BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

378 related articles for article (PubMed ID: 16595712)

  • 1. Expression, purification, and characterization of mouse CYP2d22.
    Yu AM; Haining RL
    Drug Metab Dispos; 2006 Jul; 34(7):1167-74. PubMed ID: 16595712
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metabolism of dextromethorphan in vitro: involvement of cytochromes P450 2D6 and 3A3/4, with a possible role of 2E1.
    Schmider J; Greenblatt DJ; Fogelman SM; von Moltke LL; Shader RI
    Biopharm Drug Dispos; 1997 Apr; 18(3):227-40. PubMed ID: 9113345
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Influence of phenylalanine-481 substitutions on the catalytic activity of cytochrome P450 2D6.
    Hayhurst GP; Harlow J; Chowdry J; Gross E; Hilton E; Lennard MS; Tucker GT; Ellis SW
    Biochem J; 2001 Apr; 355(Pt 2):373-9. PubMed ID: 11284724
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Characterization of cytochrome P450 2D6.1 (CYP2D6.1), CYP2D6.2, and CYP2D6.17 activities toward model CYP2D6 substrates dextromethorphan, bufuralol, and debrisoquine.
    Marcucci KA; Pearce RE; Crespi C; Steimel DT; Leeder JS; Gaedigk A
    Drug Metab Dispos; 2002 May; 30(5):595-601. PubMed ID: 11950793
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes.
    Lalovic B; Phillips B; Risler LL; Howald W; Shen DD
    Drug Metab Dispos; 2004 Apr; 32(4):447-54. PubMed ID: 15039299
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Microsomal codeine N-demethylation: cosegregation with cytochrome P4503A4 activity.
    Caraco Y; Tateishi T; Guengerich FP; Wood AJ
    Drug Metab Dispos; 1996 Jul; 24(7):761-4. PubMed ID: 8818573
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The potential for CYP2D6 inhibition screening using a novel scintillation proximity assay-based approach.
    Delaporte E; Slaughter DE; Egan MA; Gatto GJ; Santos A; Shelley J; Price E; Howells L; Dean DC; Rodrigues AD
    J Biomol Screen; 2001 Aug; 6(4):225-31. PubMed ID: 11689122
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterization of dextromethorphan N-demethylation by human liver microsomes. Contribution of the cytochrome P450 3A (CYP3A) subfamily.
    Gorski JC; Jones DR; Wrighton SA; Hall SD
    Biochem Pharmacol; 1994 Jul; 48(1):173-82. PubMed ID: 8043020
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of dextromethorphan O- and N-demethylation catalyzed by highly purified recombinant human CYP2D6.
    Yu A; Dong H; Lang D; Haining RL
    Drug Metab Dispos; 2001 Nov; 29(11):1362-5. PubMed ID: 11602510
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 2,5-Dimethoxyamphetamine-derived designer drugs: studies on the identification of cytochrome P450 (CYP) isoenzymes involved in formation of their main metabolites and on their capability to inhibit CYP2D6.
    Ewald AH; Maurer HH
    Toxicol Lett; 2008 Dec; 183(1-3):52-7. PubMed ID: 18938231
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Azelastine N-demethylation by cytochrome P-450 (CYP)3A4, CYP2D6, and CYP1A2 in human liver microsomes: evaluation of approach to predict the contribution of multiple CYPs.
    Nakajima M; Nakamura S; Tokudome S; Shimada N; Yamazaki H; Yokoi T
    Drug Metab Dispos; 1999 Dec; 27(12):1381-91. PubMed ID: 10570018
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cynomolgus monkey CYP2D44 newly identified in liver, metabolizes bufuralol, and dextromethorphan.
    Uno Y; Uehara S; Kohara S; Murayama N; Yamazaki H
    Drug Metab Dispos; 2010 Sep; 38(9):1486-92. PubMed ID: 20501912
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The effect of cimetidine on dextromethorphan O-demethylase activity of human liver microsomes and recombinant CYP2D6.
    Madeira M; Levine M; Chang TK; Mirfazaelian A; Bellward GD
    Drug Metab Dispos; 2004 Apr; 32(4):460-7. PubMed ID: 16680870
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Comparative metabolic capabilities and inhibitory profiles of CYP2D6.1, CYP2D6.10, and CYP2D6.17.
    Shen H; He MM; Liu H; Wrighton SA; Wang L; Guo B; Li C
    Drug Metab Dispos; 2007 Aug; 35(8):1292-300. PubMed ID: 17470523
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Different effects of inhibitors on the O- and N-demethylation of codeine in human liver microsomes.
    Yue QY; Säwe J
    Eur J Clin Pharmacol; 1997; 52(1):41-7. PubMed ID: 9143866
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Expression, purification, biochemical characterization, and comparative function of human cytochrome P450 2D6.1, 2D6.2, 2D6.10, and 2D6.17 allelic isoforms.
    Yu A; Kneller BM; Rettie AE; Haining RL
    J Pharmacol Exp Ther; 2002 Dec; 303(3):1291-300. PubMed ID: 12438554
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The role of CYP2D6 in primary and secondary oxidative metabolism of dextromethorphan: in vitro studies using human liver microsomes.
    Kerry NL; Somogyi AA; Bochner F; Mikus G
    Br J Clin Pharmacol; 1994 Sep; 38(3):243-8. PubMed ID: 7826826
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of the cytochrome P450 isoenzymes involved in the in vitro N-dealkylation of haloperidol.
    Pan LP; Wijnant P; De Vriendt C; Rosseel MT; Belpaire FM
    Br J Clin Pharmacol; 1997 Dec; 44(6):557-64. PubMed ID: 9431831
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization of the human cytochrome P450 enzymes involved in the metabolism of dihydrocodeine.
    Kirkwood LC; Nation RL; Somogyi AA
    Br J Clin Pharmacol; 1997 Dec; 44(6):549-55. PubMed ID: 9431830
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Comparative contribution to dextromethorphan metabolism by cytochrome P450 isoforms in vitro: can dextromethorphan be used as a dual probe for both CTP2D6 and CYP3A activities?
    Yu A; Haining RL
    Drug Metab Dispos; 2001 Nov; 29(11):1514-20. PubMed ID: 11602530
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.