BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

136 related articles for article (PubMed ID: 16597547)

  • 1. Gene expression analysis of troglitazone reveals its impact on multiple pathways in cell culture: a case for in vitro platforms combined with gene expression analysis for early (idiosyncratic) toxicity screening.
    Vansant G; Pezzoli P; Saiz R; Birch A; Duffy C; Ferre F; Monforte J
    Int J Toxicol; 2006; 25(2):85-94. PubMed ID: 16597547
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Species-specific toxicity of diclofenac and troglitazone in primary human and rat hepatocytes.
    Lauer B; Tuschl G; Kling M; Mueller SO
    Chem Biol Interact; 2009 Apr; 179(1):17-24. PubMed ID: 19022234
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Differences in hepatotoxicity and gene expression profiles by anti-diabetic PPAR gamma agonists on rat primary hepatocytes and human HepG2 cells.
    Guo L; Zhang L; Sun Y; Muskhelishvili L; Blann E; Dial S; Shi L; Schroth G; Dragan YP
    Mol Divers; 2006 Aug; 10(3):349-60. PubMed ID: 17031537
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Increased sensitivity for troglitazone-induced cytotoxicity using a human in vitro co-culture model.
    Edling Y; Sivertsson LK; Butura A; Ingelman-Sundberg M; Ek M
    Toxicol In Vitro; 2009 Oct; 23(7):1387-95. PubMed ID: 19631733
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Comparative gene expression profiles induced by PPARγ and PPARα/γ agonists in rat hepatocytes.
    Rogue A; Renaud MP; Claude N; Guillouzo A; Spire C
    Toxicol Appl Pharmacol; 2011 Jul; 254(1):18-31. PubMed ID: 21515302
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Species-specific toxicity of troglitazone on rats and human by gel entrapped hepatocytes.
    Shen C; Meng Q; Zhang G
    Toxicol Appl Pharmacol; 2012 Jan; 258(1):19-25. PubMed ID: 22085495
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Thiazolidinedione bioactivation: a comparison of the bioactivation potentials of troglitazone, rosiglitazone, and pioglitazone using stable isotope-labeled analogues and liquid chromatography tandem mass spectrometry.
    Alvarez-Sanchez R; Montavon F; Hartung T; Pähler A
    Chem Res Toxicol; 2006 Aug; 19(8):1106-16. PubMed ID: 16918252
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The mitochondrial superoxide/thioredoxin-2/Ask1 signaling pathway is critically involved in troglitazone-induced cell injury to human hepatocytes.
    Lim PL; Liu J; Go ML; Boelsterli UA
    Toxicol Sci; 2008 Feb; 101(2):341-9. PubMed ID: 17975114
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Direct toxicity effects of sulfo-conjugated troglitazone on human hepatocytes.
    Saha S; New LS; Ho HK; Chui WK; Chan EC
    Toxicol Lett; 2010 Jun; 195(2-3):135-41. PubMed ID: 20307632
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Carcinogenic susceptibility of rasH2 mice to troglitazone.
    Jin M; Takahashi M; Moto M; Muguruma M; Ito K; Watanabe K; Kenmochi Y; Kono T; Hasumi K; Mitsumori K
    Arch Toxicol; 2007 Dec; 81(12):883-94. PubMed ID: 17569031
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Troglitazone inhibits synthesis of transforming growth factor-beta1 and reduces matrix production in human peritoneal mesothelial cells.
    Peng Y; Liu H; Liu F; Liu Y; Li J; Chen X
    Nephrology (Carlton); 2006 Dec; 11(6):516-23. PubMed ID: 17199790
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Gene expression regulated by pioglitazone and exenatide in normal and diabetic rat islets exposed to lipotoxicity.
    Ghanaat-Pour H; Sjöholm A
    Diabetes Metab Res Rev; 2009 Feb; 25(2):163-84. PubMed ID: 19065603
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Keratinocyte-derived vascular endothelial growth factor biosynthesis represents a pleiotropic side effect of peroxisome proliferator-activated receptor-gamma agonist troglitazone but not rosiglitazone and involves activation of p38 mitogen-activated protein kinase: implications for diabetes-impaired skin repair.
    Schiefelbein D; Seitz O; Goren I; Dissmann JP; Schmidt H; Bachmann M; Sader R; Geisslinger G; Pfeilschifter J; Frank S
    Mol Pharmacol; 2008 Oct; 74(4):952-63. PubMed ID: 18599600
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A novel selective peroxisome proliferator-activator receptor-gamma modulator-SPPARgammaM5 improves insulin sensitivity with diminished adverse cardiovascular effects.
    Chang CH; McNamara LA; Wu MS; Muise ES; Tan Y; Wood HB; Meinke PT; Thompson JR; Doebber TW; Berger JP; McCann ME
    Eur J Pharmacol; 2008 Apr; 584(1):192-201. PubMed ID: 18346728
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effect of troglitazone on CYP1A1 induction.
    Kim HG; Han EH; Jeong HG
    Toxicology; 2008 Apr; 246(2-3):166-71. PubMed ID: 18308446
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Rosiglitazone increases PPARgamma in renal tubular epithelial cells and protects against damage by hydrogen peroxide.
    Sommer M; Wolf G
    Am J Nephrol; 2007; 27(4):425-34. PubMed ID: 17622750
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evaluation of direct and indirect effects of the PPARγ agonist troglitazone on mouse endothelial cell proliferation.
    Kakiuchi-Kiyota S; Arnold LL; Yokohira M; Koza-Taylor P; Suzuki S; Varney M; Pennington KL; Cohen SM
    Toxicol Pathol; 2011 Dec; 39(7):1032-45. PubMed ID: 21937740
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Investigation of the role of the thiazolidinedione ring of troglitazone in inducing hepatotoxicity.
    Saha S; New LS; Ho HK; Chui WK; Chan EC
    Toxicol Lett; 2010 Feb; 192(2):141-9. PubMed ID: 19854250
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pyrrolidinediones reduce the toxicity of thiazolidinediones and modify their anti-diabetic and anti-cancer properties.
    Saha S; Chan DS; Lee CY; Wong W; New LS; Chui WK; Yap CW; Chan EC; Ho HK
    Eur J Pharmacol; 2012 Dec; 697(1-3):13-23. PubMed ID: 23041271
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Troglitazone induces cytotoxicity in part by promoting the degradation of peroxisome proliferator-activated receptor γ co-activator-1α protein.
    Liao X; Wang Y; Wong CW
    Br J Pharmacol; 2010 Oct; 161(4):771-81. PubMed ID: 20860658
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.