BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

357 related articles for article (PubMed ID: 16608920)

  • 41. Role of constitutive androstane receptor in Toll-like receptor-mediated regulation of gene expression of hepatic drug-metabolizing enzymes and transporters.
    Shah P; Guo T; Moore DD; Ghose R
    Drug Metab Dispos; 2014 Jan; 42(1):172-81. PubMed ID: 24194512
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Allyl isothiocyanate (AITC) inhibits pregnane X receptor (PXR) and constitutive androstane receptor (CAR) activation and protects against acetaminophen- and amiodarone-induced cytotoxicity.
    Lim YP; Cheng CH; Chen WC; Chang SY; Hung DZ; Chen JJ; Wan L; Ma WC; Lin YH; Chen CY; Yokoi T; Nakajima M; Chen CJ
    Arch Toxicol; 2015 Jan; 89(1):57-72. PubMed ID: 25069801
    [TBL] [Abstract][Full Text] [Related]  

  • 43. The ratio of constitutive androstane receptor to pregnane X receptor determines the activity of guggulsterone against the Cyp2b10 promoter.
    Ding X; Staudinger JL
    J Pharmacol Exp Ther; 2005 Jul; 314(1):120-7. PubMed ID: 15833898
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Transcriptional regulation of human UGT1A1 gene expression through distal and proximal promoter motifs: implication of defects in the UGT1A1 gene promoter.
    Sugatani J; Mizushima K; Osabe M; Yamakawa K; Kakizaki S; Takagi H; Mori M; Ikari A; Miwa M
    Naunyn Schmiedebergs Arch Pharmacol; 2008 Jun; 377(4-6):597-605. PubMed ID: 18172616
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Human pregnane X receptor is activated by dibenzazepine carbamate-based inhibitors of constitutive androstane receptor.
    Jeske J; Windshügel B; Thasler WE; Schwab M; Burk O
    Arch Toxicol; 2017 Jun; 91(6):2375-2390. PubMed ID: 28289823
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Transcriptional activation of PPARalpha by phenobarbital in the absence of CAR and PXR.
    Tamasi V; Juvan P; Beer M; Rozman D; Meyer UA
    Mol Pharm; 2009; 6(5):1573-81. PubMed ID: 19708687
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Expression and activity of p-glycoprotein elevated by dexamethasone in cultured retinal pigment epithelium involve glucocorticoid receptor and pregnane X receptor.
    Zhang Y; Lu M; Sun X; Li C; Kuang X; Ruan X
    Invest Ophthalmol Vis Sci; 2012 Jun; 53(7):3508-15. PubMed ID: 22570346
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Expression of cytochromes P450, conjugating enzymes and nuclear receptors in human hepatoma HepaRG cells.
    Aninat C; Piton A; Glaise D; Le Charpentier T; Langouët S; Morel F; Guguen-Guillouzo C; Guillouzo A
    Drug Metab Dispos; 2006 Jan; 34(1):75-83. PubMed ID: 16204462
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Hepatic expression of thyroid hormone-responsive spot 14 protein is regulated by constitutive androstane receptor (NR1I3).
    Breuker C; Moreau A; Lakhal L; Tamasi V; Parmentier Y; Meyer U; Maurel P; Lumbroso S; Vilarem MJ; Pascussi JM
    Endocrinology; 2010 Apr; 151(4):1653-61. PubMed ID: 20185760
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Establishing Transcriptional Signatures to Differentiate PXR-, CAR-, and AhR-Mediated Regulation of Drug Metabolism and Transport Genes in Cryopreserved Human Hepatocytes.
    Moscovitz JE; Kalgutkar AS; Nulick K; Johnson N; Lin Z; Goosen TC; Weng Y
    J Pharmacol Exp Ther; 2018 May; 365(2):262-271. PubMed ID: 29440451
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification.
    Maglich JM; Stoltz CM; Goodwin B; Hawkins-Brown D; Moore JT; Kliewer SA
    Mol Pharmacol; 2002 Sep; 62(3):638-46. PubMed ID: 12181440
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Orphan nuclear receptor binding site in the human inducible nitric oxide synthase promoter mediates responsiveness to steroid and xenobiotic ligands.
    Toell A; Kröncke KD; Kleinert H; Carlberg C
    J Cell Biochem; 2002; 85(1):72-82. PubMed ID: 11891851
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Role of the nuclear xenobiotic receptors CAR and PXR in induction of cytochromes P450 by non-dioxinlike polychlorinated biphenyls in cultured rat hepatocytes.
    Gährs M; Roos R; Andersson PL; Schrenk D
    Toxicol Appl Pharmacol; 2013 Oct; 272(1):77-85. PubMed ID: 23770461
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor.
    Xie W; Yeuh MF; Radominska-Pandya A; Saini SP; Negishi Y; Bottroff BS; Cabrera GY; Tukey RH; Evans RM
    Proc Natl Acad Sci U S A; 2003 Apr; 100(7):4150-5. PubMed ID: 12644700
    [TBL] [Abstract][Full Text] [Related]  

  • 55. PXR-mediated transcriptional activation of CYP3A4 by cryptotanshinone and tanshinone IIA.
    Yu C; Ye S; Sun H; Liu Y; Gao L; Shen C; Chen S; Zeng S
    Chem Biol Interact; 2009 Jan; 177(1):58-64. PubMed ID: 18805405
    [TBL] [Abstract][Full Text] [Related]  

  • 56. GW4064, an agonist of farnesoid X receptor, represses CYP3A4 expression in human hepatocytes by inducing small heterodimer partner expression.
    Zhang S; Pan X; Jeong H
    Drug Metab Dispos; 2015 May; 43(5):743-8. PubMed ID: 25725071
    [TBL] [Abstract][Full Text] [Related]  

  • 57. The mycotoxin, patulin, increases the expression of PXR and AhR and their target cytochrome P450s in primary cultured human hepatocytes.
    Ayed-Boussema I; Pascussi JM; Rjiba K; Maurel P; Bacha H; Hassen W
    Drug Chem Toxicol; 2012 Jul; 35(3):241-50. PubMed ID: 21939362
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Conservation of signaling pathways of xenobiotic-sensing orphan nuclear receptors, chicken xenobiotic receptor, constitutive androstane receptor, and pregnane X receptor, from birds to humans.
    Handschin C; Podvinec M; Stöckli J; Hoffmann K; Meyer UA
    Mol Endocrinol; 2001 Sep; 15(9):1571-85. PubMed ID: 11518807
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Drug-drug interactions by azole antifungals: Beyond a dogma of CYP3A4 enzyme activity inhibition.
    Dvorak Z
    Toxicol Lett; 2011 Apr; 202(2):129-32. PubMed ID: 21333771
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Inhibition of CYP3A4 expression by ketoconazole is mediated by the disruption of pregnane X receptor, steroid receptor coactivator-1, and hepatocyte nuclear factor 4alpha interaction.
    Lim YP; Kuo SC; Lai ML; Huang JD
    Pharmacogenet Genomics; 2009 Jan; 19(1):11-24. PubMed ID: 19077665
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 18.