1189 related articles for article (PubMed ID: 16612385)
1. Production of the antimalarial drug precursor artemisinic acid in engineered yeast.
Ro DK; Paradise EM; Ouellet M; Fisher KJ; Newman KL; Ndungu JM; Ho KA; Eachus RA; Ham TS; Kirby J; Chang MC; Withers ST; Shiba Y; Sarpong R; Keasling JD
Nature; 2006 Apr; 440(7086):940-3. PubMed ID: 16612385
[TBL] [Abstract][Full Text] [Related]
2. Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of anti-malarial drug precursor, artemisinic acid.
Ro DK; Ouellet M; Paradise EM; Burd H; Eng D; Paddon CJ; Newman JD; Keasling JD
BMC Biotechnol; 2008 Nov; 8():83. PubMed ID: 18983675
[TBL] [Abstract][Full Text] [Related]
3. Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin.
Westfall PJ; Pitera DJ; Lenihan JR; Eng D; Woolard FX; Regentin R; Horning T; Tsuruta H; Melis DJ; Owens A; Fickes S; Diola D; Benjamin KR; Keasling JD; Leavell MD; McPhee DJ; Renninger NS; Newman JD; Paddon CJ
Proc Natl Acad Sci U S A; 2012 Jan; 109(3):E111-8. PubMed ID: 22247290
[TBL] [Abstract][Full Text] [Related]
4. High-level semi-synthetic production of the potent antimalarial artemisinin.
Paddon CJ; Westfall PJ; Pitera DJ; Benjamin K; Fisher K; McPhee D; Leavell MD; Tai A; Main A; Eng D; Polichuk DR; Teoh KH; Reed DW; Treynor T; Lenihan J; Fleck M; Bajad S; Dang G; Dengrove D; Diola D; Dorin G; Ellens KW; Fickes S; Galazzo J; Gaucher SP; Geistlinger T; Henry R; Hepp M; Horning T; Iqbal T; Jiang H; Kizer L; Lieu B; Melis D; Moss N; Regentin R; Secrest S; Tsuruta H; Vazquez R; Westblade LF; Xu L; Yu M; Zhang Y; Zhao L; Lievense J; Covello PS; Keasling JD; Reiling KK; Renninger NS; Newman JD
Nature; 2013 Apr; 496(7446):528-32. PubMed ID: 23575629
[TBL] [Abstract][Full Text] [Related]
5. Artemisia annua L. (Asteraceae) trichome-specific cDNAs reveal CYP71AV1, a cytochrome P450 with a key role in the biosynthesis of the antimalarial sesquiterpene lactone artemisinin.
Teoh KH; Polichuk DR; Reed DW; Nowak G; Covello PS
FEBS Lett; 2006 Feb; 580(5):1411-6. PubMed ID: 16458889
[TBL] [Abstract][Full Text] [Related]
6. High-level production of amorpha-4,11-diene, a precursor of the antimalarial agent artemisinin, in Escherichia coli.
Tsuruta H; Paddon CJ; Eng D; Lenihan JR; Horning T; Anthony LC; Regentin R; Keasling JD; Renninger NS; Newman JD
PLoS One; 2009; 4(2):e4489. PubMed ID: 19221601
[TBL] [Abstract][Full Text] [Related]
7. Artemisinin and sesquiterpene precursors in dead and green leaves of Artemisia annua L. crops.
Lommen WJ; Elzinga S; Verstappen FW; Bouwmeester HJ
Planta Med; 2007 Aug; 73(10):1133-9. PubMed ID: 17628838
[TBL] [Abstract][Full Text] [Related]
8. Identification of intermediates and enzymes involved in the early steps of artemisinin biosynthesis in Artemisia annua.
Bertea CM; Freije JR; van der Woude H; Verstappen FW; Perk L; Marquez V; De Kraker JW; Posthumus MA; Jansen BJ; de Groot A; Franssen MC; Bouwmeester HJ
Planta Med; 2005 Jan; 71(1):40-7. PubMed ID: 15678372
[TBL] [Abstract][Full Text] [Related]
9. Functional Analysis of Amorpha-4,11-Diene Synthase (ADS) Homologs from Non-Artemisinin-Producing Artemisia Species: The Discovery of Novel Koidzumiol and (+)-α-Bisabolol Synthases.
