256 related articles for article (PubMed ID: 16604207)
1. Microtiter plate based chemistry and in situ screening: a useful approach for rapid inhibitor discovery.
Brik A; Wu CY; Wong CH
Org Biomol Chem; 2006 Apr; 4(8):1446-57. PubMed ID: 16604207
[TBL] [Abstract][Full Text] [Related]
2. Epoxide opening in water and screening in situ for rapid discovery of enzyme inhibitors in microtiter plates.
Liang FS; Brik A; Lin YC; Elder JH; Wong CH
Bioorg Med Chem; 2006 Feb; 14(4):1058-62. PubMed ID: 16275107
[TBL] [Abstract][Full Text] [Related]
3. Rapid discovery of potent sulfotransferase inhibitors by diversity-oriented reaction in microplates followed by in situ screening.
Best MD; Brik A; Chapman E; Lee LV; Cheng WC; Wong CH
Chembiochem; 2004 Jun; 5(6):811-9. PubMed ID: 15174164
[TBL] [Abstract][Full Text] [Related]
4. Rapid discovery of triazolobenzylidene-thiazolopyrimidines (TBTP) as CDC25 phosphatase inhibitors by parallel click chemistry and in situ screening.
Duval R; Kolb S; Braud E; Genest D; Garbay C
J Comb Chem; 2009; 11(6):947-50. PubMed ID: 19835352
[No Abstract] [Full Text] [Related]
5. "Inject-mix-react-separate-and-quantitate" (IMReSQ) method for screening enzyme inhibitors.
Wong E; Okhonin V; Berezovski MV; Nozaki T; Waldmann H; Alexandrov K; Krylov SN
J Am Chem Soc; 2008 Sep; 130(36):11862-3. PubMed ID: 18702487
[TBL] [Abstract][Full Text] [Related]
6. Slow-binding human serine racemase inhibitors from high-throughput screening of combinatorial libraries.
Dixon SM; Li P; Liu R; Wolosker H; Lam KS; Kurth MJ; Toney MD
J Med Chem; 2006 Apr; 49(8):2388-97. PubMed ID: 16610782
[TBL] [Abstract][Full Text] [Related]
7. Combinatorial approach toward synthesis of small molecule libraries as bacterial transglycosylase inhibitors.
Shih HW; Chen KT; Chen SK; Huang CY; Cheng TJ; Ma C; Wong CH; Cheng WC
Org Biomol Chem; 2010 Jun; 8(11):2586-93. PubMed ID: 20485795
[TBL] [Abstract][Full Text] [Related]
8. High-throughput synthesis of azide libraries suitable for direct "click" chemistry and in situ screening.
Srinivasan R; Tan LP; Wu H; Yang PY; Kalesh KA; Yao SQ
Org Biomol Chem; 2009 May; 7(9):1821-8. PubMed ID: 19590777
[TBL] [Abstract][Full Text] [Related]
9. Inhibitors of FabI, an enzyme drug target in the bacterial fatty acid biosynthesis pathway.
Lu H; Tonge PJ
Acc Chem Res; 2008 Jan; 41(1):11-20. PubMed ID: 18193820
[TBL] [Abstract][Full Text] [Related]
10. Rapid diversity-oriented synthesis in microtiter plates for in situ screening of HIV protease inhibitors.
Brik A; Muldoon J; Lin YC; Elder JH; Goodsell DS; Olson AJ; Fokin VV; Sharpless KB; Wong CH
Chembiochem; 2003 Nov; 4(11):1246-8. PubMed ID: 14613121
[No Abstract] [Full Text] [Related]
11. High-throughput characterization and quality control of small-molecule combinatorial libraries.
Kenseth JR; Coldiron SJ
Curr Opin Chem Biol; 2004 Aug; 8(4):418-23. PubMed ID: 15288253
[TBL] [Abstract][Full Text] [Related]
12. Discovery of glutathione S-transferase inhibitors using dynamic combinatorial chemistry.
Shi B; Stevenson R; Campopiano DJ; Greaney MF
J Am Chem Soc; 2006 Jul; 128(26):8459-67. PubMed ID: 16802811
[TBL] [Abstract][Full Text] [Related]
13. Discovery of an Aurora kinase inhibitor through site-specific dynamic combinatorial chemistry.
Cancilla MT; He MM; Viswanathan N; Simmons RL; Taylor M; Fung AD; Cao K; Erlanson DA
Bioorg Med Chem Lett; 2008 Jul; 18(14):3978-81. PubMed ID: 18579375
[TBL] [Abstract][Full Text] [Related]
14. High-throughput screening of enzyme inhibition using an inhibitor gradient generated in a microchannel.
Garcia E; Hasenbank MS; Finlayson B; Yager P
Lab Chip; 2007 Feb; 7(2):249-55. PubMed ID: 17268628
[TBL] [Abstract][Full Text] [Related]
15. High-speed synthesis of potent C2-symmetric HIV-1 protease inhibitors by in-situ aminocarbonylations.
Wannberg J; Kaiser NF; Vrang L; Samuelsson B; Larhed M; Hallberg A
J Comb Chem; 2005; 7(4):611-7. PubMed ID: 16004505
[TBL] [Abstract][Full Text] [Related]
16. Discovering novel ligands for macromolecules using X-ray crystallographic screening.
Nienaber VL; Richardson PL; Klighofer V; Bouska JJ; Giranda VL; Greer J
Nat Biotechnol; 2000 Oct; 18(10):1105-8. PubMed ID: 11017052
[TBL] [Abstract][Full Text] [Related]
17. Expedient solid-phase synthesis of both symmetric and asymmetric diol libraries targeting aspartic proteases.
Shi H; Liu K; Leong WW; Yao SQ
Bioorg Med Chem Lett; 2009 Jul; 19(14):3945-8. PubMed ID: 19328682
[TBL] [Abstract][Full Text] [Related]
18. Rapid diversity-oriented synthesis in microtiter plates for in situ screening: discovery of potent and selective alpha-fucosidase inhibitors.
Wu CY; Chang CF; Chen JS; Wong CH; Lin CH
Angew Chem Int Ed Engl; 2003 Oct; 42(38):4661-4. PubMed ID: 14533157
[No Abstract] [Full Text] [Related]
19. Structure-based virtual screening approach to identify novel classes of Cdc25B phosphatase inhibitors.
Park H; Li M; Choi J; Cho H; Ham SW
Bioorg Med Chem Lett; 2009 Aug; 19(15):4372-5. PubMed ID: 19500977
[TBL] [Abstract][Full Text] [Related]
20. Discovery and combinatorial synthesis of fungal metabolites beauveriolides, novel antiatherosclerotic agents.
Tomoda H; Doi T
Acc Chem Res; 2008 Jan; 41(1):32-9. PubMed ID: 17803269
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]