504 related articles for article (PubMed ID: 16556651)
1. Effect of S5P alpha-helix charge mutants on inactivation of hERG K+ channels.
Clarke CE; Hill AP; Zhao J; Kondo M; Subbiah RN; Campbell TJ; Vandenberg JI
J Physiol; 2006 Jun; 573(Pt 2):291-304. PubMed ID: 16556651
[TBL] [Abstract][Full Text] [Related]
2. Structure of the HERG K+ channel S5P extracellular linker: role of an amphipathic alpha-helix in C-type inactivation.
Torres AM; Bansal PS; Sunde M; Clarke CE; Bursill JA; Smith DJ; Bauskin A; Breit SN; Campbell TJ; Alewood PF; Kuchel PW; Vandenberg JI
J Biol Chem; 2003 Oct; 278(43):42136-48. PubMed ID: 12902341
[TBL] [Abstract][Full Text] [Related]
3. Molecular basis of slow activation of the human ether-a-go-go related gene potassium channel.
Subbiah RN; Clarke CE; Smith DJ; Zhao J; Campbell TJ; Vandenberg JI
J Physiol; 2004 Jul; 558(Pt 2):417-31. PubMed ID: 15181157
[TBL] [Abstract][Full Text] [Related]
4. Linkage between 'disruption of inactivation' and 'reduction of K+ selectivity' among hERG mutants in the S5-P linker region.
Tseng GN
J Physiol; 2006 Nov; 577(Pt 1):459-60; author reply 461-2. PubMed ID: 17108185
[No Abstract] [Full Text] [Related]
5. Position of aromatic residues in the S6 domain, not inactivation, dictates cisapride sensitivity of HERG and eag potassium channels.
Chen J; Seebohm G; Sanguinetti MC
Proc Natl Acad Sci U S A; 2002 Sep; 99(19):12461-6. PubMed ID: 12209010
[TBL] [Abstract][Full Text] [Related]
6. Effects of outer mouth mutations on hERG channel function: a comparison with similar mutations in the Shaker channel.
Fan JS; Jiang M; Dun W; McDonald TV; Tseng GN
Biophys J; 1999 Jun; 76(6):3128-40. PubMed ID: 10354437
[TBL] [Abstract][Full Text] [Related]
7. The eag domain regulates hERG channel inactivation gating via a direct interaction.
Gustina AS; Trudeau MC
J Gen Physiol; 2013 Feb; 141(2):229-41. PubMed ID: 23319729
[TBL] [Abstract][Full Text] [Related]
8. Differential effects of amino-terminal distal and proximal domains in the regulation of human erg K(+) channel gating.
Viloria CG; Barros F; Giráldez T; Gómez-Varela D; de la Peña P
Biophys J; 2000 Jul; 79(1):231-46. PubMed ID: 10866950
[TBL] [Abstract][Full Text] [Related]
9. Tryptophan scanning mutagenesis of the HERG K+ channel: the S4 domain is loosely packed and likely to be lipid exposed.
Subbiah RN; Kondo M; Campbell TJ; Vandenberg JI
J Physiol; 2005 Dec; 569(Pt 2):367-79. PubMed ID: 16166152
[TBL] [Abstract][Full Text] [Related]
10. Structural and functional role of the extracellular s5-p linker in the HERG potassium channel.
Liu J; Zhang M; Jiang M; Tseng GN
J Gen Physiol; 2002 Nov; 120(5):723-37. PubMed ID: 12407082
[TBL] [Abstract][Full Text] [Related]
11. Mechanistic insight into human ether-à-go-go-related gene (hERG) K+ channel deactivation gating from the solution structure of the EAG domain.
Muskett FW; Thouta S; Thomson SJ; Bowen A; Stansfeld PJ; Mitcheson JS
J Biol Chem; 2011 Feb; 286(8):6184-91. PubMed ID: 21135103
[TBL] [Abstract][Full Text] [Related]
12. S641 contributes HERG K+ channel inactivation.
Bian JS; Cui J; Melman Y; McDonald TV
Cell Biochem Biophys; 2004; 41(1):25-40. PubMed ID: 15371638
[TBL] [Abstract][Full Text] [Related]
13. Transfer of rapid inactivation and sensitivity to the class III antiarrhythmic drug E-4031 from HERG to M-eag channels.
Herzberg IM; Trudeau MC; Robertson GA
J Physiol; 1998 Aug; 511 ( Pt 1)(Pt 1):3-14. PubMed ID: 9679158
[TBL] [Abstract][Full Text] [Related]
14. Two mutations at different positions in the CNBH domain of the hERG channel accelerate deactivation and impair the interaction with the EAG domain.
Kume S; Shimomura T; Tateyama M; Kubo Y
J Physiol; 2018 Oct; 596(19):4629-4650. PubMed ID: 30086184
[TBL] [Abstract][Full Text] [Related]
15. Mutations within the S4-S5 linker alter voltage sensor constraints in hERG K+ channels.
Van Slyke AC; Rezazadeh S; Snopkowski M; Shi P; Allard CR; Claydon TW
Biophys J; 2010 Nov; 99(9):2841-52. PubMed ID: 21044581
[TBL] [Abstract][Full Text] [Related]
16. Structural determinants of HERG channel block by clofilium and ibutilide.
Perry M; de Groot MJ; Helliwell R; Leishman D; Tristani-Firouzi M; Sanguinetti MC; Mitcheson J
Mol Pharmacol; 2004 Aug; 66(2):240-9. PubMed ID: 15266014
[TBL] [Abstract][Full Text] [Related]
17. Interaction simulation of hERG K+ channel with its specific BeKm-1 peptide: insights into the selectivity of molecular recognition.
Yi H; Cao Z; Yin S; Dai C; Wu Y; Li W
J Proteome Res; 2007 Feb; 6(2):611-20. PubMed ID: 17269718
[TBL] [Abstract][Full Text] [Related]
18. The pore domain outer helix contributes to both activation and inactivation of the HERG K+ channel.
Ju P; Pages G; Riek RP; Chen PC; Torres AM; Bansal PS; Kuyucak S; Kuchel PW; Vandenberg JI
J Biol Chem; 2009 Jan; 284(2):1000-8. PubMed ID: 18996846
[TBL] [Abstract][Full Text] [Related]
19. Direct interaction of eag domains and cyclic nucleotide-binding homology domains regulate deactivation gating in hERG channels.
Gianulis EC; Liu Q; Trudeau MC
J Gen Physiol; 2013 Oct; 142(4):351-66. PubMed ID: 24043860
[TBL] [Abstract][Full Text] [Related]
20. The neutral, hydrophobic isoleucine at position I521 in the extracellular S4 domain of hERG contributes to channel gating equilibrium.
Dou Y; Goodchild SJ; Velde RV; Wu Y; Fedida D
Am J Physiol Cell Physiol; 2013 Aug; 305(4):C468-78. PubMed ID: 23761630
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
