134 related articles for article (PubMed ID: 16612839)
1. Effects of mutations at conserved TM II residues on ligand binding and activation of mouse 5-HT6 receptor.
Zhang J; Shen CP; Xiao JC; Lanza TJ; Lin LS; Francis BE; Fong TM; Chen RZ
Eur J Pharmacol; 2006 Mar; 534(1-3):77-82. PubMed ID: 16612839
[TBL] [Abstract][Full Text] [Related]
2. Identification of residues in transmembrane regions III and VI that contribute to the ligand binding site of the serotonin 5-HT6 receptor.
Boess FG; Monsma FJ; Sleight AJ
J Neurochem; 1998 Nov; 71(5):2169-77. PubMed ID: 9798944
[TBL] [Abstract][Full Text] [Related]
3. Site-directed mutagenesis of the serotonin 5-hydroxytrypamine2 receptor: identification of amino acids necessary for ligand binding and receptor activation.
Wang CD; Gallaher TK; Shih JC
Mol Pharmacol; 1993 Jun; 43(6):931-40. PubMed ID: 8316224
[TBL] [Abstract][Full Text] [Related]
4. Exploration of the ligand binding site of the human 5-HT(4) receptor by site-directed mutagenesis and molecular modeling.
Mialet J; Dahmoune Y; Lezoualc'h F; Berque-Bestel I; Eftekhari P; Hoebeke J; Sicsic S; Langlois M; Fischmeister R
Br J Pharmacol; 2000 Jun; 130(3):527-38. PubMed ID: 10821780
[TBL] [Abstract][Full Text] [Related]
5. Interaction of tryptamine and ergoline compounds with threonine 196 in the ligand binding site of the 5-hydroxytryptamine6 receptor.
Boess FG; Monsma FJ; Meyer V; Zwingelstein C; Sleight AJ
Mol Pharmacol; 1997 Sep; 52(3):515-23. PubMed ID: 9284367
[TBL] [Abstract][Full Text] [Related]
6. Site-directed mutagenesis of the 5-HT1B receptor increases the affinity of 5-HT for the agonist low-affinity conformation and reduces the intrinsic activity of 5-HT.
Grånäs C; Nordquist J; Mohell N; Larhammar D
Eur J Pharmacol; 2001 Jun; 421(2):69-76. PubMed ID: 11399261
[TBL] [Abstract][Full Text] [Related]
7. Creation, expression, and characterization of a constitutively active mutant of the human serotonin 5-HT6 receptor.
Purohit A; Herrick-Davis K; Teitler M
Synapse; 2003 Mar; 47(3):218-24. PubMed ID: 12494404
[TBL] [Abstract][Full Text] [Related]
8. Differential modes of agonist binding to 5-hydroxytryptamine(2A) serotonin receptors revealed by mutation and molecular modeling of conserved residues in transmembrane region 5.
Shapiro DA; Kristiansen K; Kroeze WK; Roth BL
Mol Pharmacol; 2000 Nov; 58(5):877-86. PubMed ID: 11040033
[TBL] [Abstract][Full Text] [Related]
9. Mapping the binding site pocket of the serotonin 5-Hydroxytryptamine2A receptor. Ser3.36(159) provides a second interaction site for the protonated amine of serotonin but not of lysergic acid diethylamide or bufotenin.
Almaula N; Ebersole BJ; Zhang D; Weinstein H; Sealfon SC
J Biol Chem; 1996 Jun; 271(25):14672-5. PubMed ID: 8663249
[TBL] [Abstract][Full Text] [Related]
10. Whole spectrum analysis of ligand efficacy at constitutively active human wild-type and S267K 5-HT6 receptors in HEK-293F cells.
Romero G; Pujol M; Pérez P; Buschmann H; Pauwels PJ
J Pharmacol Toxicol Methods; 2007; 55(2):144-50. PubMed ID: 16769227
[TBL] [Abstract][Full Text] [Related]
11. Efficacy of selective 5-HT6 receptor ligands determined by monitoring 5-HT6 receptor-mediated cAMP signaling pathways.
Romero G; Sánchez E; Pujol M; Pérez P; Codony X; Holenz J; Buschmann H; Pauwels PJ
Br J Pharmacol; 2006 Aug; 148(8):1133-43. PubMed ID: 16865095
[TBL] [Abstract][Full Text] [Related]
12. Residues in transmembrane regions III and VI contribute to the 5-ht6 receptor ligand binding site.
Boess FG; Monsma FJ; Bourson A; Zwingelstein C; Sleight AJ
Ann N Y Acad Sci; 1998 Dec; 861():242-3. PubMed ID: 9928266
[No Abstract] [Full Text] [Related]
13. Differences in the central nervous system distribution and pharmacology of the mouse 5-hydroxytryptamine-6 receptor compared with rat and human receptors investigated by radioligand binding, site-directed mutagenesis, and molecular modeling.
Hirst WD; Abrahamsen B; Blaney FE; Calver AR; Aloj L; Price GW; Medhurst AD
Mol Pharmacol; 2003 Dec; 64(6):1295-308. PubMed ID: 14645659
[TBL] [Abstract][Full Text] [Related]
14. A single point mutation (Phe340-->Leu340) of a conserved phenylalanine abolishes 4-[125I]iodo-(2,5-dimethoxy)phenylisopropylamine and [3H]mesulergine but not [3H]ketanserin binding to 5-hydroxytryptamine2 receptors.
Choudhary MS; Craigo S; Roth BL
Mol Pharmacol; 1993 May; 43(5):755-61. PubMed ID: 8388989
[TBL] [Abstract][Full Text] [Related]
15. Conserved helix 7 tyrosine functions as an activation relay in the serotonin 5HT(2C) receptor.
Rosendorff A; Ebersole BJ; Sealfon SC
Brain Res Mol Brain Res; 2000 Dec; 84(1-2):90-6. PubMed ID: 11113535
[TBL] [Abstract][Full Text] [Related]
16. Identification of an amino acid residue important for binding of methiothepin and sumatriptan to the human 5-HT(1B) receptor.
Grånäs C; Larhammar D
Eur J Pharmacol; 1999 Sep; 380(2-3):171-81. PubMed ID: 10513577
[TBL] [Abstract][Full Text] [Related]
17. Heterologous desensitization is evoked by both agonist and antagonist stimulation of the human 5-HT(7) serotonin receptor.
Krobert KA; Andressen KW; Levy FO
Eur J Pharmacol; 2006 Feb; 532(1-2):1-10. PubMed ID: 16487959
[TBL] [Abstract][Full Text] [Related]
18. Site-directed mutagenesis of the human 5-HT1B receptor.
Grånäs C; Nordvall G; Larhammar D
Eur J Pharmacol; 1998 May; 349(2-3):367-75. PubMed ID: 9671119
[TBL] [Abstract][Full Text] [Related]
19. Activation of constitutive 5-hydroxytryptamine(1B) receptor by a series of mutations in the BBXXB motif: positioning of the third intracellular loop distal junction and its G(o)alpha protein interactions.
Pauwels PJ; Gouble A; Wurch T
Biochem J; 1999 Oct; 343 Pt 2(Pt 2):435-42. PubMed ID: 10510311
[TBL] [Abstract][Full Text] [Related]
20. [3H]5-hydroxytryptamine labels the agonist high affinity state of the cloned rat 5-HT4 receptor.
Adham N; Gerald C; Schechter L; Vaysse P; Weinshank R; Branchek T
Eur J Pharmacol; 1996 May; 304(1-3):231-5. PubMed ID: 8813606
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
