BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

680 related articles for article (PubMed ID: 16584116)

  • 1. Cytochrome P450s and other enzymes in drug metabolism and toxicity.
    Guengerich FP
    AAPS J; 2006 Mar; 8(1):E101-11. PubMed ID: 16584116
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differences in Toxicological and Pharmacological Responses Mediated by Polymorphic Cytochromes P450 and Related Drug-Metabolizing Enzymes.
    Yamazaki H
    Chem Res Toxicol; 2017 Jan; 30(1):53-60. PubMed ID: 27750412
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Non-cytochrome P450-mediated bioactivation and its toxicological relevance.
    Gan J; Ma S; Zhang D
    Drug Metab Rev; 2016 Nov; 48(4):473-501. PubMed ID: 27533622
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Chemical toxicology: reactive intermediates and their role in pharmacology and toxicology.
    Erve JC
    Expert Opin Drug Metab Toxicol; 2006 Dec; 2(6):923-46. PubMed ID: 17125409
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cytochrome P450s: mechanisms and biological implications in drug metabolism and its interaction with oxidative stress.
    Bhattacharyya S; Sinha K; Sil PC
    Curr Drug Metab; 2014; 15(7):719-42. PubMed ID: 25429675
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Detecting reactive drug metabolites for reducing the potential for drug toxicity.
    Grillo MP
    Expert Opin Drug Metab Toxicol; 2015; 11(8):1281-302. PubMed ID: 26005795
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of human hepatic cytochromes P450 in drug metabolism and toxicity.
    George J; Farrell GC
    Aust N Z J Med; 1991 Jun; 21(3):356-62. PubMed ID: 1953519
    [No Abstract]   [Full Text] [Related]  

  • 8. Catalytic selectivity of human cytochrome P450 enzymes: relevance to drug metabolism and toxicity.
    Guengerich FP
    Toxicol Lett; 1994 Feb; 70(2):133-8. PubMed ID: 8296317
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Bioactivation of drugs: risk and drug design.
    Walsh JS; Miwa GT
    Annu Rev Pharmacol Toxicol; 2011; 51():145-67. PubMed ID: 21210745
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cytochrome p450 and chemical toxicology.
    Guengerich FP
    Chem Res Toxicol; 2008 Jan; 21(1):70-83. PubMed ID: 18052394
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Streptomyces cytochromes P450: applications in drug metabolism.
    Lamb DC; Waterman MR; Zhao B
    Expert Opin Drug Metab Toxicol; 2013 Oct; 9(10):1279-94. PubMed ID: 23738914
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Intersection of the Roles of Cytochrome P450 Enzymes with Xenobiotic and Endogenous Substrates: Relevance to Toxicity and Drug Interactions.
    Guengerich FP
    Chem Res Toxicol; 2017 Jan; 30(1):2-12. PubMed ID: 27472660
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [From the Viewpoint of Drug Metabolism Research].
    Nakajima M
    Yakugaku Zasshi; 2017; 137(6):697-705. PubMed ID: 28566576
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Drug bioactivation, covalent binding to target proteins and toxicity relevance.
    Zhou S; Chan E; Duan W; Huang M; Chen YZ
    Drug Metab Rev; 2005; 37(1):41-213. PubMed ID: 15747500
    [TBL] [Abstract][Full Text] [Related]  

  • 15. [Cytochrome p450 and their implication in chemotherapy].
    Delwaide PA
    Rev Med Liege; 1998 Nov; 53(11):700-10. PubMed ID: 9887664
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Idiosyncratic drug reactions. Metabolic bioactivation as a pathogenic mechanism.
    Pirmohamed M; Madden S; Park BK
    Clin Pharmacokinet; 1996 Sep; 31(3):215-30. PubMed ID: 8877251
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Sakatis MZ; Reese MJ; Harrell AW; Taylor MA; Baines IA; Chen L; Bloomer JC; Yang EY; Ellens HM; Ambroso JL; Lovatt CA; Ayrton AD; Clarke SE
    Chem Res Toxicol; 2012 Oct; 25(10):2067-82. PubMed ID: 22931300
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cytochrome p450 part 2: what nurses need to know about the cytochrome p450 family systems.
    Krau SD
    Nurs Clin North Am; 2013 Dec; 48(4):681-96. PubMed ID: 24295195
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The effect of cytochrome P450 metabolism on drug response, interactions, and adverse effects.
    Lynch T; Price A
    Am Fam Physician; 2007 Aug; 76(3):391-6. PubMed ID: 17708140
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular modeling of cytochrome P450 and drug metabolism.
    Wang JF; Chou KC
    Curr Drug Metab; 2010 May; 11(4):342-6. PubMed ID: 20446905
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 34.