BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

108 related articles for article (PubMed ID: 16610806)

  • 1. New NO-releasing pharmacodynamic hybrids of losartan and its active metabolite: design, synthesis, and biopharmacological properties.
    Breschi MC; Calderone V; Digiacomo M; Macchia M; Martelli A; Martinotti E; Minutolo F; Rapposelli S; Rossello A; Testai L; Balsamo A
    J Med Chem; 2006 Apr; 49(8):2628-39. PubMed ID: 16610806
    [TBL] [Abstract][Full Text] [Related]  

  • 2. NO-sartans: a new class of pharmacodynamic hybrids as cardiovascular drugs.
    Breschi MC; Calderone V; Digiacomo M; Martelli A; Martinotti E; Minutolo F; Rapposelli S; Balsamo A
    J Med Chem; 2004 Nov; 47(23):5597-600. PubMed ID: 15509155
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of angiotensin II antagonism displayed by Ib, a novel nonpeptide angiotensin AT(1) receptor antagonist.
    Wu J; Wang Q; Guo J; Hu Z; Yin Z; Xu J; Wu X
    Eur J Pharmacol; 2008 Jul; 589(1-3):220-4. PubMed ID: 18571160
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design and synthesis of new tetrazolyl- and carboxy-biphenylylmethyl-quinazolin-4-one derivatives as angiotensin II AT1 receptor antagonists.
    Ismail MA; Barker S; Abou el-Ella DA; Abouzid KA; Toubar RA; Todd MH
    J Med Chem; 2006 Mar; 49(5):1526-35. PubMed ID: 16509571
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis, binding studies and in vivo biological evaluation of novel non-peptide antihypertensive analogues.
    Mavromoustakos T; Moutevelis-Minakakis P; Kokotos CG; Kontogianni P; Politi A; Zoumpoulakis P; Findlay J; Cox A; Balmforth A; Zoga A; Iliodromitis E
    Bioorg Med Chem; 2006 Jul; 14(13):4353-60. PubMed ID: 16546395
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis, structural studies, biological evaluation, and computational simulations of novel potent AT(1) angiotensin II receptor antagonists based on the 4-phenylquinoline structure.
    Cappelli A; Pericot Mohr Gl Gl; Gallelli A; Rizzo M; Anzini M; Vomero S; Mennuni L; Ferrari F; Makovec F; Menziani MC; De Benedetti PG; Giorgi G
    J Med Chem; 2004 May; 47(10):2574-86. PubMed ID: 15115399
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Selenosartans: novel selenophene analogues of milfasartan and eprosartan.
    Grange RL; Ziogas J; North AJ; Angus JA; Schiesser CH
    Bioorg Med Chem Lett; 2008 Feb; 18(3):1241-4. PubMed ID: 18191398
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Losartan-antioxidant hybrids: novel molecules for the prevention of hypertension-induced cardiovascular damage.
    García G; Rodríguez-Puyol M; Alajarín R; Serrano I; Sánchez-Alonso P; Griera M; Vaquero JJ; Rodríguez-Puyol D; Alvarez-Builla J; Díez-Marqués ML
    J Med Chem; 2009 Nov; 52(22):7220-7. PubMed ID: 19863054
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and antihypertensive activity of pyrimidin-4(3H)-one derivatives as losartan analogue for new angiotensin II receptor type 1 (AT1) antagonists.
    Kim TW; Yoo BW; Lee JK; Kim JH; Lee KT; Chi YH; Lee JY
    Bioorg Med Chem Lett; 2012 Feb; 22(4):1649-54. PubMed ID: 22264484
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Beneficial effects of the combination of amlodipine and losartan for lowering blood pressure in spontaneously hypertensive rats.
    Choi SM; Seo MJ; Kang KK; Kim JH; Ahn BO; Yoo M
    Arch Pharm Res; 2009 Mar; 32(3):353-8. PubMed ID: 19387578
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and biological evaluation of novel potent angiotensin II receptor antagonists with anti-hypertension effect.
    Nie YY; Da YJ; Zheng H; Yang XX; Jia L; Wen CH; Liang LS; Tian J; Chen ZL
    Bioorg Med Chem; 2012 Apr; 20(8):2747-61. PubMed ID: 22410249
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Computer--based drug design, synthesis and biological evaluation of new pyrimidinone derivatives linked to arylpiperazine and 2'-carbethoxy-biphenylylmethyl moeities as alpha1-adrenoceptor antagonists and angiotensin II AT1 receptor antagonists.
    Ismail MA; Abou El Ella DA; Abouzid KA; Al-Ansary GH
    Pharmazie; 2010 Nov; 65(11):794-800. PubMed ID: 21155384
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis and pharmacological screening of novel antihypertensive agents using hybrid approach.
    Bhandari SV; Bothara KG; Patil AA; Chitre TS; Sarkate AP; Gore ST; Dangre SC; Khachane CV
    Bioorg Med Chem; 2009 Jan; 17(1):390-400. PubMed ID: 19036593
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effects of antihypertensive drugs on capillary rarefaction in spontaneously hypertensive rats: intravital microscopy and histologic analysis.
    Sabino B; Lessa MA; Nascimento AR; Rodrigues CA; Henriques Md; Garzoni LR; Levy BI; Tibiriçá E
    J Cardiovasc Pharmacol; 2008 Apr; 51(4):402-9. PubMed ID: 18427284
    [TBL] [Abstract][Full Text] [Related]  

  • 15. New losartan-hydrocaffeic acid hybrids as antihypertensive-antioxidant dual drugs: Ester, amide and amine linkers.
    García G; Serrano I; Sánchez-Alonso P; Rodríguez-Puyol M; Alajarín R; Griera M; Vaquero JJ; Rodríguez-Puyol D; Alvarez-Builla J; Díez-Marqués ML
    Eur J Med Chem; 2012 Apr; 50():90-101. PubMed ID: 22336384
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Exercise training combined with angiotensin II receptor blockade limits post-infarct ventricular remodelling in rats.
    Xu X; Wan W; Ji L; Lao S; Powers AS; Zhao W; Erikson JM; Zhang JQ
    Cardiovasc Res; 2008 Jun; 78(3):523-32. PubMed ID: 18252761
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Antihypertensive and renal protective effects of renin-angiotensin system blockade in uremic rats treated with erythropoietin.
    Lebel M; Rodrigue ME; Agharazii M; Larivière R
    Am J Hypertens; 2006 Dec; 19(12):1286-92. PubMed ID: 17161776
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Angiotensin II type 1 receptor as a novel therapeutic target in rheumatoid arthritis: in vivo analyses in rodent models of arthritis and ex vivo analyses in human inflammatory synovitis.
    Price A; Lockhart JC; Ferrell WR; Gsell W; McLean S; Sturrock RD
    Arthritis Rheum; 2007 Feb; 56(2):441-7. PubMed ID: 17265479
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Review of the molecular pharmacology of Losartan and its possible relevance to stroke prevention in patients with hypertension.
    Díez J
    Clin Ther; 2006 Jun; 28(6):832-48. PubMed ID: 16860167
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis and biological activity of 6-substituted carbamoyl benzimidazoles as new nonpeptidic angiotensin II AT₁ receptor antagonists.
    Zhang J; Wang JL; Zhou ZM; Li ZH; Xue WZ; Xu D; Hao LP; Han XF; Fei F; Liu T; Liang AH
    Bioorg Med Chem; 2012 Jul; 20(14):4208-16. PubMed ID: 22727371
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.