BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

317 related articles for article (PubMed ID: 16569023)

  • 1. Efficient ribosomal peptidyl transfer critically relies on the presence of the ribose 2'-OH at A2451 of 23S rRNA.
    Erlacher MD; Lang K; Wotzel B; Rieder R; Micura R; Polacek N
    J Am Chem Soc; 2006 Apr; 128(13):4453-9. PubMed ID: 16569023
    [TBL] [Abstract][Full Text] [Related]  

  • 2. An intact ribose moiety at A2602 of 23S rRNA is key to trigger peptidyl-tRNA hydrolysis during translation termination.
    Amort M; Wotzel B; Bakowska-Zywicka K; Erlacher MD; Micura R; Polacek N
    Nucleic Acids Res; 2007; 35(15):5130-40. PubMed ID: 17660192
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ribosomal peptidyl transferase can withstand mutations at the putative catalytic nucleotide.
    Polacek N; Gaynor M; Yassin A; Mankin AS
    Nature; 2001 May; 411(6836):498-501. PubMed ID: 11373685
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Chemical engineering of the peptidyl transferase center reveals an important role of the 2'-hydroxyl group of A2451.
    Erlacher MD; Lang K; Shankaran N; Wotzel B; Hüttenhofer A; Micura R; Mankin AS; Polacek N
    Nucleic Acids Res; 2005; 33(5):1618-27. PubMed ID: 15767286
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutations at nucleotides G2251 and U2585 of 23 S rRNA perturb the peptidyl transferase center of the ribosome.
    Green R; Samaha RR; Noller HF
    J Mol Biol; 1997 Feb; 266(1):40-50. PubMed ID: 9054969
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Fine structure of the peptidyl transferase centre on 23 S-like rRNAs deduced from chemical probing of antibiotic-ribosome complexes.
    Rodriguez-Fonseca C; Amils R; Garrett RA
    J Mol Biol; 1995 Mar; 247(2):224-35. PubMed ID: 7707371
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 23S rRNA similarity from selection for peptidyl transferase mimicry.
    Welch M; Majerfeld I; Yarus M
    Biochemistry; 1997 Jun; 36(22):6614-23. PubMed ID: 9184141
    [TBL] [Abstract][Full Text] [Related]  

  • 8. pKa of adenine 2451 in the ribosomal peptidyl transferase center remains elusive.
    Xiong L; Polacek N; Sander P; Böttger EC; Mankin A
    RNA; 2001 Oct; 7(10):1365-9. PubMed ID: 11680840
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A base pair between tRNA and 23S rRNA in the peptidyl transferase centre of the ribosome.
    Samaha RR; Green R; Noller HF
    Nature; 1995 Sep; 377(6547):309-14. PubMed ID: 7566085
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutations at position A960 of E. coli 23 S ribosomal RNA influence the structure of 5 S ribosomal RNA and the peptidyltransferase region of 23 S ribosomal RNA.
    Sergiev PV; Bogdanov AA; Dahlberg AE; Dontsova O
    J Mol Biol; 2000 Jun; 299(2):379-89. PubMed ID: 10860746
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mutations in the conserved P loop perturb the conformation of two structural elements in the peptidyl transferase center of 23 S ribosomal RNA.
    Gregory ST; Dahlberg AE
    J Mol Biol; 1999 Jan; 285(4):1475-83. PubMed ID: 9917390
    [TBL] [Abstract][Full Text] [Related]  

  • 12. How ribosomes make peptide bonds.
    Rodnina MV; Beringer M; Wintermeyer W
    Trends Biochem Sci; 2007 Jan; 32(1):20-6. PubMed ID: 17157507
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Reconstitution of functional 50S ribosomes from in vitro transcripts of Bacillus stearothermophilus 23S rRNA.
    Green R; Noller HF
    Biochemistry; 1999 Feb; 38(6):1772-9. PubMed ID: 10026257
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The critical role of the universally conserved A2602 of 23S ribosomal RNA in the release of the nascent peptide during translation termination.
    Polacek N; Gomez MJ; Ito K; Xiong L; Nakamura Y; Mankin A
    Mol Cell; 2003 Jan; 11(1):103-12. PubMed ID: 12535525
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutational analysis of the donor substrate binding site of the ribosomal peptidyltransferase center.
    Saarma U; Spahn CM; Nierhaus KH; Remme J
    RNA; 1998 Feb; 4(2):189-94. PubMed ID: 9570318
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effect of antibiotics on large ribosomal subunit assembly reveals possible function of 5 S rRNA.
    Khaitovich P; Mankin AS
    J Mol Biol; 1999 Sep; 291(5):1025-34. PubMed ID: 10518940
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Probing functions of the ribosomal peptidyl transferase center by nucleotide analog interference.
    Erlacher MD; Polacek N
    Methods Mol Biol; 2012; 848():215-26. PubMed ID: 22315072
    [TBL] [Abstract][Full Text] [Related]  

  • 18. pH-dependent conformational flexibility within the ribosomal peptidyl transferase center.
    Muth GW; Chen L; Kosek AB; Strobel SA
    RNA; 2001 Oct; 7(10):1403-15. PubMed ID: 11680845
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The structure of helix 89 of 23S rRNA is important for peptidyl transferase function of Escherichia coli ribosome.
    Burakovsky DE; Sergiev PV; Steblyanko MA; Konevega AL; Bogdanov AA; Dontsova OA
    FEBS Lett; 2011 Oct; 585(19):3073-8. PubMed ID: 21875584
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of the ribosomal peptidyl transferase reaction by the mycarose moiety of the antibiotics carbomycin, spiramycin and tylosin.
    Poulsen SM; Kofoed C; Vester B
    J Mol Biol; 2000 Dec; 304(3):471-81. PubMed ID: 11090288
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.