356 related articles for article (PubMed ID: 16608920)
1. Ketoconazole and miconazole are antagonists of the human glucocorticoid receptor: consequences on the expression and function of the constitutive androstane receptor and the pregnane X receptor.
Duret C; Daujat-Chavanieu M; Pascussi JM; Pichard-Garcia L; Balaguer P; Fabre JM; Vilarem MJ; Maurel P; Gerbal-Chaloin S
Mol Pharmacol; 2006 Jul; 70(1):329-39. PubMed ID: 16608920
[TBL] [Abstract][Full Text] [Related]
2. Expression and transcriptional activities of nuclear receptors involved in regulation of drug-metabolizing enzymes are not altered by colchicine: focus on PXR, CAR, and GR in primary human hepatocytes.
Dvorák Z; Maurel P; Vilarem MJ; Ulrichová J; Modrianský M
Cell Biol Toxicol; 2007 Mar; 23(2):63-73. PubMed ID: 16964586
[TBL] [Abstract][Full Text] [Related]
3. Transcriptional regulation of human UGT1A1 gene expression: activated glucocorticoid receptor enhances constitutive androstane receptor/pregnane X receptor-mediated UDP-glucuronosyltransferase 1A1 regulation with glucocorticoid receptor-interacting protein 1.
Sugatani J; Nishitani S; Yamakawa K; Yoshinari K; Sueyoshi T; Negishi M; Miwa M
Mol Pharmacol; 2005 Mar; 67(3):845-55. PubMed ID: 15557560
[TBL] [Abstract][Full Text] [Related]
4. Zearalenone activates pregnane X receptor, constitutive androstane receptor and aryl hydrocarbon receptor and corresponding phase I target genes mRNA in primary cultures of human hepatocytes.
Ayed-Boussema I; Pascussi JM; Maurel P; Bacha H; Hassen W
Environ Toxicol Pharmacol; 2011 Jan; 31(1):79-87. PubMed ID: 21787672
[TBL] [Abstract][Full Text] [Related]
5. Glucocorticoid receptor enhancement of pregnane X receptor-mediated CYP2B6 regulation in primary human hepatocytes.
Wang H; Faucette SR; Gilbert D; Jolley SL; Sueyoshi T; Negishi M; LeCluyse EL
Drug Metab Dispos; 2003 May; 31(5):620-30. PubMed ID: 12695351
[TBL] [Abstract][Full Text] [Related]
6. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
Cerveny L; Svecova L; Anzenbacherova E; Vrzal R; Staud F; Dvorak Z; Ulrichova J; Anzenbacher P; Pavek P
Drug Metab Dispos; 2007 Jul; 35(7):1032-41. PubMed ID: 17392393
[TBL] [Abstract][Full Text] [Related]
7. Colchicine down-regulates cytochrome P450 2B6, 2C8, 2C9, and 3A4 in human hepatocytes by affecting their glucocorticoid receptor-mediated regulation.
Dvorak Z; Modriansky M; Pichard-Garcia L; Balaguer P; Vilarem MJ; Ulrichová J; Maurel P; Pascussi JM
Mol Pharmacol; 2003 Jul; 64(1):160-9. PubMed ID: 12815172
[TBL] [Abstract][Full Text] [Related]
8. The nuclear receptors pregnane X receptor and constitutive androstane receptor contribute to the impact of fipronil on hepatic gene expression linked to thyroid hormone metabolism.
Roques BB; Leghait J; Lacroix MZ; Lasserre F; Pineau T; Viguié C; Martin PG
Biochem Pharmacol; 2013 Oct; 86(7):997-1039. PubMed ID: 23962444
[TBL] [Abstract][Full Text] [Related]
9. Regulation of the rat glutathione S-transferase A2 gene by glucocorticoids: involvement of both the glucocorticoid and pregnane X receptors.
Falkner KC; Pinaire JA; Xiao GH; Geoghegan TE; Prough RA
Mol Pharmacol; 2001 Sep; 60(3):611-9. PubMed ID: 11502894
[TBL] [Abstract][Full Text] [Related]
10. Regulation of the human CYP2B6 gene by the nuclear pregnane X receptor.
Goodwin B; Moore LB; Stoltz CM; McKee DD; Kliewer SA
Mol Pharmacol; 2001 Sep; 60(3):427-31. PubMed ID: 11502872
[TBL] [Abstract][Full Text] [Related]
11. Regulatory cross-talk between drug metabolism and lipid homeostasis: constitutive androstane receptor and pregnane X receptor increase Insig-1 expression.
