BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

402 related articles for article (PubMed ID: 16554355)

  • 1. N1-(3-cyclohexylbutanoyl)-N2-[3-(1H-imidazol-4-yl)propyl]guanidine (UR-AK57), a potent partial agonist for the human histamine H1- and H2-receptors.
    Xie SX; Kraus A; Ghorai P; Ye QZ; Elz S; Buschauer A; Seifert R
    J Pharmacol Exp Ther; 2006 Jun; 317(3):1262-8. PubMed ID: 16554355
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of impromidine- and arpromidine-derived guanidines on recombinant human and guinea pig histamine H1 and H2 receptors.
    Xie SX; Schalkhausser F; Ye QZ; Seifert R; Buschauer A
    Arch Pharm (Weinheim); 2007 Jan; 340(1):9-16. PubMed ID: 17206612
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular basis for the selective interaction of synthetic agonists with the human histamine H1-receptor compared with the guinea pig H1-receptor.
    Strasser A; Wittmann HJ; Kunze M; Elz S; Seifert R
    Mol Pharmacol; 2009 Mar; 75(3):454-65. PubMed ID: 19047480
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Probing ligand-specific histamine H1- and H2-receptor conformations with NG-acylated Imidazolylpropylguanidines.
    Xie SX; Ghorai P; Ye QZ; Buschauer A; Seifert R
    J Pharmacol Exp Ther; 2006 Apr; 317(1):139-46. PubMed ID: 16394198
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Multiple differences in agonist and antagonist pharmacology between human and guinea pig histamine H1-receptor.
    Seifert R; Wenzel-Seifert K; Burckstummer T; Pertz HH; Schunack W; Dove S; Buschauer A; Elz S
    J Pharmacol Exp Ther; 2003 Jun; 305(3):1104-15. PubMed ID: 12626648
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mutations of Cys-17 and Ala-271 in the human histamine H2 receptor determine the species selectivity of guanidine-type agonists and increase constitutive activity.
    Preuss H; Ghorai P; Kraus A; Dove S; Buschauer A; Seifert R
    J Pharmacol Exp Ther; 2007 Jun; 321(3):975-82. PubMed ID: 17347323
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Acylguanidines as bioisosteres of guanidines: NG-acylated imidazolylpropylguanidines, a new class of histamine H2 receptor agonists.
    Ghorai P; Kraus A; Keller M; Götte C; Igel P; Schneider E; Schnell D; Bernhardt G; Dove S; Zabel M; Elz S; Seifert R; Buschauer A
    J Med Chem; 2008 Nov; 51(22):7193-204. PubMed ID: 18950149
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Distinct interaction of human and guinea pig histamine H2-receptor with guanidine-type agonists.
    Kelley MT; Bürckstümmer T; Wenzel-Seifert K; Dove S; Buschauer A; Seifert R
    Mol Pharmacol; 2001 Dec; 60(6):1210-25. PubMed ID: 11723228
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Constitutive activity and ligand selectivity of human, guinea pig, rat, and canine histamine H2 receptors.
    Preuss H; Ghorai P; Kraus A; Dove S; Buschauer A; Seifert R
    J Pharmacol Exp Ther; 2007 Jun; 321(3):983-95. PubMed ID: 17332265
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and structure-activity relationships of cyanoguanidine-type and structurally related histamine H4 receptor agonists.
    Igel P; Geyer R; Strasser A; Dove S; Seifert R; Buschauer A
    J Med Chem; 2009 Oct; 52(20):6297-313. PubMed ID: 19791743
    [TBL] [Abstract][Full Text] [Related]  

  • 11. N(G)-acylated aminothiazolylpropylguanidines as potent and selective histamine H(2) receptor agonists.
    Kraus A; Ghorai P; Birnkammer T; Schnell D; Elz S; Seifert R; Dove S; Bernhardt G; Buschauer A
    ChemMedChem; 2009 Feb; 4(2):232-40. PubMed ID: 19072936
    [TBL] [Abstract][Full Text] [Related]  

  • 12. N(G)-acylated imidazolylpropylguanidines as potent histamine H4 receptor agonists: selectivity by variation of the N(G)-substituent.
    Igel P; Schneider E; Schnell D; Elz S; Seifert R; Buschauer A
    J Med Chem; 2009 Apr; 52(8):2623-7. PubMed ID: 19317445
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pharmacological profile of histaprodifens at four recombinant histamine H1 receptor species isoforms.
    Strasser A; Striegl B; Wittmann HJ; Seifert R
    J Pharmacol Exp Ther; 2008 Jan; 324(1):60-71. PubMed ID: 17928567
    [TBL] [Abstract][Full Text] [Related]  

  • 14. N(alpha)-imidazolylalkyl and pyridylalkyl derivatives of histaprodifen: synthesis and in vitro evaluation of highly potent histamine H(1)-receptor agonists.
    Menghin S; Pertz HH; Kramer K; Seifert R; Schunack W; Elz S
    J Med Chem; 2003 Dec; 46(25):5458-70. PubMed ID: 14640554
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Chiral NG-acylated hetarylpropylguanidine-type histamine H2 receptor agonists do not show significant stereoselectivity.
    Ghorai P; Kraus A; Birnkammer T; Geyer R; Bernhardt G; Dove S; Seifert R; Elz S; Buschauer A
    Bioorg Med Chem Lett; 2010 May; 20(10):3173-6. PubMed ID: 20409707
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The bivalent ligand approach leads to highly potent and selective acylguanidine-type histamine H₂ receptor agonists.
    Birnkammer T; Spickenreither A; Brunskole I; Lopuch M; Kagermeier N; Bernhardt G; Dove S; Seifert R; Elz S; Buschauer A
    J Med Chem; 2012 Feb; 55(3):1147-60. PubMed ID: 22216892
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Unexpected partial H1-receptor agonism of imidazole-type histamine H3-receptor antagonists lacking a basic side chain.
    Sadek B; Elz S; Pertz HH; Stark H; Schunack W
    Inflamm Res; 2004 Aug; 53 Suppl 2():S109-15. PubMed ID: 15338060
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Similar apparent constitutive activity of human histamine H(2)-receptor fused to long and short splice variants of G(salpha).
    Wenzel-Seifert K; Kelley MT; Buschauer A; Seifert R
    J Pharmacol Exp Ther; 2001 Dec; 299(3):1013-20. PubMed ID: 11714890
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Point mutations in the second extracellular loop of the histamine H2 receptor do not affect the species-selective activity of guanidine-type agonists.
    Preuss H; Ghorai P; Kraus A; Dove S; Buschauer A; Seifert R
    Naunyn Schmiedebergs Arch Pharmacol; 2007 Dec; 376(4):253-64. PubMed ID: 17999052
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dimeric carbamoylguanidine-type histamine H2 receptor ligands: A new class of potent and selective agonists.
    Kagermeier N; Werner K; Keller M; Baumeister P; Bernhardt G; Seifert R; Buschauer A
    Bioorg Med Chem; 2015 Jul; 23(14):3957-69. PubMed ID: 25639885
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.