511 related articles for article (PubMed ID: 16601701)
1. ATM and ATR promote Mre11 dependent restart of collapsed replication forks and prevent accumulation of DNA breaks.
Trenz K; Smith E; Smith S; Costanzo V
EMBO J; 2006 Apr; 25(8):1764-74. PubMed ID: 16601701
[TBL] [Abstract][Full Text] [Related]
2. Defective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks.
Takemura H; Rao VA; Sordet O; Furuta T; Miao ZH; Meng L; Zhang H; Pommier Y
J Biol Chem; 2006 Oct; 281(41):30814-23. PubMed ID: 16905549
[TBL] [Abstract][Full Text] [Related]
3. The Mre11-Rad50-Nbs1 complex mediates activation of TopBP1 by ATM.
Yoo HY; Kumagai A; Shevchenko A; Shevchenko A; Dunphy WG
Mol Biol Cell; 2009 May; 20(9):2351-60. PubMed ID: 19279141
[TBL] [Abstract][Full Text] [Related]
4. ATM and the Mre11-Rad50-Nbs1 complex respond to nucleoside analogue-induced stalled replication forks and contribute to drug resistance.
Ewald B; Sampath D; Plunkett W
Cancer Res; 2008 Oct; 68(19):7947-55. PubMed ID: 18829552
[TBL] [Abstract][Full Text] [Related]
5. CtIP interacts with TopBP1 and Nbs1 in the response to double-stranded DNA breaks (DSBs) in Xenopus egg extracts.
RamÃrez-Lugo JS; Yoo HY; Yoon SJ; Dunphy WG
Cell Cycle; 2011 Feb; 10(3):469-80. PubMed ID: 21263215
[TBL] [Abstract][Full Text] [Related]
6. Resection of DNA double-strand breaks activates Mre11-Rad50-Nbs1- and Rad9-Hus1-Rad1-dependent mechanisms that redundantly promote ATR checkpoint activation and end processing in Xenopus egg extracts.
Tatsukawa K; Sakamoto R; Kawasoe Y; Kubota Y; Tsurimoto T; Takahashi TS; Ohashi E
Nucleic Acids Res; 2024 Apr; 52(6):3146-3163. PubMed ID: 38349040
[TBL] [Abstract][Full Text] [Related]
7. The Mre11-Rad50-Nbs1 (MRN) complex has a specific role in the activation of Chk1 in response to stalled replication forks.
Lee J; Dunphy WG
Mol Biol Cell; 2013 May; 24(9):1343-53. PubMed ID: 23468519
[TBL] [Abstract][Full Text] [Related]
8. Ataxia-telangiectasia mutated (ATM)-dependent activation of ATR occurs through phosphorylation of TopBP1 by ATM.
Yoo HY; Kumagai A; Shevchenko A; Shevchenko A; Dunphy WG
J Biol Chem; 2007 Jun; 282(24):17501-6. PubMed ID: 17446169
[TBL] [Abstract][Full Text] [Related]
9. Two-step activation of ATM by DNA and the Mre11-Rad50-Nbs1 complex.
Dupré A; Boyer-Chatenet L; Gautier J
Nat Struct Mol Biol; 2006 May; 13(5):451-7. PubMed ID: 16622404
[TBL] [Abstract][Full Text] [Related]
10. ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks.
Lavin MF
Oncogene; 2007 Dec; 26(56):7749-58. PubMed ID: 18066087
[TBL] [Abstract][Full Text] [Related]
11. Protein phosphatase 2A antagonizes ATM and ATR in a Cdk2- and Cdc7-independent DNA damage checkpoint.
Petersen P; Chou DM; You Z; Hunter T; Walter JC; Walter G
Mol Cell Biol; 2006 Mar; 26(5):1997-2011. PubMed ID: 16479016
[TBL] [Abstract][Full Text] [Related]
12. Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity.
Jazayeri A; Balestrini A; Garner E; Haber JE; Costanzo V
EMBO J; 2008 Jul; 27(14):1953-62. PubMed ID: 18596698
[TBL] [Abstract][Full Text] [Related]
13. Mcm2 is a direct substrate of ATM and ATR during DNA damage and DNA replication checkpoint responses.
Yoo HY; Shevchenko A; Shevchenko A; Dunphy WG
J Biol Chem; 2004 Dec; 279(51):53353-64. PubMed ID: 15448142
[TBL] [Abstract][Full Text] [Related]
14. A role for the MRN complex in ATR activation via TOPBP1 recruitment.
Duursma AM; Driscoll R; Elias JE; Cimprich KA
Mol Cell; 2013 Apr; 50(1):116-22. PubMed ID: 23582259
[TBL] [Abstract][Full Text] [Related]
15. Ataxia telangiectasia-mutated (ATM) kinase activity is regulated by ATP-driven conformational changes in the Mre11/Rad50/Nbs1 (MRN) complex.
Lee JH; Mand MR; Deshpande RA; Kinoshita E; Yang SH; Wyman C; Paull TT
J Biol Chem; 2013 May; 288(18):12840-51. PubMed ID: 23525106
[TBL] [Abstract][Full Text] [Related]
16. A mutant allele of MRE11 found in mismatch repair-deficient tumor cells suppresses the cellular response to DNA replication fork stress in a dominant negative manner.
Wen Q; Scorah J; Phear G; Rodgers G; Rodgers S; Meuth M
Mol Biol Cell; 2008 Apr; 19(4):1693-705. PubMed ID: 18256278
[TBL] [Abstract][Full Text] [Related]
17. Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair.
Limbo O; Moiani D; Kertokalio A; Wyman C; Tainer JA; Russell P
Nucleic Acids Res; 2012 Dec; 40(22):11435-49. PubMed ID: 23080121
[TBL] [Abstract][Full Text] [Related]
18. The Mre11 complex is required for ATM activation and the G2/M checkpoint.
Carson CT; Schwartz RA; Stracker TH; Lilley CE; Lee DV; Weitzman MD
EMBO J; 2003 Dec; 22(24):6610-20. PubMed ID: 14657032
[TBL] [Abstract][Full Text] [Related]
19. The role of NBS1 in the modulation of PIKK family proteins ATM and ATR in the cellular response to DNA damage.
Zhou J; Lim CU; Li JJ; Cai L; Zhang Y
Cancer Lett; 2006 Nov; 243(1):9-15. PubMed ID: 16530324
[TBL] [Abstract][Full Text] [Related]
20. The Mre11/Rad50/Nbs1 complex and its role as a DNA double-strand break sensor for ATM.
Paull TT; Lee JH
Cell Cycle; 2005 Jun; 4(6):737-40. PubMed ID: 15908798
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
