108 related articles for article (PubMed ID: 16564186)
1. Use of arterially perfused rabbit ventricular wedge in predicting arrhythmogenic potentials of drugs.
Chen X; Cordes JS; Bradley JA; Sun Z; Zhou J
J Pharmacol Toxicol Methods; 2006; 54(3):261-72. PubMed ID: 16564186
[TBL] [Abstract][Full Text] [Related]
2. Review of the predictive value of the Langendorff heart model (Screenit system) in assessing the proarrhythmic potential of drugs.
Valentin JP; Hoffmann P; De Clerck F; Hammond TG; Hondeghem L
J Pharmacol Toxicol Methods; 2004; 49(3):171-81. PubMed ID: 15172013
[TBL] [Abstract][Full Text] [Related]
3. In-vitro experimental models for the risk assessment of antibiotic-induced QT prolongation.
Lu HR; Vlaminckx E; Van de Water A; Rohrbacher J; Hermans A; Gallacher DJ
Eur J Pharmacol; 2006 Dec; 553(1-3):229-39. PubMed ID: 17054943
[TBL] [Abstract][Full Text] [Related]
4. Phase 2 early afterdepolarization as a trigger of polymorphic ventricular tachycardia in acquired long-QT syndrome : direct evidence from intracellular recordings in the intact left ventricular wall.
Yan GX; Wu Y; Liu T; Wang J; Marinchak RA; Kowey PR
Circulation; 2001 Jun; 103(23):2851-6. PubMed ID: 11401944
[TBL] [Abstract][Full Text] [Related]
5. Assessment of the proarrhythmic potential of the novel antiarrhythmic agent AZD7009 and dofetilide in experimental models of torsades de pointes.
Wu Y; Carlsson L; Liu T; Kowey PR; Yan GX
J Cardiovasc Electrophysiol; 2005 Aug; 16(8):898-904. PubMed ID: 16101634
[TBL] [Abstract][Full Text] [Related]
6. Assessment of drug-induced proarrhythmia: The importance of study design in the rabbit left ventricular wedge model.
Lu HR; Gallacher DJ; Yan GX
J Pharmacol Toxicol Methods; 2016; 81():151-60. PubMed ID: 27374776
[TBL] [Abstract][Full Text] [Related]
7. Nonclinical proarrhythmia models: predicting Torsades de Pointes.
Lawrence CL; Pollard CE; Hammond TG; Valentin JP
J Pharmacol Toxicol Methods; 2005; 52(1):46-59. PubMed ID: 15975832
[TBL] [Abstract][Full Text] [Related]
8. Severe proarrhythmic potential of risperidone compared to quetiapine in an experimental whole-heart model of proarrhythmia.
Frommeyer G; von der Ahe H; Brücher B; Dechering DG; Lange PS; Reinke F; Wasmer K; Köbe J; Pott C; Mönnig G; Eckardt L
Naunyn Schmiedebergs Arch Pharmacol; 2016 Oct; 389(10):1073-80. PubMed ID: 27405774
[TBL] [Abstract][Full Text] [Related]
9. QT prolongation and proarrhythmia by moxifloxacin: concordance of preclinical models in relation to clinical outcome.
Chen X; Cass JD; Bradley JA; Dahm CM; Sun Z; Kadyszewski E; Engwall MJ; Zhou J
Br J Pharmacol; 2005 Nov; 146(6):792-9. PubMed ID: 16158069
[TBL] [Abstract][Full Text] [Related]
10. The canine Purkinje fiber: an in vitro model system for acquired long QT syndrome and drug-induced arrhythmogenesis.
Gintant GA; Limberis JT; McDermott JS; Wegner CD; Cox BF
J Cardiovasc Pharmacol; 2001 May; 37(5):607-18. PubMed ID: 11336111
[TBL] [Abstract][Full Text] [Related]
11. Choice of cardiac tissue plays an important role in the evaluation of drug-induced prolongation of the QT interval in vitro in rabbit.
Lu HR; Vlaminckx E; Teisman A; Gallacher DJ
J Pharmacol Toxicol Methods; 2005; 52(1):90-105. PubMed ID: 15978848
[TBL] [Abstract][Full Text] [Related]
12. Blinded validation of the isolated arterially perfused rabbit ventricular wedge in preclinical assessment of drug-induced proarrhythmias.
Liu T; Brown BS; Wu Y; Antzelevitch C; Kowey PR; Yan GX
Heart Rhythm; 2006 Aug; 3(8):948-56. PubMed ID: 16876745
[TBL] [Abstract][Full Text] [Related]
13. Cisapride-induced transmural dispersion of repolarization and torsade de pointes in the canine left ventricular wedge preparation during epicardial stimulation.
Di Diego JM; Belardinelli L; Antzelevitch C
Circulation; 2003 Aug; 108(8):1027-33. PubMed ID: 12912819
[TBL] [Abstract][Full Text] [Related]
14. Prolonged action potential durations, increased dispersion of repolarization, and polymorphic ventricular tachycardia in a mouse model of proarrhythmia.
Fabritz L; Kirchhof P; Franz MR; Eckardt L; Mönnig G; Milberg P; Breithardt G; Haverkamp W
Basic Res Cardiol; 2003 Feb; 98(1):25-32. PubMed ID: 12494266
[TBL] [Abstract][Full Text] [Related]
15. Transmural dispersion of repolarization as a preclinical marker of drug-induced proarrhythmia.
Said TH; Wilson LD; Jeyaraj D; Fossa AA; Rosenbaum DS
J Cardiovasc Pharmacol; 2012 Aug; 60(2):165-71. PubMed ID: 22561361
[TBL] [Abstract][Full Text] [Related]
16. Dog left ventricular midmyocardial myocytes for assessment of drug-induced delayed repolarization: short-term variability and proarrhythmic potential.
Abi-Gerges N; Valentin JP; Pollard CE
Br J Pharmacol; 2010 Jan; 159(1):77-92. PubMed ID: 19663882
[TBL] [Abstract][Full Text] [Related]
17. Selective block of IKs plays a significant role in MAP triangulation induced by IKr block in isolated rabbit heart.
Guérard NC; Traebert M; Suter W; Dumotier BM
J Pharmacol Toxicol Methods; 2008; 58(1):32-40. PubMed ID: 18582585
[TBL] [Abstract][Full Text] [Related]
18. Preclinical strategies to assess QT liability and torsadogenic potential of new drugs: the role of experimental models.
Joshi A; Dimino T; Vohra Y; Cui C; Yan GX
J Electrocardiol; 2004; 37 Suppl():7-14. PubMed ID: 15534787
[TBL] [Abstract][Full Text] [Related]
19. Proarrhythmia as a class effect of quinolones: increased dispersion of repolarization and triangulation of action potential predict torsades de pointes.
Milberg P; Hilker E; Ramtin S; Cakir Y; Stypmann J; Engelen MA; Mönnig G; Osada N; Breithardt G; Haverkamp W; Eckardt L
J Cardiovasc Electrophysiol; 2007 Jun; 18(6):647-54. PubMed ID: 17388913
[TBL] [Abstract][Full Text] [Related]
20. Ventricular rate adaptation: a novel, rapid, cellular-based in-vitro assay to identify proarrhythmic and torsadogenic compounds.
Green JR; Diaz GJ; Limberis JT; Houseman KA; Su Z; Martin RL; Cox BF; Kantor S; Gintant GA
J Pharmacol Toxicol Methods; 2011; 64(1):68-73. PubMed ID: 21440075
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
