416 related articles for article (PubMed ID: 16570161)
1. Intracellular amyloid-like deposits contain unprocessed pro-islet amyloid polypeptide (proIAPP) in beta cells of transgenic mice overexpressing the gene for human IAPP and transplanted human islets.
Paulsson JF; Andersson A; Westermark P; Westermark GT
Diabetologia; 2006 Jun; 49(6):1237-46. PubMed ID: 16570161
[TBL] [Abstract][Full Text] [Related]
2. Loss of prohormone convertase 2 promotes beta cell dysfunction in a rodent transplant model expressing human pro-islet amyloid polypeptide.
Courtade JA; Wang EY; Yen P; Dai DL; Soukhatcheva G; Orban PC; Verchere CB
Diabetologia; 2017 Mar; 60(3):453-463. PubMed ID: 27999871
[TBL] [Abstract][Full Text] [Related]
3. Dual role of interleukin-1β in islet amyloid formation and its β-cell toxicity: Implications for type 2 diabetes and islet transplantation.
Park YJ; Warnock GL; Ao Z; Safikhan N; Meloche M; Asadi A; Kieffer TJ; Marzban L
Diabetes Obes Metab; 2017 May; 19(5):682-694. PubMed ID: 28058779
[TBL] [Abstract][Full Text] [Related]
4. Formation of islet amyloid fibrils in beta-secretory granules of transgenic mice expressing human islet amyloid polypeptide/amylin.
Yagui K; Yamaguchi T; Kanatsuka A; Shimada F; Huang CI; Tokuyama Y; Ohsawa H; Yamamura K; Miyazaki J; Mikata A
Eur J Endocrinol; 1995 Apr; 132(4):487-96. PubMed ID: 7711888
[TBL] [Abstract][Full Text] [Related]
5. Pro islet amyloid polypeptide (ProIAPP) immunoreactivity in the islets of Langerhans.
Westermark GT; Steiner DF; Gebre-Medhin S; Engström U; Westermark P
Ups J Med Sci; 2000; 105(2):97-106. PubMed ID: 11095107
[TBL] [Abstract][Full Text] [Related]
6. Amyloidogenicity of recombinant human pro-islet amyloid polypeptide (ProIAPP).
Krampert M; Bernhagen J; Schmucker J; Horn A; Schmauder A; Brunner H; Voelter W; Kapurniotu A
Chem Biol; 2000 Nov; 7(11):855-71. PubMed ID: 11094339
[TBL] [Abstract][Full Text] [Related]
7. The prohormone convertase enzyme 2 (PC2) is essential for processing pro-islet amyloid polypeptide at the NH2-terminal cleavage site.
Wang J; Xu J; Finnerty J; Furuta M; Steiner DF; Verchere CB
Diabetes; 2001 Mar; 50(3):534-9. PubMed ID: 11246872
[TBL] [Abstract][Full Text] [Related]
8. Islet amyloid and type 2 diabetes: from molecular misfolding to islet pathophysiology.
Jaikaran ET; Clark A
Biochim Biophys Acta; 2001 Nov; 1537(3):179-203. PubMed ID: 11731221
[TBL] [Abstract][Full Text] [Related]
9. Characterization of the heparin binding site in the N-terminus of human pro-islet amyloid polypeptide: implications for amyloid formation.
Abedini A; Tracz SM; Cho JH; Raleigh DP
Biochemistry; 2006 Aug; 45(30):9228-37. PubMed ID: 16866369
[TBL] [Abstract][Full Text] [Related]
10. Inhibition of glycosaminoglycan-mediated amyloid formation by islet amyloid polypeptide and proIAPP processing intermediates.
Meng F; Raleigh DP
J Mol Biol; 2011 Feb; 406(3):491-502. PubMed ID: 21195086
[TBL] [Abstract][Full Text] [Related]
11. Processing of pro-islet amyloid polypeptide (proIAPP) by the prohormone convertase PC2.
Badman MK; Shennan KI; Jermany JL; Docherty K; Clark A
FEBS Lett; 1996 Jan; 378(3):227-31. PubMed ID: 8557106
[TBL] [Abstract][Full Text] [Related]
12. Processing of synthetic pro-islet amyloid polypeptide (proIAPP) 'amylin' by recombinant prohormone convertase enzymes, PC2 and PC3, in vitro.
Higham CE; Hull RL; Lawrie L; Shennan KI; Morris JF; Birch NP; Docherty K; Clark A
Eur J Biochem; 2000 Aug; 267(16):4998-5004. PubMed ID: 10931181
[TBL] [Abstract][Full Text] [Related]
13. Role of carboxypeptidase E in processing of pro-islet amyloid polypeptide in {beta}-cells.
Marzban L; Soukhatcheva G; Verchere CB
Endocrinology; 2005 Apr; 146(4):1808-17. PubMed ID: 15618358
[TBL] [Abstract][Full Text] [Related]
14. Impaired NH2-terminal processing of human proislet amyloid polypeptide by the prohormone convertase PC2 leads to amyloid formation and cell death.
Marzban L; Rhodes CJ; Steiner DF; Haataja L; Halban PA; Verchere CB
Diabetes; 2006 Aug; 55(8):2192-201. PubMed ID: 16873681
[TBL] [Abstract][Full Text] [Related]
15. Intra- and extracellular amyloid fibrils are formed in cultured pancreatic islets of transgenic mice expressing human islet amyloid polypeptide.
de Koning EJ; Morris ER; Hofhuis FM; Posthuma G; Höppener JW; Morris JF; Capel PJ; Clark A; Verbeek JS
Proc Natl Acad Sci U S A; 1994 Aug; 91(18):8467-71. PubMed ID: 8078905
[TBL] [Abstract][Full Text] [Related]
16. Role of beta-cell prohormone convertase (PC)1/3 in processing of pro-islet amyloid polypeptide.
Marzban L; Trigo-Gonzalez G; Zhu X; Rhodes CJ; Halban PA; Steiner DF; Verchere CB
Diabetes; 2004 Jan; 53(1):141-8. PubMed ID: 14693708
[TBL] [Abstract][Full Text] [Related]
17. Human islet amyloid polypeptide accumulates at similar sites in islets of transgenic mice and humans.
de Koning EJ; Höppener JW; Verbeek JS; Oosterwijk C; van Hulst KL; Baker CA; Lips CJ; Morris JF; Clark A
Diabetes; 1994 May; 43(5):640-4. PubMed ID: 8168639
[TBL] [Abstract][Full Text] [Related]
18. Processing of pro-islet amyloid polypeptide in the constitutive and regulated secretory pathways of beta cells.
Marzban L; Trigo-Gonzalez G; Verchere CB
Mol Endocrinol; 2005 Aug; 19(8):2154-63. PubMed ID: 15802374
[TBL] [Abstract][Full Text] [Related]
19. SORLA mediates endocytic uptake of proIAPP and protects against islet amyloid deposition.
Shih AZL; Chen YC; Speckmann T; Søndergaard E; Schürmann A; Verchere CB; Willnow TE
Mol Metab; 2022 Nov; 65():101585. PubMed ID: 36055578
[TBL] [Abstract][Full Text] [Related]
20. Aberrant processing of human proislet amyloid polypeptide results in increased amyloid formation.
Paulsson JF; Westermark GT
Diabetes; 2005 Jul; 54(7):2117-25. PubMed ID: 15983213
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
