BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

170 related articles for article (PubMed ID: 1655249)

  • 1. Toxicity, mutagenicity, and mutational spectra of N-ethyl-N-nitrosourea in human cell lines with different DNA repair phenotypes.
    Bronstein SM; Cochrane JE; Craft TR; Swenberg JA; Skopek TR
    Cancer Res; 1991 Oct; 51(19):5188-97. PubMed ID: 1655249
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular characterization of mutations in the hprt gene of normal human skin keratinocytes treated with N-ethyl-N-nitrosourea: influence of O6-alkylguanine alkyltransferase.
    Tong HH; Park JH; Brady T; Weghorst CM; D'Ambrosio SM
    Environ Mol Mutagen; 1997; 29(2):168-79. PubMed ID: 9118969
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Marked differences in the role of O6-alkylguanine in hprt mutagenesis in T-lymphocytes of rats exposed in vivo to ethylmethanesulfonate, N-(2-hydroxyethyl)-N-nitrosourea, or N-ethyl-N-nitrosourea.
    Jansen JG; Vrieling H; van Teijlingen CM; Mohn GR; Tates AD; van Zeeland AA
    Cancer Res; 1995 May; 55(9):1875-82. PubMed ID: 7728755
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Strand- and sequence-specific attenuation of N-methyl-N'-nitro-N-nitrosoguanidine-induced G.C to A.T transitions by expression of human 6-methylguanine-DNA methyltransferase in Chinese hamster ovary cells.
    Yang JL; Hsieh FP; Lee PC; Tseng HJ
    Cancer Res; 1994 Jul; 54(14):3857-63. PubMed ID: 8033107
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Efficient repair of O6-ethylguanine, but not O4-ethylthymine or O2-ethylthymine, is dependent upon O6-alkylguanine-DNA alkyltransferase and nucleotide excision repair activities in human cells.
    Bronstein SM; Skopek TR; Swenberg JA
    Cancer Res; 1992 Apr; 52(7):2008-11. PubMed ID: 1551130
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular analysis of hprt gene mutations in skin fibroblasts of rats exposed in vivo to N-methyl-N-nitrosourea or N-ethyl-N-nitrosourea.
    Jansen JG; Mohn GR; Vrieling H; van Teijlingen CM; Lohman PH; van Zeeland AA
    Cancer Res; 1994 May; 54(9):2478-85. PubMed ID: 8162597
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Comparison of mutation spectra induced by N-ethyl-N-nitrosourea in the hprt gene of Mer+ and Mer- diploid human fibroblasts.
    Yang JL; Lee PC; Lin SR; Lin JG
    Carcinogenesis; 1994 May; 15(5):939-45. PubMed ID: 8200099
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutational spectra induced under distinct excision repair conditions by the 3 methylating agents N-methyl-N-nitrosourea, N-methyl-N'-nitro-N-nitrosoguanidine and N-nitrosodimethylamine in postmeiotic male germ cells of Drosophila.
    Nivard MJ; Pastink A; Vogel EW
    Mutat Res; 1996 Jun; 352(1-2):97-115. PubMed ID: 8676923
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Specificity of bischloroethylnitrosourea-induced mutation in a Chinese hamster ovary cell line transformed to express human O6-alkylguanine-DNA alkyltransferase.
    Minnick DT; Gerson SL; Dumenco LL; Veigl ML; Sedwick WD
    Cancer Res; 1993 Mar; 53(5):997-1003. PubMed ID: 8439973
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Expression of human O6-methylguanine-DNA methyltransferase in a DNA excision repair-deficient Chinese hamster ovary cell line and its response to certain alkylating agents.
    Wu ZN; Chan CL; Eastman A; Bresnick E
    Cancer Res; 1992 Jan; 52(1):32-5. PubMed ID: 1727384
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Modulation of ethylnitrosourea-induced toxicity and mutagenicity in human cells by O6-benzylguanine.
    Bronstein SM; Hooth MJ; Swenberg JA; Skopek TR
    Cancer Res; 1992 Jul; 52(14):3851-6. PubMed ID: 1617659
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutation spectra induced by alpha-acetoxytamoxifen-DNA adducts in human DNA repair proficient and deficient (xeroderma pigmentosum complementation group A) cells.
    McLuckie KI; Crookston RJ; Gaskell M; Farmer PB; Routledge MN; Martin EA; Brown K
    Biochemistry; 2005 Jun; 44(22):8198-205. PubMed ID: 15924439
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mutagenicity and mutational spectrum of N-methyl-N'-nitro-N-nitrosoguanidine in the hprt gene in G1-S and late S phase of diploid human fibroblasts.
    Yang JL; Lin JG; Hu MC; Wu CW
    Cancer Res; 1993 Jun; 53(12):2865-73. PubMed ID: 8504428
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DNA damage induced by a new 2-chloroethyl nitrosourea on malignant melanoma cells.
    Godeneche D; Rapp M; Thierry A; Laval F; Madelmont JC; Chollet P; Veyre A
    Cancer Res; 1990 Sep; 50(18):5898-903. PubMed ID: 2393861
    [TBL] [Abstract][Full Text] [Related]  

  • 15. O-ethylthymidine adducts are the most relevant damages for mutation induced by N-ethyl-N-nitrosourea in female germ cells of Drosophila melanogaster.
    Alvarez L; Comendador MA; Sierra LM
    Environ Mol Mutagen; 2002; 40(2):143-52. PubMed ID: 12203408
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effect of nucleotide excision repair on hprt gene mutations in rodent cells exposed to DNA ethylating agents.
    Op het Veld CW; van Hees-Stuivenberg S; van Zeeland AA; Jansen JG
    Mutagenesis; 1997 Nov; 12(6):417-24. PubMed ID: 9412994
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Potentiation of nitrosourea cytotoxicity in human leukemic cells by inactivation of O6-alkylguanine-DNA alkyltransferase.
    Gerson SL; Trey JE; Miller K
    Cancer Res; 1988 Mar; 48(6):1521-7. PubMed ID: 3162197
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effect of O6-methylguanine on DNA interstrand cross-link formation by chloroethylnitrosoureas and 2-chloroethyl(methylsulfonyl)methanesulfonate.
    Dolan ME; Pegg AE; Hora NK; Erickson LC
    Cancer Res; 1988 Jul; 48(13):3603-6. PubMed ID: 2837318
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Repair of O6-alkylguanine during DNA synthesis in murine bone marrow hematopoietic precursors.
    Gerson SL; Trey JE; Miller K; Benjamin E
    Cancer Res; 1987 Jan; 47(1):89-95. PubMed ID: 3539320
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Analysis of N-methyl-N-nitrosourea-induced mutations in a shuttle vector plasmid propagated in mouse O6-methylguanine-DNA methyltransferase-deficient cells in comparison with proficient cells.
    Moriwaki S; Yagi T; Nishigori C; Imamura S; Takebe H
    Cancer Res; 1991 Dec; 51(23 Pt 1):6219-23. PubMed ID: 1834328
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.