198 related articles for article (PubMed ID: 16581270)
1. A novel approach to data processing of the QT interval response in the conscious telemetered beagle dog.
Ollerstam A; Persson AH; Visser SA; Fredriksson JM; Forsberg T; Nilsson LB; Eklund G; Wiklund SJ; Gabrielsson J; Duker G; Al-Saffar A
J Pharmacol Toxicol Methods; 2007; 55(1):35-48. PubMed ID: 16581270
[TBL] [Abstract][Full Text] [Related]
2. Comparison of the QT interval response during sinus and paced rhythm in conscious and anesthetized beagle dogs.
Ollerstam A; Visser SA; Duker G; Forsberg T; Persson AH; Nilsson LB; Björkman JA; Gabrielsson J; Al-Saffar A
J Pharmacol Toxicol Methods; 2007; 56(2):131-44. PubMed ID: 17689270
[TBL] [Abstract][Full Text] [Related]
3. Pharmacokinetic-pharmacodynamic modeling of drug-induced effect on the QT interval in conscious telemetered dogs.
Ollerstam A; Visser SA; Persson AH; Eklund G; Nilsson LB; Forsberg T; Wiklund SJ; Gabrielsson J; Duker G; Al-Saffar A
J Pharmacol Toxicol Methods; 2006; 53(2):174-83. PubMed ID: 16140023
[TBL] [Abstract][Full Text] [Related]
4. A novel predictive pharmacokinetic/pharmacodynamic model of repolarization prolongation derived from the effects of terfenadine, cisapride and E-4031 in the conscious chronic av node--ablated, His bundle-paced dog.
Nolan ER; Feng MR; Koup JR; Liu J; Turluck D; Zhang Y; Paulissen JB; Olivier NB; Miller T; Bailie MB
J Pharmacol Toxicol Methods; 2006; 53(1):1-10. PubMed ID: 16399550
[TBL] [Abstract][Full Text] [Related]
5. A highly sensitive canine telemetry model for detection of QT interval prolongation: studies with moxifloxacin, haloperidol and MK-499.
Chaves AA; Zingaro GJ; Yordy MA; Bustard KA; O'Sullivan S; Galijatovic-Idrizbegovic A; Schuck H; Christian DB; Hoe CM; Briscoe RJ
J Pharmacol Toxicol Methods; 2007; 56(2):103-14. PubMed ID: 17643323
[TBL] [Abstract][Full Text] [Related]
6. Calculation of QT shift in non clinical safety pharmacology studies.
Champeroux P; Martel E; Fowler JS; Maurin A; Sola ML; Jude S; Elamrani F; Weyn AA; Laveissiere A; Lala P; Richard S
J Pharmacol Toxicol Methods; 2009; 59(2):73-85. PubMed ID: 19135537
[TBL] [Abstract][Full Text] [Related]
7. Heart rate correction models to detect QT interval prolongation in novel pharmaceutical development.
Markert M; Shen R; Trautmann T; Guth B
J Pharmacol Toxicol Methods; 2011; 64(1):25-41. PubMed ID: 21635956
[TBL] [Abstract][Full Text] [Related]
8. Assessment of drug-induced QT interval prolongation in conscious rabbits.
Kijtawornrat A; Ozkanlar Y; Keene BW; Roche BM; Hamlin DM; Hamlin RL
J Pharmacol Toxicol Methods; 2006; 53(2):168-73. PubMed ID: 16290300
[TBL] [Abstract][Full Text] [Related]
9. Comparison of guinea-pig ventricular myocytes and dog Purkinje fibres for in vitro assessment of drug-induced delayed repolarization.
Terrar DA; Wilson CM; Graham SG; Bryant SM; Heath BM
J Pharmacol Toxicol Methods; 2007; 56(2):171-85. PubMed ID: 17596973
[TBL] [Abstract][Full Text] [Related]
10. The cardiovascular and pharmacokinetic profile of dofetilide in conscious telemetered beagle dogs and cynomolgus monkeys.
