BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

270 related articles for article (PubMed ID: 16571675)

  • 1. Involvement of Akt in ER-to-Golgi transport of SCAP/SREBP: a link between a key cell proliferative pathway and membrane synthesis.
    Du X; Kristiana I; Wong J; Brown AJ
    Mol Biol Cell; 2006 Jun; 17(6):2735-45. PubMed ID: 16571675
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Fatostatin blocks ER exit of SCAP but inhibits cell growth in a SCAP-independent manner.
    Shao W; Machamer CE; Espenshade PJ
    J Lipid Res; 2016 Aug; 57(8):1564-73. PubMed ID: 27324795
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Insulin enhances post-translational processing of nascent SREBP-1c by promoting its phosphorylation and association with COPII vesicles.
    Yellaturu CR; Deng X; Cagen LM; Wilcox HG; Mansbach CM; Siddiqi SA; Park EA; Raghow R; Elam MB
    J Biol Chem; 2009 Mar; 284(12):7518-32. PubMed ID: 19158095
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sterol regulatory element-binding protein (SREBP) cleavage regulates Golgi-to-endoplasmic reticulum recycling of SREBP cleavage-activating protein (SCAP).
    Shao W; Espenshade PJ
    J Biol Chem; 2014 Mar; 289(11):7547-57. PubMed ID: 24478315
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PAQR3 modulates cholesterol homeostasis by anchoring Scap/SREBP complex to the Golgi apparatus.
    Xu D; Wang Z; Zhang Y; Jiang W; Pan Y; Song BL; Chen Y
    Nat Commun; 2015 Aug; 6():8100. PubMed ID: 26311497
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Akt acutely activates the cholesterogenic transcription factor SREBP-2.
    Luu W; Sharpe LJ; Stevenson J; Brown AJ
    Biochim Biophys Acta; 2012 Feb; 1823(2):458-64. PubMed ID: 22005015
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activation of mTOR modulates SREBP-2 to induce foam cell formation through increased retinoblastoma protein phosphorylation.
    Ma KL; Liu J; Wang CX; Ni J; Zhang Y; Wu Y; Lv LL; Ruan XZ; Liu BC
    Cardiovasc Res; 2013 Dec; 100(3):450-60. PubMed ID: 24068000
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The sterol-sensing endoplasmic reticulum (ER) membrane protein TRC8 hampers ER to Golgi transport of sterol regulatory element-binding protein-2 (SREBP-2)/SREBP cleavage-activated protein and reduces SREBP-2 cleavage.
    Irisawa M; Inoue J; Ozawa N; Mori K; Sato R
    J Biol Chem; 2009 Oct; 284(42):28995-9004. PubMed ID: 19706601
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hepatitis C virus genotype-3a core protein enhances sterol regulatory element-binding protein-1 activity through the phosphoinositide 3-kinase-Akt-2 pathway.
    Jackel-Cram C; Qiao L; Xiang Z; Brownlie R; Zhou Y; Babiuk L; Liu Q
    J Gen Virol; 2010 Jun; 91(Pt 6):1388-95. PubMed ID: 20130133
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Assaying Sterol-Regulated ER-to-Golgi Transport of SREBP Cleavage-Activating Protein Using Immunofluorescence Microscopy.
    Ishida CT; Shao W; Espenshade PJ
    Methods Mol Biol; 2023; 2557():755-764. PubMed ID: 36512249
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Glutamine stimulates the gene expression and processing of sterol regulatory element binding proteins, thereby increasing the expression of their target genes.
    Inoue J; Ito Y; Shimada S; Satoh SI; Sasaki T; Hashidume T; Kamoshida Y; Shimizu M; Sato R
    FEBS J; 2011 Aug; 278(15):2739-50. PubMed ID: 21696544
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Reconstitution of sterol-regulated endoplasmic reticulum-to-Golgi transport of SREBP-2 in insect cells by co-expression of mammalian SCAP and Insigs.
    Dobrosotskaya IY; Goldstein JL; Brown MS; Rawson RB
    J Biol Chem; 2003 Sep; 278(37):35837-43. PubMed ID: 12842885
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis.
    Xu D; Wang Z; Xia Y; Shao F; Xia W; Wei Y; Li X; Qian X; Lee JH; Du L; Zheng Y; Lv G; Leu JS; Wang H; Xing D; Liang T; Hung MC; Lu Z
    Nature; 2020 Apr; 580(7804):530-535. PubMed ID: 32322062
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sterols regulate cycling of SREBP cleavage-activating protein (SCAP) between endoplasmic reticulum and Golgi.
    Nohturfft A; DeBose-Boyd RA; Scheek S; Goldstein JL; Brown MS
    Proc Natl Acad Sci U S A; 1999 Sep; 96(20):11235-40. PubMed ID: 10500160
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ring finger protein 5 activates sterol regulatory element-binding protein 2 (SREBP2) to promote cholesterol biosynthesis via inducing polyubiquitination of SREBP chaperone SCAP.
    Kuan YC; Takahashi Y; Maruyama T; Shimizu M; Yamauchi Y; Sato R
    J Biol Chem; 2020 Mar; 295(12):3918-3928. PubMed ID: 32054686
    [TBL] [Abstract][Full Text] [Related]  

  • 16. COPI-mediated retrieval of SCAP is crucial for regulating lipogenesis under basal and sterol-deficient conditions.
    Takashima K; Saitoh A; Funabashi T; Hirose S; Yagi C; Nozaki S; Sato R; Shin HW; Nakayama K
    J Cell Sci; 2015 Aug; 128(15):2805-15. PubMed ID: 26092941
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanisms of dysregulation of low-density lipoprotein receptor expression in HepG2 cells induced by inflammatory cytokines.
    Chen YX; Ruan XZ; Huang AL; Li Q; Moorhead JF; Varghese Z
    Chin Med J (Engl); 2007 Dec; 120(24):2185-90. PubMed ID: 18167199
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phosphatidylinositol 3-kinase/AKT pathway regulates the endoplasmic reticulum to golgi traffic of ceramide in glioma cells: a link between lipid signaling pathways involved in the control of cell survival.
    Giussani P; Brioschi L; Bassi R; Riboni L; Viani P
    J Biol Chem; 2009 Feb; 284(8):5088-96. PubMed ID: 19103588
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role for sterol regulatory element-binding protein in activation of endothelial cells by phospholipid oxidation products.
    Yeh M; Cole AL; Choi J; Liu Y; Tulchinsky D; Qiao JH; Fishbein MC; Dooley AN; Hovnanian T; Mouilleseaux K; Vora DK; Yang WP; Gargalovic P; Kirchgessner T; Shyy JY; Berliner JA
    Circ Res; 2004 Oct; 95(8):780-8. PubMed ID: 15388640
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER.
    Yang T; Espenshade PJ; Wright ME; Yabe D; Gong Y; Aebersold R; Goldstein JL; Brown MS
    Cell; 2002 Aug; 110(4):489-500. PubMed ID: 12202038
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.