173 related articles for article (PubMed ID: 16598795)
1. Combining caspase and mitochondrial dysfunction inhibitors of apoptosis to limit cell death in mammalian cell cultures.
Sauerwald TM; Figueroa B; Hardwick JM; Oyler GA; Betenbaugh MJ
Biotechnol Bioeng; 2006 Jun; 94(2):362-72. PubMed ID: 16598795
[TBL] [Abstract][Full Text] [Related]
2. Inhibiting apoptosis in mammalian cell culture using the caspase inhibitor XIAP and deletion mutants.
Sauerwald TM; Betenbaugh MJ; Oyler GA
Biotechnol Bioeng; 2002 Mar; 77(6):704-16. PubMed ID: 11807766
[TBL] [Abstract][Full Text] [Related]
3. Study of caspase inhibitors for limiting death in mammalian cell culture.
Sauerwald TM; Oyler GA; Betenbaugh MJ
Biotechnol Bioeng; 2003 Feb; 81(3):329-40. PubMed ID: 12474256
[TBL] [Abstract][Full Text] [Related]
4. Aven and Bcl-xL enhance protection against apoptosis for mammalian cells exposed to various culture conditions.
Figueroa B; Chen S; Oyler GA; Hardwick JM; Betenbaugh MJ
Biotechnol Bioeng; 2004 Mar; 85(6):589-600. PubMed ID: 14966800
[TBL] [Abstract][Full Text] [Related]
5. Combining high-throughput screening of caspase activity with anti-apoptosis genes for development of robust CHO production cell lines.
Dorai H; Ellis D; Keung YS; Campbell M; Zhuang M; Lin C; Betenbaugh MJ
Biotechnol Prog; 2010; 26(5):1367-81. PubMed ID: 20945491
[TBL] [Abstract][Full Text] [Related]
6. A comparison of the properties of a Bcl-xL variant to the wild-type anti-apoptosis inhibitor in mammalian cell cultures.
Figueroa B; Sauerwald TM; Oyler GA; Hardwick JM; Betenbaugh MJ
Metab Eng; 2003 Oct; 5(4):230-45. PubMed ID: 14642351
[TBL] [Abstract][Full Text] [Related]
7. Expression of anti-apoptosis genes alters lactate metabolism of Chinese Hamster Ovary cells in culture.
Dorai H; Kyung YS; Ellis D; Kinney C; Lin C; Jan D; Moore G; Betenbaugh MJ
Biotechnol Bioeng; 2009 Jun; 103(3):592-608. PubMed ID: 19241388
[TBL] [Abstract][Full Text] [Related]
8. Upstream regulatory role for XIAP in receptor-mediated apoptosis.
Wilkinson JC; Cepero E; Boise LH; Duckett CS
Mol Cell Biol; 2004 Aug; 24(16):7003-14. PubMed ID: 15282301
[TBL] [Abstract][Full Text] [Related]
9. Cellular, biochemical, and genetic analysis of mechanism of small molecule IAP inhibitors.
Wang Z; Cuddy M; Samuel T; Welsh K; Schimmer A; Hanaii F; Houghten R; Pinilla C; Reed JC
J Biol Chem; 2004 Nov; 279(46):48168-76. PubMed ID: 15337764
[TBL] [Abstract][Full Text] [Related]
10. Part I. Bcl-2 and Bcl-x(L) limit apoptosis upon infection with alphavirus vectors.
Mastrangelo AJ; Hardwick JM; Bex F; Betenbaugh MJ
Biotechnol Bioeng; 2000 Mar; 67(5):544-54. PubMed ID: 10649229
[TBL] [Abstract][Full Text] [Related]
11. Enhanced cell culture performance using inducible anti-apoptotic genes E1B-19K and Aven in the production of a monoclonal antibody with Chinese hamster ovary cells.
Figueroa B; Ailor E; Osborne D; Hardwick JM; Reff M; Betenbaugh MJ
Biotechnol Bioeng; 2007 Jul; 97(4):877-92. PubMed ID: 17099908
[TBL] [Abstract][Full Text] [Related]
12. Directed evolution of mammalian anti-apoptosis proteins by somatic hypermutation.
Majors BS; Chiang GG; Pederson NE; Betenbaugh MJ
Protein Eng Des Sel; 2012 Jan; 25(1):27-38. PubMed ID: 22160868
[TBL] [Abstract][Full Text] [Related]
13. Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP.
Silke J; Ekert PG; Day CL; Hawkins CJ; Baca M; Chew J; Pakusch M; Verhagen AM; Vaux DL
EMBO J; 2001 Jun; 20(12):3114-23. PubMed ID: 11406588
[TBL] [Abstract][Full Text] [Related]
14. Enhancement of transient gene expression and culture viability using Chinese hamster ovary cells overexpressing Bcl-x(L).
Majors BS; Betenbaugh MJ; Pederson NE; Chiang GG
Biotechnol Bioeng; 2008 Oct; 101(3):567-78. PubMed ID: 18727128
[TBL] [Abstract][Full Text] [Related]
15. Anti-apoptotic genes Aven and E1B-19K enhance performance of BHK cells engineered to express recombinant factor VIII in batch and low perfusion cell culture.
Nivitchanyong T; Martinez A; Ishaque A; Murphy JE; Konstantinov K; Betenbaugh MJ; Thrift J
Biotechnol Bioeng; 2007 Nov; 98(4):825-41. PubMed ID: 17514750
[TBL] [Abstract][Full Text] [Related]
16. Increased expression of the integral membrane proteins EGFR and FGFR3 in anti-apoptotic Chinese hamster ovary cell lines.
Ohsfeldt E; Huang SH; Baycin-Hizal D; Kristoffersen L; Le TM; Li E; Hristova K; Betenbaugh MJ
Biotechnol Appl Biochem; 2012; 59(3):155-62. PubMed ID: 23586824
[TBL] [Abstract][Full Text] [Related]
17. Part II. Overexpression of bcl-2 family members enhances survival of mammalian cells in response to various culture insults.
Mastrangelo AJ; Hardwick JM; Zou S; Betenbaugh MJ
Biotechnol Bioeng; 2000 Mar; 67(5):555-64. PubMed ID: 10649230
[TBL] [Abstract][Full Text] [Related]
18. Over-expression of the X-linked inhibitor of apoptosis protein (XIAP) delays serum deprivation-induced apoptosis in CHO-K1 cells.
Liew JC; Tan WS; Alitheen NB; Chan ES; Tey BT
J Biosci Bioeng; 2010 Sep; 110(3):338-44. PubMed ID: 20547346
[TBL] [Abstract][Full Text] [Related]
19. The human anti-apoptotic proteins cIAP1 and cIAP2 bind but do not inhibit caspases.
Eckelman BP; Salvesen GS
J Biol Chem; 2006 Feb; 281(6):3254-60. PubMed ID: 16339151
[TBL] [Abstract][Full Text] [Related]
20. Differential activation of apoptosis regulatory pathways during monocytic vs granulocytic differentiation: a requirement for Bcl-X(L)and XIAP in the prolonged survival of monocytic cells.
Miranda MB; Dyer KF; Grandis JR; Johnson DE
Leukemia; 2003 Feb; 17(2):390-400. PubMed ID: 12592339
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
