715 related articles for article (PubMed ID: 16585505)
1. Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse.
Bardeesy N; Aguirre AJ; Chu GC; Cheng KH; Lopez LV; Hezel AF; Feng B; Brennan C; Weissleder R; Mahmood U; Hanahan D; Redston MS; Chin L; Depinho RA
Proc Natl Acad Sci U S A; 2006 Apr; 103(15):5947-52. PubMed ID: 16585505
[TBL] [Abstract][Full Text] [Related]
2. Obligate roles for p16(Ink4a) and p19(Arf)-p53 in the suppression of murine pancreatic neoplasia.
Bardeesy N; Morgan J; Sinha M; Signoretti S; Srivastava S; Loda M; Merlino G; DePinho RA
Mol Cell Biol; 2002 Jan; 22(2):635-43. PubMed ID: 11756558
[TBL] [Abstract][Full Text] [Related]
3. p53 and p16
Azzopardi S; Pang S; Klimstra DS; Du YN
Neoplasia; 2016 Oct; 18(10):610-617. PubMed ID: 27664376
[TBL] [Abstract][Full Text] [Related]
4. The differential impact of p16(INK4a) or p19(ARF) deficiency on cell growth and tumorigenesis.
Sharpless NE; Ramsey MR; Balasubramanian P; Castrillon DH; DePinho RA
Oncogene; 2004 Jan; 23(2):379-85. PubMed ID: 14724566
[TBL] [Abstract][Full Text] [Related]
5. Resistance of primary cultured mouse hepatic tumor cells to cellular senescence despite expression of p16(Ink4a), p19(Arf), p53, and p21(Waf1/Cip1).
Obata M; Imamura E; Yoshida Y; Goto J; Kishibe K; Yasuda A; Ogawa K
Mol Carcinog; 2001 Sep; 32(1):9-18. PubMed ID: 11568971
[TBL] [Abstract][Full Text] [Related]
6. Genetic status of cell cycle regulators in squamous cell carcinoma of the oesophagus: the CDKN2A (p16(INK4a) and p14(ARF) ) and p53 genes are major targets for inactivation.
Smeds J; Berggren P; Ma X; Xu Z; Hemminki K; Kumar R
Carcinogenesis; 2002 Apr; 23(4):645-55. PubMed ID: 11960918
[TBL] [Abstract][Full Text] [Related]
7. Definition of three minimal deleted regions by comprehensive allelotyping and mutational screening of FHIT,p16(INK4A), and p19(ARF) genes in nasopharyngeal carcinoma.
Ko JY; Lee TC; Hsiao CF; Lin GL; Yen SH; Chen KY; Hsiung CA; Chen PJ; Hsu MM; Jou YS
Cancer; 2002 Apr; 94(7):1987-96. PubMed ID: 11932901
[TBL] [Abstract][Full Text] [Related]
8. The inhibitor of cyclin-dependent kinase 4a/alternative reading frame (INK4a/ARF) locus encoded proteins p16INK4a and p19ARF repress cyclin D1 transcription through distinct cis elements.
D'Amico M; Wu K; Fu M; Rao M; Albanese C; Russell RG; Lian H; Bregman D; White MA; Pestell RG
Cancer Res; 2004 Jun; 64(12):4122-30. PubMed ID: 15205322
[TBL] [Abstract][Full Text] [Related]
9. Inactivation of the INK4a/ARF locus and p53 in sporadic extrahepatic bile duct cancers and bile tract cancer cell lines.
Caca K; Feisthammel J; Klee K; Tannapfel A; Witzigmann H; Wittekind C; Mössner J; Berr F
Int J Cancer; 2002 Feb; 97(4):481-8. PubMed ID: 11802210
[TBL] [Abstract][Full Text] [Related]
10. Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma.
Aguirre AJ; Bardeesy N; Sinha M; Lopez L; Tuveson DA; Horner J; Redston MS; DePinho RA
Genes Dev; 2003 Dec; 17(24):3112-26. PubMed ID: 14681207
[TBL] [Abstract][Full Text] [Related]
11. p16(Ink4a) interferes with Abelson virus transformation by enhancing apoptosis.
