304 related articles for article (PubMed ID: 16585195)
1. The oxygen sensor factor-inhibiting hypoxia-inducible factor-1 controls expression of distinct genes through the bifunctional transcriptional character of hypoxia-inducible factor-1alpha.
Dayan F; Roux D; Brahimi-Horn MC; Pouyssegur J; Mazure NM
Cancer Res; 2006 Apr; 66(7):3688-98. PubMed ID: 16585195
[TBL] [Abstract][Full Text] [Related]
2. Hypoxia inducible factor-1 activation by prolyl 4-hydroxylase-2 gene silencing attenuates myocardial ischemia reperfusion injury.
Natarajan R; Salloum FN; Fisher BJ; Kukreja RC; Fowler AA
Circ Res; 2006 Jan; 98(1):133-40. PubMed ID: 16306444
[TBL] [Abstract][Full Text] [Related]
3. Overexpression and nuclear translocation of hypoxia-inducible factor prolyl hydroxylase PHD2 in head and neck squamous cell carcinoma is associated with tumor aggressiveness.
Jokilehto T; Rantanen K; Luukkaa M; Heikkinen P; Grenman R; Minn H; Kronqvist P; Jaakkola PM
Clin Cancer Res; 2006 Feb; 12(4):1080-7. PubMed ID: 16489060
[TBL] [Abstract][Full Text] [Related]
4. Inhibition of the catalytic activity of hypoxia-inducible factor-1alpha-prolyl-hydroxylase 2 by a MYND-type zinc finger.
Choi KO; Lee T; Lee N; Kim JH; Yang EG; Yoon JM; Kim JH; Lee TG; Park H
Mol Pharmacol; 2005 Dec; 68(6):1803-9. PubMed ID: 16155211
[TBL] [Abstract][Full Text] [Related]
5. Use of novel monoclonal antibodies to determine the expression and distribution of the hypoxia regulatory factors PHD-1, PHD-2, PHD-3 and FIH in normal and neoplastic human tissues.
Soilleux EJ; Turley H; Tian YM; Pugh CW; Gatter KC; Harris AL
Histopathology; 2005 Dec; 47(6):602-10. PubMed ID: 16324198
[TBL] [Abstract][Full Text] [Related]
6. [Effect of silencing HIF-1alpha by RNA interference on expression of vascular endothelial growth factor in osteosarcoma cell line SaOS-2 under hypoxia].
Wu Q; Yang SH; Wang RY; Ye SN; Xia T; Ma DZ
Ai Zheng; 2005 May; 24(5):531-5. PubMed ID: 15890092
[TBL] [Abstract][Full Text] [Related]
7. Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected].
Stolze IP; Tian YM; Appelhoff RJ; Turley H; Wykoff CC; Gleadle JM; Ratcliffe PJ
J Biol Chem; 2004 Oct; 279(41):42719-25. PubMed ID: 15302861
[TBL] [Abstract][Full Text] [Related]
8. Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.
Marxsen JH; Stengel P; Doege K; Heikkinen P; Jokilehto T; Wagner T; Jelkmann W; Jaakkola P; Metzen E
Biochem J; 2004 Aug; 381(Pt 3):761-7. PubMed ID: 15104534
[TBL] [Abstract][Full Text] [Related]
9. [Reciprocal regulation between hypoxia-inducible factor-1alpha and its prolyl hydroxylases in hypoxic pulmonary hypertension rats].
Chen YR; Dai AG; Hu RC
Zhonghua Jie He He Hu Xi Za Zhi; 2006 Oct; 29(10):668-73. PubMed ID: 17129494
[TBL] [Abstract][Full Text] [Related]
10. Predominant role of hypoxia-inducible transcription factor (Hif)-1alpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia.
Sowter HM; Raval RR; Moore JW; Ratcliffe PJ; Harris AL
Cancer Res; 2003 Oct; 63(19):6130-4. PubMed ID: 14559790
[TBL] [Abstract][Full Text] [Related]
11. Hypoxic preconditioning produces differential expression of hypoxia-inducible factor-1alpha (HIF-1alpha) and its regulatory enzyme HIF prolyl hydroxylase 2 in neonatal rat brain.
Jones NM; Lee EM; Brown TG; Jarrott B; Beart PM
Neurosci Lett; 2006 Aug; 404(1-2):72-7. PubMed ID: 16828226
[TBL] [Abstract][Full Text] [Related]
12. Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing.
Metzen E; Berchner-Pfannschmidt U; Stengel P; Marxsen JH; Stolze I; Klinger M; Huang WQ; Wotzlaw C; Hellwig-Bürgel T; Jelkmann W; Acker H; Fandrey J
J Cell Sci; 2003 Apr; 116(Pt 7):1319-26. PubMed ID: 12615973
[TBL] [Abstract][Full Text] [Related]
13. HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia.
Berra E; Benizri E; Ginouvès A; Volmat V; Roux D; Pouysségur J
EMBO J; 2003 Aug; 22(16):4082-90. PubMed ID: 12912907
[TBL] [Abstract][Full Text] [Related]
14. Expression of prolyl-hydroxylase-1 (PHD1/EGLN2) suppresses hypoxia inducible factor-1alpha activation and inhibits tumor growth.
Erez N; Milyavsky M; Eilam R; Shats I; Goldfinger N; Rotter V
Cancer Res; 2003 Dec; 63(24):8777-83. PubMed ID: 14695194
[TBL] [Abstract][Full Text] [Related]
15. Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases.
Koivunen P; Hirsilä M; Günzler V; Kivirikko KI; Myllyharju J
J Biol Chem; 2004 Mar; 279(11):9899-904. PubMed ID: 14701857
[TBL] [Abstract][Full Text] [Related]
16. The peptidyl prolyl cis/trans isomerase FKBP38 determines hypoxia-inducible transcription factor prolyl-4-hydroxylase PHD2 protein stability.
Barth S; Nesper J; Hasgall PA; Wirthner R; Nytko KJ; Edlich F; Katschinski DM; Stiehl DP; Wenger RH; Camenisch G
Mol Cell Biol; 2007 May; 27(10):3758-68. PubMed ID: 17353276
[TBL] [Abstract][Full Text] [Related]
17. Identification of residues critical for regulation of protein stability and the transactivation function of the hypoxia-inducible factor-1alpha by the von Hippel-Lindau tumor suppressor gene product.
Pereira T; Zheng X; Ruas JL; Tanimoto K; Poellinger L
J Biol Chem; 2003 Feb; 278(9):6816-23. PubMed ID: 12468553
[TBL] [Abstract][Full Text] [Related]
18. Mutant V600E BRAF increases hypoxia inducible factor-1alpha expression in melanoma.
Kumar SM; Yu H; Edwards R; Chen L; Kazianis S; Brafford P; Acs G; Herlyn M; Xu X
Cancer Res; 2007 Apr; 67(7):3177-84. PubMed ID: 17409425
[TBL] [Abstract][Full Text] [Related]
19. Leu-574 of human HIF-1alpha is a molecular determinant of prolyl hydroxylation.
Kageyama Y; Koshiji M; To KK; Tian YM; Ratcliffe PJ; Huang LE
FASEB J; 2004 Jun; 18(9):1028-30. PubMed ID: 15084514
[TBL] [Abstract][Full Text] [Related]
20. Coordinate regulation of the oxygen-dependent degradation domains of hypoxia-inducible factor 1 alpha.
Chan DA; Sutphin PD; Yen SE; Giaccia AJ
Mol Cell Biol; 2005 Aug; 25(15):6415-26. PubMed ID: 16024780
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
