BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

306 related articles for article (PubMed ID: 16585195)

  • 41. Chelation of cellular calcium modulates hypoxia-inducible gene expression through activation of hypoxia-inducible factor-1alpha.
    Berchner-Pfannschmidt U; Petrat F; Doege K; Trinidad B; Freitag P; Metzen E; de Groot H; Fandrey J
    J Biol Chem; 2004 Oct; 279(43):44976-86. PubMed ID: 15322093
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Functional analysis of hypoxia-inducible factor-1 alpha-mediated transactivation. Identification of amino acid residues critical for transcriptional activation and/or interaction with CREB-binding protein.
    Ruas JL; Poellinger L; Pereira T
    J Biol Chem; 2002 Oct; 277(41):38723-30. PubMed ID: 12133832
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Structure of factor-inhibiting hypoxia-inducible factor 1: An asparaginyl hydroxylase involved in the hypoxic response pathway.
    Dann CE; Bruick RK; Deisenhofer J
    Proc Natl Acad Sci U S A; 2002 Nov; 99(24):15351-6. PubMed ID: 12432100
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Selective inhibition of factor inhibiting hypoxia-inducible factor.
    McDonough MA; McNeill LA; Tilliet M; Papamicaël CA; Chen QY; Banerji B; Hewitson KS; Schofield CJ
    J Am Chem Soc; 2005 Jun; 127(21):7680-1. PubMed ID: 15913349
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Inhibition of hypoxia-inducible factor (HIF) hydroxylases by citric acid cycle intermediates: possible links between cell metabolism and stabilization of HIF.
    Koivunen P; Hirsilä M; Remes AM; Hassinen IE; Kivirikko KI; Myllyharju J
    J Biol Chem; 2007 Feb; 282(7):4524-4532. PubMed ID: 17182618
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Differential regulation of HIF-1 alpha prolyl-4-hydroxylase genes by hypoxia in human cardiovascular cells.
    Cioffi CL; Liu XQ; Kosinski PA; Garay M; Bowen BR
    Biochem Biophys Res Commun; 2003 Apr; 303(3):947-53. PubMed ID: 12670503
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Protein kinase C zeta transactivates hypoxia-inducible factor alpha by promoting its association with p300 in renal cancer.
    Datta K; Li J; Bhattacharya R; Gasparian L; Wang E; Mukhopadhyay D
    Cancer Res; 2004 Jan; 64(2):456-62. PubMed ID: 14744756
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Endogenous 2-oxoacids differentially regulate expression of oxygen sensors.
    Dalgard CL; Lu H; Mohyeldin A; Verma A
    Biochem J; 2004 Jun; 380(Pt 2):419-24. PubMed ID: 14984367
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Cell-specific regulation of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha stabilization and transactivation in a graded oxygen environment.
    Bracken CP; Fedele AO; Linke S; Balrak W; Lisy K; Whitelaw ML; Peet DJ
    J Biol Chem; 2006 Aug; 281(32):22575-85. PubMed ID: 16760477
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Induction of human endometrial cancer cell senescence through modulation of HIF-1alpha activity by EGLN1.
    Kato H; Inoue T; Asanoma K; Nishimura C; Matsuda T; Wake N
    Int J Cancer; 2006 Mar; 118(5):1144-53. PubMed ID: 16161047
    [TBL] [Abstract][Full Text] [Related]  

  • 51. BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alpha.
    Kim JY; Ahn HJ; Ryu JH; Suk K; Park JH
    J Exp Med; 2004 Jan; 199(1):113-24. PubMed ID: 14699081
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Topical prolyl hydroxylase domain-2 silencing improves diabetic murine wound closure.
    Wetterau M; George F; Weinstein A; Nguyen PD; Tutela JP; Knobel D; Cohen Ba O; Warren SM; Saadeh PB
    Wound Repair Regen; 2011; 19(4):481-6. PubMed ID: 21627711
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Mucin 1 oncoprotein blocks hypoxia-inducible factor 1alpha activation in a survival response to hypoxia.
    Yin L; Kharbanda S; Kufe D
    J Biol Chem; 2007 Jan; 282(1):257-66. PubMed ID: 17102128
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Prolyl hydroxylase inhibitor treatment confers whole-animal hypoxia tolerance.
    Kasiganesan H; Sridharan V; Wright G
    Acta Physiol (Oxf); 2007 Jun; 190(2):163-9. PubMed ID: 17394573
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Cyclosporin A prevents the hypoxic adaptation by activating hypoxia-inducible factor-1alpha Pro-564 hydroxylation.
    D'Angelo G; Duplan E; Vigne P; Frelin C
    J Biol Chem; 2003 Apr; 278(17):15406-11. PubMed ID: 12586829
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Amplification of tumor hypoxic responses by macrophage migration inhibitory factor-dependent hypoxia-inducible factor stabilization.
    Winner M; Koong AC; Rendon BE; Zundel W; Mitchell RA
    Cancer Res; 2007 Jan; 67(1):186-93. PubMed ID: 17210698
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Studies on the activity of the hypoxia-inducible-factor hydroxylases using an oxygen consumption assay.
    Ehrismann D; Flashman E; Genn DN; Mathioudakis N; Hewitson KS; Ratcliffe PJ; Schofield CJ
    Biochem J; 2007 Jan; 401(1):227-34. PubMed ID: 16952279
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways.
    Zheng X; Linke S; Dias JM; Zheng X; Gradin K; Wallis TP; Hamilton BR; Gustafsson M; Ruas JL; Wilkins S; Bilton RL; Brismar K; Whitelaw ML; Pereira T; Gorman JJ; Ericson J; Peet DJ; Lendahl U; Poellinger L
    Proc Natl Acad Sci U S A; 2008 Mar; 105(9):3368-73. PubMed ID: 18299578
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Class I and IIa HDACs Mediate HIF-1α Stability Through PHD2-Dependent Mechanism, While HDAC6, a Class IIb Member, Promotes HIF-1α Transcriptional Activity in Nucleus Pulposus Cells of the Intervertebral Disc.
    Schoepflin ZR; Shapiro IM; Risbud MV
    J Bone Miner Res; 2016 Jun; 31(6):1287-99. PubMed ID: 26765925
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Structure of human FIH-1 reveals a unique active site pocket and interaction sites for HIF-1 and von Hippel-Lindau.
    Lee C; Kim SJ; Jeong DG; Lee SM; Ryu SE
    J Biol Chem; 2003 Feb; 278(9):7558-63. PubMed ID: 12482756
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 16.