163 related articles for article (PubMed ID: 16565437)
1. The saponin-mediated enhanced uptake of targeted saporin-based drugs is strongly dependent on the saponin structure.
Bachran C; Sutherland M; Heisler I; Hebestreit P; Melzig MF; Fuchs H
Exp Biol Med (Maywood); 2006 Apr; 231(4):412-20. PubMed ID: 16565437
[TBL] [Abstract][Full Text] [Related]
2. Combined application of saponin and chimeric toxins drastically enhances the targeted cytotoxicity on tumor cells.
Heisler I; Sutherland M; Bachran C; Hebestreit P; Schnitger A; Melzig MF; Fuchs H
J Control Release; 2005 Aug; 106(1-2):123-37. PubMed ID: 15935506
[TBL] [Abstract][Full Text] [Related]
3. A simple method for isolation of Gypsophila saponins for the combined application of targeted toxins and saponins in tumor therapy.
Weng A; Bachran D; Görick C; Bachran C; Fuchs H; Melzig MF
Planta Med; 2009 Oct; 75(13):1421-2. PubMed ID: 19452437
[TBL] [Abstract][Full Text] [Related]
4. Enhancement of toxicity of saporin-based toxins by Gypsophila saponins--kinetic of the saponin.
Weng A; Görick C; Melzig MF
Exp Biol Med (Maywood); 2009 Aug; 234(8):961-6. PubMed ID: 19491365
[TBL] [Abstract][Full Text] [Related]
5. Electrophoretic isolation of saponin fractions from Saponinum album and their evaluation in synergistically enhancing the receptor-specific cytotoxicity of targeted toxins.
Thakur M; Weng A; Bachran D; Riese SB; Böttger S; Melzig MF; Fuchs H
Electrophoresis; 2011 Nov; 32(21):3085-9. PubMed ID: 21997431
[TBL] [Abstract][Full Text] [Related]
6. The toxin component of targeted anti-tumor toxins determines their efficacy increase by saponins.
Weng A; Thakur M; Beceren-Braun F; Bachran D; Bachran C; Riese SB; Jenett-Siems K; Gilabert-Oriol R; Melzig MF; Fuchs H
Mol Oncol; 2012 Jun; 6(3):323-32. PubMed ID: 22309811
[TBL] [Abstract][Full Text] [Related]
7. The distribution of saponins in vivo affects their synergy with chimeric toxins against tumours expressing human epidermal growth factor receptors in mice.
Bachran C; Weng A; Bachran D; Riese SB; Schellmann N; Melzig MF; Fuchs H
Br J Pharmacol; 2010 Jan; 159(2):345-52. PubMed ID: 20015087
[TBL] [Abstract][Full Text] [Related]
8. Enhancement of saporin cytotoxicity by Gypsophila saponins--more than stimulation of endocytosis.
Weng A; Bachran C; Fuchs H; Krause E; Stephanowitz H; Melzig MF
Chem Biol Interact; 2009 Oct; 181(3):424-9. PubMed ID: 19615984
[TBL] [Abstract][Full Text] [Related]
9. Triterpenoid saponin augmention of saporin-based immunotoxin cytotoxicity for human leukaemia and lymphoma cells is partially immunospecific and target molecule dependent.
Holmes SE; Bachran C; Fuchs H; Weng A; Melzig MF; Flavell SU; Flavell DJ
Immunopharmacol Immunotoxicol; 2015 Feb; 37(1):42-55. PubMed ID: 25347443
[TBL] [Abstract][Full Text] [Related]
10. Augmentation of Saporin-Based Immunotoxins for Human Leukaemia and Lymphoma Cells by Triterpenoid Saponins: The Modifying Effects of Small Molecule Pharmacological Agents.
Smith WS; Johnston DA; Holmes SE; Wensley HJ; Flavell SU; Flavell DJ
Toxins (Basel); 2019 Feb; 11(2):. PubMed ID: 30791598
[TBL] [Abstract][Full Text] [Related]
11. Liquid-chromatographic profiling of Saponinum album (Merck).
Weng A; Thakur M; Schindler A; Fuchs H; Melzig MF
Pharmazie; 2011 Oct; 66(10):744-6. PubMed ID: 22026154
[TBL] [Abstract][Full Text] [Related]
12. Epidermal growth factor receptor expression affects the efficacy of the combined application of saponin and a targeted toxin on human cervical carcinoma cells.
Bachran D; Schneider S; Bachran C; Urban R; Weng A; Melzig MF; Hoffmann C; Kaufmann AM; Fuchs H
Int J Cancer; 2010 Sep; 127(6):1453-61. PubMed ID: 20020492
[TBL] [Abstract][Full Text] [Related]
13. Saponins from Saponaria officinalis L. Augment the Efficacy of a Rituximab-Immunotoxin.
Gilabert-Oriol R; Thakur M; Haussmann K; Niesler N; Bhargava C; Görick C; Fuchs H; Weng A
Planta Med; 2016 Dec; 82(18):1525-1531. PubMed ID: 27392242
[TBL] [Abstract][Full Text] [Related]
14. Inhibition of tumor growth by targeted toxins in mice is dramatically improved by saponinum album in a synergistic way.
Bachran C; Dürkop H; Sutherland M; Bachran D; Müller C; Weng A; Melzig MF; Fuchs H
J Immunother; 2009 Sep; 32(7):713-25. PubMed ID: 19561537
[TBL] [Abstract][Full Text] [Related]
15. The endocytic uptake pathways of targeted toxins are influenced by synergistically acting Gypsophila saponins.
Bachran D; Schneider S; Bachran C; Weng A; Melzig MF; Fuchs H
Mol Pharm; 2011 Dec; 8(6):2262-72. PubMed ID: 21981719
[TBL] [Abstract][Full Text] [Related]
16. Targeting tumor cells via EGF receptors: selective toxicity of an HBEGF-toxin fusion protein.
Chandler LA; Sosnowski BA; McDonald JR; Price JE; Aukerman SL; Baird A; Pierce GF; Houston LL
Int J Cancer; 1998 Sep; 78(1):106-11. PubMed ID: 9724101
[TBL] [Abstract][Full Text] [Related]
17. Membrane cholesterol is essential for triterpenoid saponin augmentation of a saporin-based immunotoxin directed against CD19 on human lymphoma cells.
Smith WS; Baker EJ; Holmes SE; Koster G; Hunt AN; Johnston DA; Flavell SU; Flavell DJ
Biochim Biophys Acta Biomembr; 2017 May; 1859(5):993-1007. PubMed ID: 28235471
[TBL] [Abstract][Full Text] [Related]
18. A cleavable adapter to reduce nonspecific cytotoxicity of recombinant immunotoxins.
Heisler I; Keller J; Tauber R; Sutherland M; Fuchs H
Int J Cancer; 2003 Jan; 103(2):277-82. PubMed ID: 12455044
[TBL] [Abstract][Full Text] [Related]
19. Analysis of Triterpenoid Saponins Reveals Insights into Structural Features Associated with Potent Protein Drug Enhancement Effects.
Cao XW; Wang FJ; Liew OW; Lu YZ; Zhao J
Mol Pharm; 2020 Feb; 17(2):683-694. PubMed ID: 31913047
[TBL] [Abstract][Full Text] [Related]
20. Enhancement of cytotoxicity of ribosome-inactivating-protein type I by saponinum album is not based on stimulation of phagocytosis.
Weng A; Jenett-Siems K; Görick C; Melzig MF
J Pharm Pharmacol; 2008 Jul; 60(7):925-30. PubMed ID: 18549680
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