Muangphrom P; Seki H; Suzuki M; Komori A; Nishiwaki M; Mikawa R; Fukushima EO; Muranaka T
Plant Cell Physiol; 2016 Aug; 57(8):1678-88. PubMed ID: 27273626
[TBL] [Abstract][Full Text] [Related]
10. Production of artemisinin by genetically-modified microbes.
Zeng Q; Qiu F; Yuan L
Biotechnol Lett; 2008 Apr; 30(4):581-92. PubMed ID: 18008167
[TBL] [Abstract][Full Text] [Related]
11. Production of the artemisinin precursor amorpha-4,11-diene by engineered Saccharomyces cerevisiae.
Lindahl AL; Olsson ME; Mercke P; Tollbom O; Schelin J; Brodelius M; Brodelius PE
Biotechnol Lett; 2006 Apr; 28(8):571-80. PubMed ID: 16614895
[TBL] [Abstract][Full Text] [Related]
12. Differences in chemical constituents of Artemisia annua L from different geographical regions in China.
Zhang X; Zhao Y; Guo L; Qiu Z; Huang L; Qu X
PLoS One; 2017; 12(9):e0183047. PubMed ID: 28880869
[TBL] [Abstract][Full Text] [Related]
13. Recent advances in artemisinin production through heterologous expression.
Arsenault PR; Wobbe KK; Weathers PJ
Curr Med Chem; 2008; 15(27):2886-96. PubMed ID: 18991643
[TBL] [Abstract][Full Text] [Related]
14. Artemisinin, a novel antimalarial drug: biochemical and molecular approaches for enhanced production.
Abdin MZ; Israr M; Rehman RU; Jain SK
Planta Med; 2003 Apr; 69(4):289-99. PubMed ID: 12709893
[TBL] [Abstract][Full Text] [Related]
15. Artemisinin: current state and perspectives for biotechnological production of an antimalarial drug.
Liu C; Zhao Y; Wang Y
Appl Microbiol Biotechnol; 2006 Aug; 72(1):11-20. PubMed ID: 16773335
[TBL] [Abstract][Full Text] [Related]
16. Artemisinin biosynthesis in growing plants of Artemisia annua. A 13CO2 study.
Schramek N; Wang H; Römisch-Margl W; Keil B; Radykewicz T; Winzenhörlein B; Beerhues L; Bacher A; Rohdich F; Gershenzon J; Liu B; Eisenreich W
Phytochemistry; 2010 Feb; 71(2-3):179-87. PubMed ID: 19932496
[TBL] [Abstract][Full Text] [Related]
17. Developing an industrial artemisinic acid fermentation process to support the cost-effective production of antimalarial artemisinin-based combination therapies.
Lenihan JR; Tsuruta H; Diola D; Renninger NS; Regentin R
Biotechnol Prog; 2008; 24(5):1026-32. PubMed ID: 19194910
[TBL] [Abstract][Full Text] [Related]
18. Transgenic approach to increase artemisinin content in Artemisia annua L.
Tang K; Shen Q; Yan T; Fu X
Plant Cell Rep; 2014 Apr; 33(4):605-15. PubMed ID: 24413765
[TBL] [Abstract][Full Text] [Related]
19. Functional genomics and the biosynthesis of artemisinin.
Covello PS; Teoh KH; Polichuk DR; Reed DW; Nowak G
Phytochemistry; 2007 Jul; 68(14):1864-71. PubMed ID: 17399751
[TBL] [Abstract][Full Text] [Related]
20. Metabolic engineering of artemisinin biosynthesis in Artemisia annua L.
Liu B; Wang H; Du Z; Li G; Ye H
Plant Cell Rep; 2011 May; 30(5):689-94. PubMed ID: 21184232
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
