These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

181 related articles for article (PubMed ID: 16610798)

  • 1. A chemical switch for the modulation of the functional activity of higher homologues of histamine on the human histamine H3 receptor: effect of various substitutions at the primary amino function.
    Govoni M; Lim HD; El-Atmioui D; Menge WM; Timmerman H; Bakker RA; Leurs R; De Esch IJ
    J Med Chem; 2006 Apr; 49(8):2549-57. PubMed ID: 16610798
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Compared pharmacology of human histamine H3 and H4 receptors: structure-activity relationships of histamine derivatives.
    Gbahou F; Vincent L; Humbert-Claude M; Tardivel-Lacombe J; Chabret C; Arrang JM
    Br J Pharmacol; 2006 Apr; 147(7):744-54. PubMed ID: 16432504
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and structure-activity relationships of conformationally constrained histamine H(3) receptor agonists.
    Kitbunnadaj R; Zuiderveld OP; De Esch IJ; Vollinga RC; Bakker R; Lutz M; Spek AL; Cavoy E; Deltent MF; Menge WM; Timmerman H; Leurs R
    J Med Chem; 2003 Dec; 46(25):5445-57. PubMed ID: 14640553
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and pharmacological identification of neutral histamine H1-receptor antagonists.
    Govoni M; Bakker RA; van de Wetering I; Smit MJ; Menge WM; Timmerman H; Elz S; Schunack W; Leurs R
    J Med Chem; 2003 Dec; 46(26):5812-24. PubMed ID: 14667234
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Clobenpropit analogs as dual activity ligands for the histamine H3 and H4 receptors: synthesis, pharmacological evaluation, and cross-target QSAR studies.
    Lim HD; Istyastono EP; van de Stolpe A; Romeo G; Gobbi S; Schepers M; Lahaye R; Menge WM; Zuiderveld OP; Jongejan A; Smits RA; Bakker RA; Haaksma EE; Leurs R; de Esch IJ
    Bioorg Med Chem; 2009 Jun; 17(11):3987-94. PubMed ID: 19414267
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Histamine H3 and H4 receptor affinity of branched 3-(1H-imidazol-4-yl)propyl N-alkylcarbamates.
    Łazewska D; Wiecek M; Ligneau X; Kottke T; Weizel L; Seifert R; Schunack W; Stark H; Kieć-Kononowicz K
    Bioorg Med Chem Lett; 2009 Dec; 19(23):6682-5. PubMed ID: 19846299
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural requirements for inverse agonism and neutral antagonism of indole-, benzimidazole-, and thienopyrrole-derived histamine H4 receptor ligands.
    Schneider EH; Strasser A; Thurmond RL; Seifert R
    J Pharmacol Exp Ther; 2010 Aug; 334(2):513-21. PubMed ID: 20484153
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Constitutive activity of histamine h(3) receptors stably expressed in SK-N-MC cells: display of agonism and inverse agonism by H(3) antagonists.
    Wieland K; Bongers G; Yamamoto Y; Hashimoto T; Yamatodani A; Menge WM; Timmerman H; Lovenberg TW; Leurs R
    J Pharmacol Exp Ther; 2001 Dec; 299(3):908-14. PubMed ID: 11714875
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Search for histamine H(3) receptor ligands with combined inhibitory potency at histamine N-methyltransferase: omega-piperidinoalkanamine derivatives.
    Grassmann S; Apelt J; Ligneau X; Pertz HH; Arrang JM; Ganellin CR; Schwartz JC; Schunack W; Stark H
    Arch Pharm (Weinheim); 2004 Oct; 337(10):533-45. PubMed ID: 15476285
    [TBL] [Abstract][Full Text] [Related]  

