146 related articles for article (PubMed ID: 16610809)
1. Synthesis and biological evaluation of cyclopropyl analogues of fosmidomycin as potent Plasmodium falciparum growth inhibitors.
Devreux V; Wiesner J; Goeman JL; Van der Eycken J; Jomaa H; Van Calenbergh S
J Med Chem; 2006 Apr; 49(8):2656-60. PubMed ID: 16610809
[TBL] [Abstract][Full Text] [Related]
2. Evaluation of fosmidomycin analogs as inhibitors of the Synechocystis sp. PCC6803 1-deoxy-D-xylulose 5-phosphate reductoisomerase.
Woo YH; Fernandes RP; Proteau PJ
Bioorg Med Chem; 2006 Apr; 14(7):2375-85. PubMed ID: 16310360
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and evaluation of alpha,beta-unsaturated alpha-aryl-substituted fosmidomycin analogues as DXR inhibitors.
Devreux V; Wiesner J; Jomaa H; Van der Eycken J; Van Calenbergh S
Bioorg Med Chem Lett; 2007 Sep; 17(17):4920-3. PubMed ID: 17583502
[TBL] [Abstract][Full Text] [Related]
4. Double ester prodrugs of FR900098 display enhanced in-vitro antimalarial activity.
Wiesner J; Ortmann R; Jomaa H; Schlitzer M
Arch Pharm (Weinheim); 2007 Dec; 340(12):667-9. PubMed ID: 17994601
[TBL] [Abstract][Full Text] [Related]
5. Synthesis of alpha-substituted fosmidomycin analogues as highly potent Plasmodium falciparum growth inhibitors.
Haemers T; Wiesner J; Van Poecke S; Goeman J; Henschker D; Beck E; Jomaa H; Van Calenbergh S
Bioorg Med Chem Lett; 2006 Apr; 16(7):1888-91. PubMed ID: 16439126
[TBL] [Abstract][Full Text] [Related]
6. Towards new antimalarial drugs: synthesis of non-hydrolyzable phosphate mimics as feed for a predictive QSAR study on 1-deoxy-D-xylulose-5-phosphate reductoisomerase inhibitors.
Giessmann D; Heidler P; Haemers T; Van Calenbergh S; Reichenberg A; Jomaa H; Weidemeyer C; Sanderbrand S; Wiesner J; Link A
Chem Biodivers; 2008 Apr; 5(4):643-56. PubMed ID: 18421757
[TBL] [Abstract][Full Text] [Related]
7. A fragment-based approach to understanding inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase.
Mercklé L; de Andrés-Gómez A; Dick B; Cox RJ; Godfrey CR
Chembiochem; 2005 Oct; 6(10):1866-74. PubMed ID: 16116659
[TBL] [Abstract][Full Text] [Related]
8. Molecular epidemiology of malaria in Cameroon. XXV. In vitro activity of fosmidomycin and its derivatives against fresh clinical isolates of Plasmodium falciparum and sequence analysis of 1-deoxy-D-xylulose 5-phosphate reductoisomerase.
Tahar R; Basco LK
Am J Trop Med Hyg; 2007 Aug; 77(2):214-20. PubMed ID: 17690389
[TBL] [Abstract][Full Text] [Related]
9. Studies addressing the importance of charge in the binding of fosmidomycin-like molecules to deoxyxylulosephosphate reductoisomerase.
Perruchon J; Ortmann R; Altenkämper M; Silber K; Wiesner J; Jomaa H; Klebe G; Schlitzer M
ChemMedChem; 2008 Aug; 3(8):1232-41. PubMed ID: 18470849
[TBL] [Abstract][Full Text] [Related]
10. 1-Deoxy-D-xylulose 5-phosphate reductoisomerase: an overview.
Proteau PJ
Bioorg Chem; 2004 Dec; 32(6):483-93. PubMed ID: 15530989
[TBL] [Abstract][Full Text] [Related]
11. Substrate analogs for the investigation of deoxyxylulose 5-phosphate reductoisomerase inhibition: synthesis and evaluation.
Phaosiri C; Proteau PJ
Bioorg Med Chem Lett; 2004 Nov; 14(21):5309-12. PubMed ID: 15454217
[TBL] [Abstract][Full Text] [Related]
12. Divergent strategy for the synthesis of alpha-aryl-substituted fosmidomycin analogues.
Devreux V; Wiesner J; Jomaa H; Rozenski J; Van der Eycken J; Van Calenbergh S
J Org Chem; 2007 May; 72(10):3783-9. PubMed ID: 17428097
[TBL] [Abstract][Full Text] [Related]
13. Novel deoxyxylulosephosphate-reductoisomerase inhibitors: fosmidomycin derivatives with spacious acyl residues.
Ortmann R; Wiesner J; Silber K; Klebe G; Jomaa H; Schlitzer M
Arch Pharm (Weinheim); 2007 Sep; 340(9):483-90. PubMed ID: 17806130
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and antimalarial activity of chain substituted pivaloyloxymethyl ester analogues of Fosmidomycin and FR900098.
Kurz T; Schlüter K; Kaula U; Bergmann B; Walter RD; Geffken D
Bioorg Med Chem; 2006 Aug; 14(15):5121-35. PubMed ID: 16679022
[TBL] [Abstract][Full Text] [Related]
15. Antimalarial activity of N(6)-substituted adenosine derivatives. Part 3.
Herforth C; Wiesner J; Heidler P; Sanderbrand S; Van Calenbergh S; Jomaa H; Link A
Bioorg Med Chem; 2004 Feb; 12(4):755-62. PubMed ID: 14759735
[TBL] [Abstract][Full Text] [Related]
16. AFMoC enhances predictivity of 3D QSAR: a case study with DOXP-reductoisomerase.
Silber K; Heidler P; Kurz T; Klebe G
J Med Chem; 2005 May; 48(10):3547-63. PubMed ID: 15887963
[TBL] [Abstract][Full Text] [Related]
17. Conformationally restrained aromatic analogues of fosmidomycin and FR900098.
Kurz T; Schlüter K; Pein M; Behrendt C; Bergmann B; Walter RD
Arch Pharm (Weinheim); 2007 Jul; 340(7):339-44. PubMed ID: 17611943
[TBL] [Abstract][Full Text] [Related]
18. The crystal structure of E.coli 1-deoxy-D-xylulose-5-phosphate reductoisomerase in a ternary complex with the antimalarial compound fosmidomycin and NADPH reveals a tight-binding closed enzyme conformation.
Mac Sweeney A; Lange R; Fernandes RP; Schulz H; Dale GE; Douangamath A; Proteau PJ; Oefner C
J Mol Biol; 2005 Jan; 345(1):115-27. PubMed ID: 15567415
[TBL] [Abstract][Full Text] [Related]
19. Alkoxycarbonyloxyethyl ester prodrugs of FR900098 with improved in vivo antimalarial activity.
Ortmann R; Wiesner J; Reichenberg A; Henschker D; Beck E; Jomaa H; Schlitzer M
Arch Pharm (Weinheim); 2005 Jul; 338(7):305-14. PubMed ID: 15996004
[TBL] [Abstract][Full Text] [Related]
20. Reverse
Abdullaziz MA; Takada S; Illarionov B; Pessanha de Carvalho L; Sakamoto Y; Höfmann S; Knak T; Kiffe-Delf AL; Mazzone F; Pfeffer K; Kalscheuer R; Bacher A; Held J; Fischer M; Tanaka N; Kurz T
ACS Infect Dis; 2024 May; 10(5):1739-1752. PubMed ID: 38647213
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
