BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

214 related articles for article (PubMed ID: 16570909)

  • 1. Nanomolar inhibitors of the peptidyl prolyl cis/trans isomerase Pin1 from combinatorial peptide libraries.
    Wildemann D; Erdmann F; Alvarez BH; Stoller G; Zhou XZ; Fanghänel J; Schutkowski M; Lu KP; Fischer G
    J Med Chem; 2006 Apr; 49(7):2147-50. PubMed ID: 16570909
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure-based design of novel human Pin1 inhibitors (I).
    Guo C; Hou X; Dong L; Dagostino E; Greasley S; Ferre R; Marakovits J; Johnson MC; Matthews D; Mroczkowski B; Parge H; Vanarsdale T; Popoff I; Piraino J; Margosiak S; Thomson J; Los G; Murray BW
    Bioorg Med Chem Lett; 2009 Oct; 19(19):5613-6. PubMed ID: 19729306
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Peroxide-mediated oxidation and inhibition of the peptidyl-prolyl isomerase Pin1.
    Innes BT; Sowole MA; Gyenis L; Dubinsky M; Konermann L; Litchfield DW; Brandl CJ; Shilton BH
    Biochim Biophys Acta; 2015 May; 1852(5):905-12. PubMed ID: 25595659
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A Selective, Cell-Permeable Nonphosphorylated Bicyclic Peptidyl Inhibitor against Peptidyl-Prolyl Isomerase Pin1.
    Jiang B; Pei D
    J Med Chem; 2015 Aug; 58(15):6306-12. PubMed ID: 26196061
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Substrate-based design of reversible Pin1 inhibitors.
    Zhang Y; Füssel S; Reimer U; Schutkowski M; Fischer G
    Biochemistry; 2002 Oct; 41(39):11868-77. PubMed ID: 12269831
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural basis for high-affinity peptide inhibition of human Pin1.
    Zhang Y; Daum S; Wildemann D; Zhou XZ; Verdecia MA; Bowman ME; Lücke C; Hunter T; Lu KP; Fischer G; Noel JP
    ACS Chem Biol; 2007 May; 2(5):320-8. PubMed ID: 17518432
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Peptidyl prolyl isomerase Pin1-inhibitory activity of D-glutamic and D-aspartic acid derivatives bearing a cyclic aliphatic amine moiety.
    Nakagawa H; Seike S; Sugimoto M; Ieda N; Kawaguchi M; Suzuki T; Miyata N
    Bioorg Med Chem Lett; 2015 Dec; 25(23):5619-24. PubMed ID: 26508545
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role of prolyl isomerase pin1 in pathogenesis of diseases and remedy for the diseases from natural products.
    Takahashi K; Shimizu T; Kosaka K; Hidaka M; Uchida C; Uchida T
    Curr Drug Targets; 2014; 15(10):973-81. PubMed ID: 25182609
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Preparation of protein transduction domain-fused peptidyl prolyl cis/trans isomerase Pin1.
    Ohashi T; Teshima S; Hidaka M; Uchida T
    Biosci Biotechnol Biochem; 2010; 74(10):2067-70. PubMed ID: 20944414
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Conformation-directed catalysis and coupled enzyme-substrate dynamics in Pin1 phosphorylation-dependent cis-trans isomerase.
    Velazquez HA; Hamelberg D
    J Phys Chem B; 2013 Oct; 117(39):11509-17. PubMed ID: 23980573
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An essential role for Pin1 in Xenopus laevis embryonic development revealed by specific inhibitors.
    Wildemann D; Hernandez Alvarez B; Stoller G; Zhou XZ; Lu KP; Erdmann F; Ferrari D; Fischer G
    Biol Chem; 2007 Oct; 388(10):1103-11. PubMed ID: 17937625
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cysteine-mediated dynamic hydrogen-bonding network in the active site of Pin1.
    Barman A; Hamelberg D
    Biochemistry; 2014 Jun; 53(23):3839-50. PubMed ID: 24840168
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular mechanisms of the phospho-dependent prolyl cis/trans isomerase Pin1.
    Lippens G; Landrieu I; Smet C
    FEBS J; 2007 Oct; 274(20):5211-22. PubMed ID: 17892493
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Prolyl isomerase, Pin1: new findings of post-translational modifications and physiological substrates in cancer, asthma and Alzheimer's disease.
    Takahashi K; Uchida C; Shin RW; Shimazaki K; Uchida T
    Cell Mol Life Sci; 2008 Feb; 65(3):359-75. PubMed ID: 17965833
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Aluminum(III) interferes with the structure and the activity of the peptidyl-prolyl cis-trans isomerase (Pin1): a new mechanism contributing to the pathogenesis of Alzheimer's disease and cancers?
    Wang JZ; Liu J; Lin T; Han YG; Luo Y; Xi L; Du LF
    J Inorg Biochem; 2013 Sep; 126():111-7. PubMed ID: 23806774
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Recent advances in the study of pin1 and its inhibitors].
    Zhang CJ; Zhang ZH; Xu BL; Wang YL
    Yao Xue Xue Bao; 2008 Jan; 43(1):9-17. PubMed ID: 18357725
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The peptidyl prolyl cis/trans-isomerase Pin1 recognizes the phospho-Thr212-Pro213 site on Tau.
    Smet C; Sambo AV; Wieruszeski JM; Leroy A; Landrieu I; Buée L; Lippens G
    Biochemistry; 2004 Feb; 43(7):2032-40. PubMed ID: 14967043
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A dual inhibitor against prolyl isomerase Pin1 and cyclophilin discovered by a novel real-time fluorescence detection method.
    Mori T; Hidaka M; Lin YC; Yoshizawa I; Okabe T; Egashira S; Kojima H; Nagano T; Koketsu M; Takamiya M; Uchida T
    Biochem Biophys Res Commun; 2011 Mar; 406(3):439-43. PubMed ID: 21333629
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Aryl indanyl ketones: efficient inhibitors of the human peptidyl prolyl cis/trans isomerase Pin1.
    Daum S; Erdmann F; Fischer G; Féaux de Lacroix B; Hessamian-Alinejad A; Houben S; Frank W; Braun M
    Angew Chem Int Ed Engl; 2006 Nov; 45(44):7454-8. PubMed ID: 17048295
    [No Abstract]   [Full Text] [Related]  

  • 20. Dipentamethylene thiuram monosulfide is a novel inhibitor of Pin1.
    Tatara Y; Lin YC; Bamba Y; Mori T; Uchida T
    Biochem Biophys Res Commun; 2009 Jul; 384(3):394-8. PubMed ID: 19422802
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.