Roth A; Looser R; Kaufmann M; Blättler SM; Rencurel F; Huang W; Moore DD; Meyer UA
Mol Pharmacol; 2008 Apr; 73(4):1282-9. PubMed ID: 18187584
[TBL] [Abstract][Full Text] [Related]
12. Azole antimycotics differentially affect rifampicin-induced pregnane X receptor-mediated CYP3A4 gene expression.
Svecova L; Vrzal R; Burysek L; Anzenbacherova E; Cerveny L; Grim J; Trejtnar F; Kunes J; Pour M; Staud F; Anzenbacher P; Dvorak Z; Pavek P
Drug Metab Dispos; 2008 Feb; 36(2):339-48. PubMed ID: 17998298
[TBL] [Abstract][Full Text] [Related]
13. Differences in Gene Regulation by Dual Ligands of Nuclear Receptors Constitutive Androstane Receptor (CAR) and Pregnane X Receptor (PXR) in HepG2 Cells Stably Expressing CAR/PXR.
Kanno Y; Tanuma N; Yazawa S; Zhao S; Inaba M; Nakamura S; Nemoto K; Inouye Y
Drug Metab Dispos; 2016 Aug; 44(8):1158-63. PubMed ID: 27197997
[TBL] [Abstract][Full Text] [Related]
14. Genomewide comparison of the inducible transcriptomes of nuclear receptors CAR, PXR and PPARα in primary human hepatocytes.
Kandel BA; Thomas M; Winter S; Damm G; Seehofer D; Burk O; Schwab M; Zanger UM
Biochim Biophys Acta; 2016 Sep; 1859(9):1218-1227. PubMed ID: 26994748
[TBL] [Abstract][Full Text] [Related]
15. Induction of CYP2C genes in human hepatocytes in primary culture.
Gerbal-Chaloin S; Pascussi JM; Pichard-Garcia L; Daujat M; Waechter F; Fabre JM; Carrère N; Maurel P
Drug Metab Dispos; 2001 Mar; 29(3):242-51. PubMed ID: 11181490
[TBL] [Abstract][Full Text] [Related]
16. Dexamethasone induces pregnane X receptor and retinoid X receptor-alpha expression in human hepatocytes: synergistic increase of CYP3A4 induction by pregnane X receptor activators.
Pascussi JM; Drocourt L; Fabre JM; Maurel P; Vilarem MJ
Mol Pharmacol; 2000 Aug; 58(2):361-72. PubMed ID: 10908304
[TBL] [Abstract][Full Text] [Related]
17. Effect of aflatoxin B1 on nuclear receptors PXR, CAR, and AhR and their target cytochromes P450 mRNA expression in primary cultures of human hepatocytes.
Ayed-Boussema I; Pascussi JM; Maurel P; Bacha H; Hassen W
Int J Toxicol; 2012; 31(1):86-93. PubMed ID: 21994236
[TBL] [Abstract][Full Text] [Related]
18. Modulation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) activation by ursolic acid (UA) attenuates rifampin-isoniazid cytotoxicity.
Chang HY; Chen CJ; Ma WC; Cheng WK; Lin YN; Lee YR; Chen JJ; Lim YP
Phytomedicine; 2017 Dec; 36():37-49. PubMed ID: 29157826
[TBL] [Abstract][Full Text] [Related]
19. Interleukin 1beta inhibits CAR-induced expression of hepatic genes involved in drug and bilirubin clearance.
Assenat E; Gerbal-Chaloin S; Larrey D; Saric J; Fabre JM; Maurel P; Vilarem MJ; Pascussi JM
Hepatology; 2004 Oct; 40(4):951-60. PubMed ID: 15382119
[TBL] [Abstract][Full Text] [Related]
20. Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells.
Westerink WM; Schoonen WG
Toxicol In Vitro; 2007 Dec; 21(8):1581-91. PubMed ID: 17637504
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
