145 related articles for article (PubMed ID: 16614166)
1. Paclitaxel and docetaxel stimulation of doxorubicinol formation in the human heart: implications for cardiotoxicity of doxorubicin-taxane chemotherapies.
Salvatorelli E; Menna P; Cascegna S; Liberi G; Calafiore AM; Gianni L; Minotti G
J Pharmacol Exp Ther; 2006 Jul; 318(1):424-33. PubMed ID: 16614166
[TBL] [Abstract][Full Text] [Related]
2. Defective taxane stimulation of epirubicinol formation in the human heart: insight into the cardiac tolerability of epirubicin-taxane chemotherapies.
Salvatorelli E; Menna P; Gianni L; Minotti G
J Pharmacol Exp Ther; 2007 Feb; 320(2):790-800. PubMed ID: 17135345
[TBL] [Abstract][Full Text] [Related]
3. Paclitaxel and docetaxel enhance the metabolism of doxorubicin to toxic species in human myocardium.
Minotti G; Saponiero A; Licata S; Menna P; Calafiore AM; Teodori G; Gianni L
Clin Cancer Res; 2001 Jun; 7(6):1511-5. PubMed ID: 11410484
[TBL] [Abstract][Full Text] [Related]
4. Preclinical evaluation of the cardiotoxicity of taxane-anthracycline combinations using the model of isolated perfused rat heart.
Platel D; Pouna P; Bonoron-Adèle S; Robert J
Toxicol Appl Pharmacol; 2000 Mar; 163(2):135-40. PubMed ID: 10698671
[TBL] [Abstract][Full Text] [Related]
5. The novel anthracenedione, pixantrone, lacks redox activity and inhibits doxorubicinol formation in human myocardium: insight to explain the cardiac safety of pixantrone in doxorubicin-treated patients.
Salvatorelli E; Menna P; Paz OG; Chello M; Covino E; Singer JW; Minotti G
J Pharmacol Exp Ther; 2013 Feb; 344(2):467-78. PubMed ID: 23192654
[TBL] [Abstract][Full Text] [Related]
6. Pharmacokinetic profiles of doxorubicin in combination with taxanes.
Holmes FA; Rowinsky EK
Semin Oncol; 2001 Aug; 28(4 Suppl 12):8-14. PubMed ID: 11552225
[TBL] [Abstract][Full Text] [Related]
7. Time-related increases in cardiac concentrations of doxorubicinol could interact with doxorubicin to depress myocardial contractile function.
Mushlin PS; Cusack BJ; Boucek RJ; Andrejuk T; Li X; Olson RD
Br J Pharmacol; 1993 Nov; 110(3):975-82. PubMed ID: 8298821
[TBL] [Abstract][Full Text] [Related]
8. Anthracycline metabolism and toxicity in human myocardium: comparisons between doxorubicin, epirubicin, and a novel disaccharide analogue with a reduced level of formation and [4Fe-4S] reactivity of its secondary alcohol metabolite.
Minotti G; Licata S; Saponiero A; Menna P; Calafiore AM; Di Giammarco G; Liberi G; Animati F; Cipollone A; Manzini S; Maggi CA
Chem Res Toxicol; 2000 Dec; 13(12):1336-41. PubMed ID: 11123976
[TBL] [Abstract][Full Text] [Related]
9. Drug interactions with the taxanes: clinical implications.
Baker AF; Dorr RT
Cancer Treat Rev; 2001 Aug; 27(4):221-33. PubMed ID: 11545542
[TBL] [Abstract][Full Text] [Related]
10. Taxoids in combination with anthracyclines and other agents: pharmacokinetic considerations.
D'Incalci M; Schüller J; Colombo T; Zucchetti M; Riva A
Semin Oncol; 1998 Dec; 25(6 Suppl 13):16-20. PubMed ID: 9865687
[TBL] [Abstract][Full Text] [Related]
11. Study of dose escalation and sequence switching of administration of the combination of docetaxel and doxorubicin in advanced breast cancer.
Itoh K; Sasaki Y; Fujii H; Minami H; Ohtsu T; Wakita H; Igarashi T; Watanabe Y; Onozawa Y; Kashimura M; Ohashi Y
Clin Cancer Res; 2000 Oct; 6(10):4082-90. PubMed ID: 11051260
[TBL] [Abstract][Full Text] [Related]
12. Secondary alcohol metabolites mediate iron delocalization in cytosolic fractions of myocardial biopsies exposed to anticancer anthracyclines. Novel linkage between anthracycline metabolism and iron-induced cardiotoxicity.
Minotti G; Cavaliere AF; Mordente A; Rossi M; Schiavello R; Zamparelli R; Possati G
J Clin Invest; 1995 Apr; 95(4):1595-605. PubMed ID: 7706466
[TBL] [Abstract][Full Text] [Related]
13. Compilation of phase I and II trial data of docetaxel and doxorubicin in the treatment of advanced breast cancer and other malignancies.
Sparano JA
Semin Oncol; 1998 Dec; 25(6 Suppl 13):10-5. PubMed ID: 9865686
[TBL] [Abstract][Full Text] [Related]
14. Doxorubicin/taxane combinations: cardiac toxicity and pharmacokinetics.
Sparano JA
Semin Oncol; 1999 Jun; 26(3 Suppl 9):14-9. PubMed ID: 10426454
[TBL] [Abstract][Full Text] [Related]
15. Anthracycline cardiotoxicity in breast cancer patients: synergism with trastuzumab and taxanes.
Gianni L; Salvatorelli E; Minotti G
Cardiovasc Toxicol; 2007; 7(2):67-71. PubMed ID: 17652806
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of Anthracycline Alcohol Metabolite Formation in Human Heart Cytosol: A Potential Role for Several Promising Drugs.
Mordente A; Silvestrini A; Martorana GE; Tavian D; Meucci E
Drug Metab Dispos; 2015 Nov; 43(11):1691-701. PubMed ID: 26265744
[TBL] [Abstract][Full Text] [Related]
17. Pharmacokinetic interactions of paclitaxel, docetaxel and their vehicles with doxorubicin.
Colombo T; Parisi I; Zucchetti M; Sessa C; Goldhirsch A; D'Incalci M
Ann Oncol; 1999 Apr; 10(4):391-5. PubMed ID: 10370780
[TBL] [Abstract][Full Text] [Related]
18. Phase I trial of cremophor EL with bolus doxorubicin.
Millward MJ; Webster LK; Rischin D; Stokes KH; Toner GC; Bishop JF; Olver IN; Linahan BM; Linsenmeyer ME; Woodcock DM
Clin Cancer Res; 1998 Oct; 4(10):2321-9. PubMed ID: 9796961
[TBL] [Abstract][Full Text] [Related]
19. Doxorubicin irreversibly inactivates iron regulatory proteins 1 and 2 in cardiomyocytes: evidence for distinct metabolic pathways and implications for iron-mediated cardiotoxicity of antitumor therapy.
Minotti G; Ronchi R; Salvatorelli E; Menna P; Cairo G
Cancer Res; 2001 Dec; 61(23):8422-8. PubMed ID: 11731422
[TBL] [Abstract][Full Text] [Related]
20. Doxorubicin and taxane combination regimens for metastatic breast cancer: focus on cardiac effects.
Valero V; Perez E; Dieras V
Semin Oncol; 2001 Aug; 28(4 Suppl 12):15-23. PubMed ID: 11552226
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]