214 related articles for article (PubMed ID: 16605249)
1. Structural perturbations in the Ala --> Val polymorphism of methylenetetrahydrofolate reductase: how binding of folates may protect against inactivation.
Pejchal R; Campbell E; Guenther BD; Lennon BW; Matthews RG; Ludwig ML
Biochemistry; 2006 Apr; 45(15):4808-18. PubMed ID: 16605249
[TBL] [Abstract][Full Text] [Related]
2. The structure and properties of methylenetetrahydrofolate reductase from Escherichia coli suggest how folate ameliorates human hyperhomocysteinemia.
Guenther BD; Sheppard CA; Tran P; Rozen R; Matthews RG; Ludwig ML
Nat Struct Biol; 1999 Apr; 6(4):359-65. PubMed ID: 10201405
[TBL] [Abstract][Full Text] [Related]
3. Insights on the structural perturbations in human MTHFR Ala222Val mutant by protein modeling and molecular dynamics.
Abhinand PA; Shaikh F; Bhakat S; Radadiya A; Bhaskar LV; Shah A; Ragunath PK
J Biomol Struct Dyn; 2016; 34(4):892-905. PubMed ID: 26273990
[TBL] [Abstract][Full Text] [Related]
4. Structures of NADH and CH3-H4folate complexes of Escherichia coli methylenetetrahydrofolate reductase reveal a spartan strategy for a ping-pong reaction.
Pejchal R; Sargeant R; Ludwig ML
Biochemistry; 2005 Aug; 44(34):11447-57. PubMed ID: 16114881
[TBL] [Abstract][Full Text] [Related]
5. Properties and crystal structure of methylenetetrahydrofolate reductase from Thermus thermophilus HB8.
Igari S; Ohtaki A; Yamanaka Y; Sato Y; Yohda M; Odaka M; Noguchi K; Yamada K
PLoS One; 2011; 6(8):e23716. PubMed ID: 21858212
[TBL] [Abstract][Full Text] [Related]
6. Effects of common polymorphisms on the properties of recombinant human methylenetetrahydrofolate reductase.
Yamada K; Chen Z; Rozen R; Matthews RG
Proc Natl Acad Sci U S A; 2001 Dec; 98(26):14853-8. PubMed ID: 11742092
[TBL] [Abstract][Full Text] [Related]
7. Aspartate 120 of Escherichia coli methylenetetrahydrofolate reductase: evidence for major roles in folate binding and catalysis and a minor role in flavin reactivity.
Trimmer EE; Ballou DP; Galloway LJ; Scannell SA; Brinker DR; Casas KR
Biochemistry; 2005 May; 44(18):6809-22. PubMed ID: 15865426
[TBL] [Abstract][Full Text] [Related]
8. Crystal structure of Escherichia coli thioredoxin reductase refined at 2 A resolution. Implications for a large conformational change during catalysis.
Waksman G; Krishna TS; Williams CH; Kuriyan J
J Mol Biol; 1994 Feb; 236(3):800-16. PubMed ID: 8114095
[TBL] [Abstract][Full Text] [Related]
9. Functional role for the conformationally mobile phenylalanine 223 in the reaction of methylenetetrahydrofolate reductase from Escherichia coli.
Lee MN; Takawira D; Nikolova AP; Ballou DP; Furtado VC; Phung NL; Still BR; Thorstad MK; Tanner JJ; Trimmer EE
Biochemistry; 2009 Aug; 48(32):7673-85. PubMed ID: 19610625
[TBL] [Abstract][Full Text] [Related]
10. Unique holoenzyme dimers of the tetrameric enzyme Escherichia coli methylenetetrahydrofolate reductase: characterization of structural features associated with modulation of the enzyme's function.
Misra SK; Bhakuni V
Biochemistry; 2003 Apr; 42(13):3921-8. PubMed ID: 12667083
[TBL] [Abstract][Full Text] [Related]
11. Crystal structure of the flavin reductase component (HpaC) of 4-hydroxyphenylacetate 3-monooxygenase from Thermus thermophilus HB8: Structural basis for the flavin affinity.
Kim SH; Hisano T; Iwasaki W; Ebihara A; Miki K
Proteins; 2008 Feb; 70(3):718-30. PubMed ID: 17729270
[TBL] [Abstract][Full Text] [Related]
12. Characterization of a bifunctional PutA homologue from Bradyrhizobium japonicum and identification of an active site residue that modulates proline reduction of the flavin adenine dinucleotide cofactor.
Krishnan N; Becker DF
Biochemistry; 2005 Jun; 44(25):9130-9. PubMed ID: 15966737
[TBL] [Abstract][Full Text] [Related]
13. A role for glutamine 183 in the folate oxidative half-reaction of methylenetetrahydrofolate reductase from Escherichia coli.
Zuo C; Jolly AL; Nikolova AP; Satzer DI; Cao S; Sanchez JS; Ballou DP; Trimmer EE
Arch Biochem Biophys; 2018 Mar; 642():63-74. PubMed ID: 29407039
[TBL] [Abstract][Full Text] [Related]
14. The thermolabile variant 677C-->T can further reduce activity when expressed in cis with severe mutations for human methylenetetrahydrofolate reductase.
Goyette P; Rozen R
Hum Mutat; 2000; 16(2):132-8. PubMed ID: 10923034
[TBL] [Abstract][Full Text] [Related]
15. Differential contributions of NADPH-cytochrome P450 oxidoreductase FAD binding site residues to flavin binding and catalysis.
Shen AL; Kasper CB
J Biol Chem; 2000 Dec; 275(52):41087-91. PubMed ID: 11022049
[TBL] [Abstract][Full Text] [Related]
16. Structures of the Escherichia coli PutA proline dehydrogenase domain in complex with competitive inhibitors.
Zhang M; White TA; Schuermann JP; Baban BA; Becker DF; Tanner JJ
Biochemistry; 2004 Oct; 43(39):12539-48. PubMed ID: 15449943
[TBL] [Abstract][Full Text] [Related]
17. Folate activation and catalysis in methylenetetrahydrofolate reductase from Escherichia coli: roles for aspartate 120 and glutamate 28.
Trimmer EE; Ballou DP; Ludwig ML; Matthews RG
Biochemistry; 2001 May; 40(21):6216-26. PubMed ID: 11371182
[TBL] [Abstract][Full Text] [Related]
18. Mechanism of coenzyme binding to human methionine synthase reductase revealed through the crystal structure of the FNR-like module and isothermal titration calorimetry.
Wolthers KR; Lou X; Toogood HS; Leys D; Scrutton NS
Biochemistry; 2007 Oct; 46(42):11833-44. PubMed ID: 17892308
[TBL] [Abstract][Full Text] [Related]
19. Cytochrome b5 reductase: role of the si-face residues, proline 92 and tyrosine 93, in structure and catalysis.
Marohnic CC; Crowley LJ; Davis CA; Smith ET; Barber MJ
Biochemistry; 2005 Feb; 44(7):2449-61. PubMed ID: 15709757
[TBL] [Abstract][Full Text] [Related]
20. FAD is a preferred substrate and an inhibitor of Escherichia coli general NAD(P)H:flavin oxidoreductase.
Louie TM; Yang H; Karnchanaphanurach P; Xie XS; Xun L
J Biol Chem; 2002 Oct; 277(42):39450-5. PubMed ID: 12177066
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]