  • 10. G protein-dependent pharmacology of histamine H3 receptor ligands: evidence for heterogeneous active state receptor conformations.
    Krueger KM; Witte DG; Ireland-Denny L; Miller TR; Baranowski JL; Buckner S; Milicic I; Esbenshade TA; Hancock AA
    J Pharmacol Exp Ther; 2005 Jul; 314(1):271-81. PubMed ID: 15821027
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Receptor-specific functional efficacies of alkyl imidazoles as dual histamine H3/H4 receptor ligands.
    Kottke T; Sander K; Weizel L; Schneider EH; Seifert R; Stark H
    Eur J Pharmacol; 2011 Mar; 654(3):200-8. PubMed ID: 21237145
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Stereochemical diversity-oriented conformational restriction strategy. Development of potent histamine H3 and/or H4 receptor antagonists with an imidazolylcyclopropane structure.
    Watanabe M; Kazuta Y; Hayashi H; Yamada S; Matsuda A; Shuto S
    J Med Chem; 2006 Sep; 49(18):5587-96. PubMed ID: 16942032
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Piperidine variations in search for non-imidazole histamine H(3) receptor ligands.
    Łazewska D; Kuder K; Ligneau X; Schwartz JC; Schunack W; Stark H; Kieć-Kononowicz K
    Bioorg Med Chem; 2008 Sep; 16(18):8729-36. PubMed ID: 18774720
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tritium-labeled N(1)-[3-(1H-imidazol-4-yl)propyl]-N(2)-propionylguanidine ([(3)H]UR-PI294), a high-affinity histamine H(3) and H(4) receptor radioligand.
    Igel P; Schnell D; Bernhardt G; Seifert R; Buschauer A
    ChemMedChem; 2009 Feb; 4(2):225-31. PubMed ID: 19101971
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 2,4-Diaminopyrimidines as histamine H4 receptor ligands--Scaffold optimization and pharmacological characterization.
    Sander K; Kottke T; Tanrikulu Y; Proschak E; Weizel L; Schneider EH; Seifert R; Schneider G; Stark H
    Bioorg Med Chem; 2009 Oct; 17(20):7186-96. PubMed ID: 19773175
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Agonist/antagonist modulation in a series of 2-aryl benzimidazole H4 receptor ligands.
    Savall BM; Edwards JP; Venable JD; Buzard DJ; Thurmond R; Hack M; McGovern P
    Bioorg Med Chem Lett; 2010 Jun; 20(11):3367-71. PubMed ID: 20452213
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel nonimidazole histamine H3 receptor antagonists: 1-(4-(phenoxymethyl)benzyl)piperidines and related compounds.
    Mikó T; Ligneau X; Pertz HH; Ganellin CR; Arrang JM; Schwartz JC; Schunack W; Stark H
    J Med Chem; 2003 Apr; 46(8):1523-30. PubMed ID: 12672253
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A new family of H3 receptor antagonists based on the natural product Conessine.
    Santora VJ; Covel JA; Hayashi R; Hofilena BJ; Ibarra JB; Pulley MD; Weinhouse MI; Sengupta D; Duffield JJ; Semple G; Webb RR; Sage C; Ren A; Pereira G; Knudsen J; Edwards JE; Suarez M; Frazer J; Thomsen W; Hauser E; Whelan K; Grottick AJ
    Bioorg Med Chem Lett; 2008 Feb; 18(4):1490-4. PubMed ID: 18194865
    [TBL] [Abstract][Full Text] [Related]  

  • 19. N(alpha)-imidazolylalkyl and pyridylalkyl derivatives of histaprodifen: synthesis and in vitro evaluation of highly potent histamine H(1)-receptor agonists.
    Menghin S; Pertz HH; Kramer K; Seifert R; Schunack W; Elz S
    J Med Chem; 2003 Dec; 46(25):5458-70. PubMed ID: 14640554
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and structure-activity relationships of indole and benzimidazole piperazines as histamine H(4) receptor antagonists.
    Terzioglu N; van Rijn RM; Bakker RA; De Esch IJ; Leurs R
    Bioorg Med Chem Lett; 2004 Nov; 14(21):5251-6. PubMed ID: 15454206
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.