI; Müller M; de Vries EG; van Veen HW; Konings WN
    Eur J Biochem; 2002 Jul; 269(14):3470-8. PubMed ID: 12135486
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Intermediate structural states involved in MRP1-mediated drug transport. Role of glutathione.
    Manciu L; Chang XB; Buyse F; Hou YX; Gustot A; Riordan JR; Ruysschaert JM
    J Biol Chem; 2003 Jan; 278(5):3347-56. PubMed ID: 12424247
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Protein kinase A regulates ATP hydrolysis and dimerization by a CFTR (cystic fibrosis transmembrane conductance regulator) domain.
    Howell LD; Borchardt R; Kole J; Kaz AM; Randak C; Cohn JA
    Biochem J; 2004 Feb; 378(Pt 1):151-9. PubMed ID: 14602047
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Analysis of catalytic carboxylate mutants E552Q and E1197Q suggests asymmetric ATP hydrolysis by the two nucleotide-binding domains of P-glycoprotein.
    Carrier I; Julien M; Gros P
    Biochemistry; 2003 Nov; 42(44):12875-85. PubMed ID: 14596601
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The Walker B motif of the second nucleotide-binding domain (NBD2) of CFTR plays a key role in ATPase activity by the NBD1-NBD2 heterodimer.
    Stratford FL; Ramjeesingh M; Cheung JC; Huan LJ; Bear CE
    Biochem J; 2007 Jan; 401(2):581-6. PubMed ID: 16989640
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Mutations of charged amino acids in or near the transmembrane helices of the second membrane spanning domain differentially affect the substrate specificity and transport activity of the multidrug resistance protein MRP1 (ABCC1).
    Haimeur A; Conseil G; Deeley RG; Cole SP
    Mol Pharmacol; 2004 Jun; 65(6):1375-85. PubMed ID: 15155831
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Differential functional rescue of Lys(513) and Lys(516) processing mutants of MRP1 (ABCC1) by chemical chaperones reveals different domain-domain interactions of the transporter.
    Iram SH; Cole SP
    Biochim Biophys Acta; 2014 Mar; 1838(3):756-65. PubMed ID: 24231430
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Prolonged nonhydrolytic interaction of nucleotide with CFTR's NH2-terminal nucleotide binding domain and its role in channel gating.
    Basso C; Vergani P; Nairn AC; Gadsby DC
    J Gen Physiol; 2003 Sep; 122(3):333-48. PubMed ID: 12939393
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Multiple roles of charged amino acids in cytoplasmic loop 7 for expression and function of the multidrug and organic anion transporter MRP1 (ABCC1).
    Conseil G; Rothnie AJ; Deeley RG; Cole SP
    Mol Pharmacol; 2009 Feb; 75(2):397-406. PubMed ID: 19015228
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Structure of the human multidrug resistance protein 1 nucleotide binding domain 1 bound to Mg2+/ATP reveals a non-productive catalytic site.
    Ramaen O; Leulliot N; Sizun C; Ulryck N; Pamlard O; Lallemand JY; Tilbeurgh Hv; Jacquet E
    J Mol Biol; 2006 Jun; 359(4):940-9. PubMed ID: 16697012
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Mutational analysis of a highly conserved proline residue in MRP1, MRP2, and MRP3 reveals a partially conserved function.
    Létourneau IJ; Slot AJ; Deeley RG; Cole SP
    Drug Metab Dispos; 2007 Aug; 35(8):1372-9. PubMed ID: 17494643
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Normal gating of CFTR requires ATP binding to both nucleotide-binding domains and hydrolysis at the second nucleotide-binding domain.
    Berger AL; Ikuma M; Welsh MJ
    Proc Natl Acad Sci U S A; 2005 Jan; 102(2):455-60. PubMed ID: 15623556
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Analysis of the AAA sensor-2 motif in the C-terminal ATPase domain of Hsp104 with a site-specific fluorescent probe of nucleotide binding.
    Hattendorf DA; Lindquist SL
    Proc Natl Acad Sci U S A; 2002 Mar; 99(5):2732-7. PubMed ID: 11867765
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Characterization of binding of leukotriene C4 by human multidrug resistance protein 1: evidence of differential interactions with NH2- and COOH-proximal halves of the protein.
    Qian YM; Qiu W; Gao M; Westlake CJ; Cole SP; Deeley RG
    J Biol Chem; 2001 Oct; 276(42):38636-44. PubMed ID: 11507101
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.