Sachs Z; Sharpless NE; DePinho RA; Rosenberg N
J Virol; 2004 Apr; 78(7):3304-11. PubMed ID: 15016851
[TBL] [Abstract][Full Text] [Related]
12. Mice with alterations in both p53 and Ink4a/Arf display a striking increase in lung tumor multiplicity and progression: differential chemopreventive effect of budesonide in wild-type and mutant A/J mice.
Wang Y; Zhang Z; Kastens E; Lubet RA; You M
Cancer Res; 2003 Aug; 63(15):4389-95. PubMed ID: 12907609
[TBL] [Abstract][Full Text] [Related]
13. p19(Arf) induces p53-dependent apoptosis during abelson virus-mediated pre-B cell transformation.
Radfar A; Unnikrishnan I; Lee HW; DePinho RA; Rosenberg N
Proc Natl Acad Sci U S A; 1998 Oct; 95(22):13194-9. PubMed ID: 9789064
[TBL] [Abstract][Full Text] [Related]
14. The role of Ink4a/Arf in ErbB2 mammary gland tumorigenesis.
D'Amico M; Wu K; Di Vizio D; Reutens AT; Stahl M; Fu M; Albanese C; Russell RG; Muller WJ; White M; Negassa A; Lee HW; DePinho RA; Pestell RG
Cancer Res; 2003 Jun; 63(12):3395-402. PubMed ID: 12810676
[TBL] [Abstract][Full Text] [Related]
15. Consistent inactivation of p19(Arf) but not p15(Ink4b) in murine myeloid cells transformed in vivo by deregulated c-Myc.
Haviernik P; Schmidt M; Hu X; Wolff L
Oncogene; 2003 Mar; 22(11):1600-10. PubMed ID: 12642863
[TBL] [Abstract][Full Text] [Related]
16. INK4a-ARF alterations and p53 mutations in primary and consecutive squamous cell carcinoma of the head and neck.
Weber A; Bellmann U; Bootz F; Wittekind C; Tannapfel A
Virchows Arch; 2002 Aug; 441(2):133-42. PubMed ID: 12189502
[TBL] [Abstract][Full Text] [Related]
17. Genetic alterations of INK4alpha/ARF locus and p53 in human hepatocellular carcinoma.
Peng CY; Chen TC; Hung SP; Chen MF; Yeh CT; Tsai SL; Chu CM; Liaw YF
Anticancer Res; 2002; 22(2B):1265-71. PubMed ID: 12168936
[TBL] [Abstract][Full Text] [Related]
18. Losses of both products of the Cdkn2a/Arf locus contribute to asbestos-induced mesothelioma development and cooperate to accelerate tumorigenesis.
Altomare DA; Menges CW; Xu J; Pei J; Zhang L; Tadevosyan A; Neumann-Domer E; Liu Z; Carbone M; Chudoba I; Klein-Szanto AJ; Testa JR
PLoS One; 2011 Apr; 6(4):e18828. PubMed ID: 21526190
[TBL] [Abstract][Full Text] [Related]
19. Quantitative real-time PCR does not show selective targeting of p14(ARF) but concomitant inactivation of both p16(INK4A) and p14(ARF) in 105 human primary gliomas.
Labuhn M; Jones G; Speel EJ; Maier D; Zweifel C; Gratzl O; Van Meir EG; Hegi ME; Merlo A
Oncogene; 2001 Mar; 20(9):1103-9. PubMed ID: 11314047
[TBL] [Abstract][Full Text] [Related]
20. INK4a-ARF alterations and p53 mutations in hepatocellular carcinomas.
Tannapfel A; Busse C; Weinans L; Benicke M; Katalinic A; Geissler F; Hauss J; Wittekind C
Oncogene; 2001 Oct; 20(48):7104-9. PubMed ID: 11704835
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
