BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

151 related articles for article (PubMed ID: 16565079)

  • 1. Metalloprotease inhibitors GM6001 and TAPI-0 inhibit the obligate intracellular human pathogen Chlamydia trachomatis by targeting peptide deformylase of the bacterium.
    Balakrishnan A; Patel B; Sieber SA; Chen D; Pachikara N; Zhong G; Cravatt BF; Fan H
    J Biol Chem; 2006 Jun; 281(24):16691-9. PubMed ID: 16565079
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Non-coding nucleotides and amino acids near the active site regulate peptide deformylase expression and inhibitor susceptibility in Chlamydia trachomatis.
    Bao X; Pachikara ND; Oey CB; Balakrishnan A; Westblade LF; Tan M; Chase T; Nickels BE; Fan H
    Microbiology (Reading); 2011 Sep; 157(Pt 9):2569-2581. PubMed ID: 21719536
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of chlamydial infection in the genital tract of female mice by topical application of a peptide deformylase inhibitor.
    Balakrishnan A; Wang L; Li X; Ohman-Strickland P; Malatesta P; Fan H
    Microbiol Res; 2009; 164(3):338-46. PubMed ID: 17936604
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Antibiotic activity and characterization of BB-3497, a novel peptide deformylase inhibitor.
    Clements JM; Beckett RP; Brown A; Catlin G; Lobell M; Palan S; Thomas W; Whittaker M; Wood S; Salama S; Baker PJ; Rodgers HF; Barynin V; Rice DW; Hunter MG
    Antimicrob Agents Chemother; 2001 Feb; 45(2):563-70. PubMed ID: 11158755
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Peptide deformylase inhibitors with retro-amide scaffold: synthesis and structure-activity relationships.
    Lee SK; Choi KH; Lee SJ; Suh SW; Kim BM; Lee BJ
    Bioorg Med Chem Lett; 2010 Aug; 20(15):4317-9. PubMed ID: 20615695
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Enhanced potency of the metalloprotease inhibitor TAPI-2 by multivalent display.
    Raissi AJ; Scangarello FA; Hulce KR; Pontrello JK; Paradis S
    Bioorg Med Chem Lett; 2014 Apr; 24(8):2002-7. PubMed ID: 24581919
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ligand and Structure-Based Approaches for the Identification of Peptide Deformylase Inhibitors as Antibacterial Drugs.
    Gao J; Liang L; Zhu Y; Qiu S; Wang T; Zhang L
    Int J Mol Sci; 2016 Jul; 17(7):. PubMed ID: 27428963
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Peptide deformylase inhibitors with non-peptide scaffold: synthesis and structure-activity relationships.
    Lee SK; Choi KH; Lee SJ; Lee JS; Park JY; Kim BM; Lee BJ
    Bioorg Med Chem Lett; 2011 Jan; 21(1):133-6. PubMed ID: 21146987
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Actinonin, a naturally occurring antibacterial agent, is a potent deformylase inhibitor.
    Chen DZ; Patel DV; Hackbarth CJ; Wang W; Dreyer G; Young DC; Margolis PS; Wu C; Ni ZJ; Trias J; White RJ; Yuan Z
    Biochemistry; 2000 Feb; 39(6):1256-62. PubMed ID: 10684604
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Bacterial Peptide deformylase inhibitors: a new class of antibacterial agents.
    Jain R; Chen D; White RJ; Patel DV; Yuan Z
    Curr Med Chem; 2005; 12(14):1607-21. PubMed ID: 16022661
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition and structure-activity studies of methionine hydroxamic acid derivatives with bacterial peptide deformylase.
    Grant SK; Green BG; Kozarich JW
    Bioorg Chem; 2001 Aug; 29(4):211-22. PubMed ID: 16256693
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Human mitochondrial peptide deformylase, a new anticancer target of actinonin-based antibiotics.
    Lee MD; She Y; Soskis MJ; Borella CP; Gardner JR; Hayes PA; Dy BM; Heaney ML; Philips MR; Bornmann WG; Sirotnak FM; Scheinberg DA
    J Clin Invest; 2004 Oct; 114(8):1107-16. PubMed ID: 15489958
    [TBL] [Abstract][Full Text] [Related]  

  • 13. N-alkyl urea hydroxamic acids as a new class of peptide deformylase inhibitors with antibacterial activity.
    Hackbarth CJ; Chen DZ; Lewis JG; Clark K; Mangold JB; Cramer JA; Margolis PS; Wang W; Koehn J; Wu C; Lopez S; Withers G; Gu H; Dunn E; Kulathila R; Pan SH; Porter WL; Jacobs J; Trias J; Patel DV; Weidmann B; White RJ; Yuan Z
    Antimicrob Agents Chemother; 2002 Sep; 46(9):2752-64. PubMed ID: 12183225
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dynamic energy dependency of
    Liang P; Rosas-Lemus M; Patel D; Fang X; Tuz K; Juárez O
    J Biol Chem; 2018 Jan; 293(2):510-522. PubMed ID: 29123027
    [No Abstract]   [Full Text] [Related]  

  • 15. Plasmid Negative Regulation of CPAF Expression Is Pgp4 Independent and Restricted to Invasive
    Patton MJ; Chen CY; Yang C; McCorrister S; Grant C; Westmacott G; Yuan XY; Ochoa E; Fariss R; Whitmire WM; Carlson JH; Caldwell HD; McClarty G
    mBio; 2018 Jan; 9(1):. PubMed ID: 29382731
    [No Abstract]   [Full Text] [Related]  

  • 16. Hydroxamic acid derivatives as potent peptide deformylase inhibitors and antibacterial agents.
    Apfel C; Banner DW; Bur D; Dietz M; Hirata T; Hubschwerlen C; Locher H; Page MG; Pirson W; Rossé G; Specklin JL
    J Med Chem; 2000 Jun; 43(12):2324-31. PubMed ID: 10882358
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of chlamydial T3SS inhibitors through virtual screening against T3SS ATPase.
    Grishin AV; Luyksaar SI; Kapotina LN; Kirsanov DD; Zayakin ES; Karyagina AS; Zigangirova NA
    Chem Biol Drug Des; 2018 Mar; 91(3):717-727. PubMed ID: 29068165
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Metalloprotease-dependent amphiregulin release mediates tumor necrosis factor-alpha-induced IL-8 secretion in the human airway epithelial cell line NCI-H292.
    Chokki M; Mitsuhashi H; Kamimura T
    Life Sci; 2006 May; 78(26):3051-7. PubMed ID: 16427093
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, Synthesis, and Biological Evaluation of Vanillin Hydroxamic Acid Derivatives as Novel Peptide Deformylase Inhibitors.
    Gao J; Qiu S; Liang L; Hao Z; Zhou Q; Wang F; Mou J; Lin Q
    Curr Comput Aided Drug Des; 2018; 14(1):95-101. PubMed ID: 28606047
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Chlamydial Lytic Exit from Host Cells Is Plasmid Regulated.
    Yang C; Starr T; Song L; Carlson JH; Sturdevant GL; Beare PA; Whitmire WM; Caldwell HD
    mBio; 2015 Nov; 6(6):e01648-15. PubMed ID: 26556273
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.