Haushalter TM; Friedrichs GS; Reynolds DL; Barecki-Roach M; Pastino G; Hayes R; Bass AS
Br J Pharmacol; 2008 Aug; 154(7):1457-64. PubMed ID: 18604237
[TBL] [Abstract][Full Text] [Related]
11. QT PRODACT: in vivo QT assay in the conscious dog for assessing the potential for QT interval prolongation by human pharmaceuticals.
Toyoshima S; Kanno A; Kitayama T; Sekiya K; Nakai K; Haruna M; Mino T; Miyazaki H; Yano K; Yamamoto K
J Pharmacol Sci; 2005; 99(5):459-71. PubMed ID: 16493187
[TBL] [Abstract][Full Text] [Related]
12. Measurements of blood pressure and electrocardiogram in conscious freely moving guineapigs: a model for screening QT interval prolongation effects.
Hess P; Rey M; Wanner D; Steiner B; Clozel M
Lab Anim; 2007 Oct; 41(4):470-80. PubMed ID: 17988441
[TBL] [Abstract][Full Text] [Related]
13. The relationship of clinical QT prolongation to outcome in the conscious dog using a beat-to-beat QT-RR interval assessment.
Fossa AA; DePasquale MJ; Raunig DL; Avery MJ; Leishman DJ
J Pharmacol Exp Ther; 2002 Aug; 302(2):828-33. PubMed ID: 12130750
[TBL] [Abstract][Full Text] [Related]
14. Pharmacokinetic-pharmacodynamic modeling of QRS-prolongation by flecainide: heart rate-dependent effects during sinus rhythm in conscious telemetered dogs.
Sällström J; Al-Saffar A; Pehrson R
J Pharmacol Toxicol Methods; 2014; 69(1):24-9. PubMed ID: 24140388
[TBL] [Abstract][Full Text] [Related]
15. Correction of QT values to allow for increases in heart rate in conscious Beagle dogs in toxicology assessment.
Tattersall ML; Dymond M; Hammond T; Valentin JP
J Pharmacol Toxicol Methods; 2006; 53(1):11-9. PubMed ID: 15886026
[TBL] [Abstract][Full Text] [Related]
16. Translational pharmacokinetic-pharmacodynamic modeling of QTc effects in dog and human.
Parkinson J; Visser SA; Jarvis P; Pollard C; Valentin JP; Yates JW; Ewart L
J Pharmacol Toxicol Methods; 2013; 68(3):357-66. PubMed ID: 23567074
[TBL] [Abstract][Full Text] [Related]
17. Practical application of guinea pig telemetry system for QT evaluation.
Shiotani M; Harada T; Abe J; Sawada Y; Hashimoto K; Hamada Y; Horii I
J Toxicol Sci; 2005 Aug; 30(3):239-47. PubMed ID: 16141657
[TBL] [Abstract][Full Text] [Related]
18. Cardiovascular monkey telemetry: sensitivity to detect QT interval prolongation.
Chaves AA; Keller WJ; O'Sullivan S; Williams MA; Fitzgerald LE; McPherson HE; Goykhman D; Ward PD; Hoe CM; Mixson L; Briscoe RJ
J Pharmacol Toxicol Methods; 2006; 54(2):150-8. PubMed ID: 16679034
[TBL] [Abstract][Full Text] [Related]
19. Interferences of the autonomic nervous system with drug induced QT prolongation: a point to consider in non-clinical safety studies.
Champeroux P; Ouillé A; Martel E; Fowler JS; Maurin A; Jude S; Lala P; Le Guennec JY; Richard S
J Pharmacol Toxicol Methods; 2010; 61(3):251-63. PubMed ID: 20172034
[TBL] [Abstract][Full Text] [Related]
20. A method for QT correction based on beat-to-beat analysis of the QT/RR interval relationship in conscious telemetred beagle dogs.
Batey AJ; Doe CP
J Pharmacol Toxicol Methods; 2002; 48(1):11-9. PubMed ID: 12750037
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
